About Vasant Narasimhan
Vasant Narasimhan, CEO of Novartis, discussed the company's second-quarter 2024 performance in a July 21 interview, noting that the first half of the year involved navigating "the largest expertise in our history" while the second half is focused on investing in the pipeline and launches to sustain 5 to 6% growth. He stated that despite a "big beat" in the quarter, the company chose not to raise full-year guidance to maintain investment levels, with a reevaluation planned for the third quarter. Narasimhan also addressed patent expirations for drugs like Entresto and Cosentyx, expressing confidence that Novartis can grow through 2031 with assets such as Pluvicto and Kisqali.
Narasimhan commented on the company's acquisition strategy, stating that larger deals are evaluated when they bring new capabilities and late-stage assets in core therapeutic areas, citing acquisitions like Avidity, The Medicines Company, and two radio ligand therapy companies. He described radio ligand therapy as a potential $25 to $30 billion segment and noted that Novartis has built manufacturing capacity, including eight facilities in the US and a network in Europe and Asia, to support over 900 sites in the US and 800 internationally. He also expressed concern about the European market, stating that only 60% of new medicines are launched in a timely manner there and predicting that percentage could decline further.
Source: AI-verified profile updated from Vasant Narasimhan's recent appearances.
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Transcript (83 segments)
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Steve Sedgwick0:00
Every leader's journey is shaped by a handful of defining decisions. Those moments of risk, doubt, and conviction that influence their lives and careers. In this podcast, we get to hear the stories behind those choices. Welcome to Executive Decisions with me, Steve Sedgwick.
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Vasant Narasimhan0:23
I think it's easy to get too fixed kind of in your career as well. And yet I think to be open to possibilities that a decision in one direction could open three other decision doors in another direction.
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Steve Sedgwick0:33
As the son of two first generation immigrants to United States, Vas's life and career have been guided by a core mission instilled by his parents.
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Vasant Narasimhan0:42
By bringing me back to India. Many times in my youth, particularly my mom, she would always take us back to say you've had these extraordinary opportunities to get to the US to get an education. What could you do for the world? Like what could you do to impact the world with the opportunities that you've been given?
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Steve Sedgwick0:58
After attending Harvard Medical School, Vas considered becoming a doctor, but instead he went to consultancy McKinsey before settling at Novartis. When he eventually became CEO, the company was embroiled in scandal and faced several investigations.
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Vasant Narasimhan1:12
Talk about getting thrown into the maelstrom. It's easy to coach new CEOs about these things, but when you go through it and it's the first time it's your name and seeing all of that, it's jarring.
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Steve Sedgwick1:22
These are Vas Narasimhan's Executive Decisions.
I've had the privilege of interviewing you throughout your career as a CEO at Novartis, but I haven't got to know you. And as my preparation for this has gone on, I've just found you unbelievably fascinating already as well. Why don't we start off earlier on though with your parents and the importance of where you come from?
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Vasant Narasimhan1:51
Hey, look, Steve, I always say we stand on the shoulders of giants. And I think about the journey of my grandparents coming from really small villages in southern India, farming villages. My parents making the grand trek from India to the United States, and then growing up as an immigrant kid in Pittsburgh, Pennsylvania, a steel town, but it was a steel town back then. And they put inside of me the values that I think I cared for today. You try to impact the world in a positive way. You do it with humility and kindness. You're always trying to learn about yourself and learn about the world. So, it's been, I'm very grateful for all that they've done.
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Steve Sedgwick2:30
Your mother was a nuclear engineer. Your father was a senior executive at Hoeganaes Corporation as well.
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Vasant Narasimhan2:35
Good research. Yeah.
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Steve Sedgwick2:36
Well, thank you. We try. Having a mom especially with that kind of pedigree is phenomenal.
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Vasant Narasimhan2:41
My mom is a brilliant, brilliant person and she managed to raise three boys while being a nuclear engineer at Westinghouse while still trying to make ends meet. So I think that was really important for us to see, right growing up. And then my father having come from nowhere to come all the way up to the executive ranks. Even during his career he would make multiple steps where really high-risk steps, leave his job, get another degree, bet on himself again and again, always with this kind of boundless optimism, and I think that carried through into me as well.
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Steve Sedgwick3:14
Yeah. I read somewhere that you one of your key aims as a young man was just trying to fit in. You know you're coming from an immigrant background as well. Was it hard to fit in?
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Vasant Narasimhan3:24
Well, you know, I think it was, but we had a beautiful community there in Pittsburgh. Actually, my parents helped found a temple there. And I actually grew up, even though I was growing up in the United States, I grew up really grounded in Indian culture, Hinduism. Books I now still quote like the Bhagavad Gita were important in my upbringing. So, I always had a sense of belonging there. But of course, at that time, there wasn't large immigrant communities in these places where I was going to school. So a big focus was yeah just trying to fit in. You know sometimes it was funny, I would only know the words for things and the language I learned first which was Tamil not English, and always trying to catch myself when the kids would then laugh at me. I mean little things like that, but it was still a wonderful childhood.
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Steve Sedgwick4:09
What drove you as a young man?
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Vasant Narasimhan4:11
You know, I think my parents instilled in me this idea by bringing me back to India many times in my youth, particularly my mom. She would always take us back to say you've had these extraordinary opportunities to get to the US to get an education. What could you do for the world? Like what could you do to impact the world with the opportunities that you've been given? And going back and seeing that of course especially at that time in India you would be seeing that there are millions, hundreds of millions of people without those opportunities, and so I was left with that thought that I've had the privilege to have these opportunities, it's not a given, just a luck of the draw in many ways, and then what can you do with that to make the world better.
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Steve Sedgwick4:50
Yeah. Did you always want to be a doctor?
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Vasant Narasimhan4:52
I think very early on, if you probably saw in the history even in college, I went to Africa and I went to West Africa and I went to the Gambia, to work with the Red Cross, and probably it was that experience that more than any other really instilled in me this desire to pursue medicine and public health.
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Steve Sedgwick5:09
Because you also looked at child poverty in India and you were in Kolkata and other places, studying HIV treatments in Botswana. Part of me can see how you could have gone down that route and stayed with people at Medicine San Frontier and working in humanitarian relief, working in the charity sector as well. I can easily have seen you going that way given your resume.
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Vasant Narasimhan5:27
Well, first I want to make a call out there. You know, when you go back to Kolkata, that was actually the first trip my wife and I took and we had only been dating for like 3 months and we ended up working with street children and child laborers in Kolkata together. So, think about a love story. That was like an interesting place to kind of, but we it was a crazy, crazy time then in Kolkata but we managed and it was incredibly rewarding. And then as you said, to be part of the first HIV AIDS treatment effort in Africa and Botswana was extraordinary. But you know through those experiences I also saw that in many of these ways, management, leadership was not very evolved in public health and so I think my first step into the business world was very much motivated by that desire to learn how to lead, learn how to make change happen at scale because I think the history is that usually a great physician is just thrust into a leadership role without any of the experience, and that's what I was observing on the ground. So that's where the initial inclination came from. Now I had no idea I would end up being a CEO. It was always like I'm going to go to business and come back to public health and then one thing led to another.
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Steve Sedgwick6:35
It's really interesting because more than one of my guests on this podcast said I always knew I was going to be a CEO. I always knew that was the aspiration as well, but for you that wasn't the goal. That wasn't you weren't making an early decision to be a CEO. I think the idea of becoming a CEO only fully occurred to me 6 months before I became CEO of Novartis.
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Vasant Narasimhan6:47
Genuinely?
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Steve Sedgwick6:52
Genuinely
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Vasant Narasimhan6:53
But you had you had a whole series of management roles, we'll come to your evolution of your career from 2005 onwards over at Novartis. But I would have thought that it would have been at the back of your mind.
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Steve Sedgwick7:03
You know, when the global head of human resources then at Novartis said I was one of the candidates that they were considering for the CEO role, I thought he was actually joking. I mean, I was like, me? I'm like a physician scientist working on drug development. Yeah. So, it never occurred to me honestly.
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Vasant Narasimhan7:18
Sorry Vas, You're one of the smartest people I know, how did you not spot that?
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Steve Sedgwick7:21
I missed it. But, you know, I'm kind of, another thing my parents gave me was this notion you have to throw yourself fully into whatever you're doing at that moment because who knows what comes next. And don't worry about the result. Throw yourself into the process. Whatever role I was in, I was all in and it never was thinking about and that's the best advice I'd give to young people listening. Don't always think about the next role. I mean, think about how you can maximize the experience of the role you're in.
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Vasant Narasimhan7:47
You are a very smart guy. Although you're the second smartest person in your marriage from what I can see. Your wife's got more Harvard degrees than you.
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Steve Sedgwick7:53
That's absolutely true. Absolutely true.
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Vasant Narasimhan7:55
But you kind of found it easy to talk to smart people on a smart level but actually hence you mentioned the scientists but on a broader level not everyone's got your IQ Vas, you know, and did you find it hard to relate to the rest of us the mere mortals of us out there.
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Steve Sedgwick8:08
Well, I think there is that element of communication, but I think there's also an element of getting to what are the underlying things that drive people and really understanding that it's okay that people have different motives and different drives, but you as a leader have to find a way to tap into that and really get people to do extraordinary things. That's what we tell leaders. Leadership at Novartis is getting ordinary people to do extraordinary things. That's what we need to be able to do. Autonomy, mastery, purpose. It kind of covers it, doesn't it?
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Vasant Narasimhan8:34
Autonomy, mastery and purpose. Yeah. So Daniel Pink's work and we've I've talked to Daniel now still ongoing for many years. I still believe he's got it. For most people once you pay them enough, it's not paying them more is not going to motivate them even more. But it's the idea that they're working for something that's bigger than them. That they have the freedom to do that work which we later called unboss and then the opportunity to grow as people. You should really be talking about mission and purpose three times more than anything else. I mean many people have talked about this. Simon Sinek, Adam Grant, many of the leaders that I really think again Adam Grant. Yeah, you know, start with why. Leaders start with why. And you should be talking about the why we're doing the work three times as much as the what and the how because that's what really can motivate people. But the art of it is not just the big P purpose always. I've learned over the years it's not the big P purpose always. You also got to bring it down to the little P purpose. I love the story of people who work in our manufacturing facilities cleaning the facilities. And when you ask them why do they do what they do at Novartis, they say we're saving people's lives. Yeah. Because they've connected the work they do in that facility to the bigger purpose. And so you have to be able to make those connections. It's not enough just to say let's reimagine medicine because somebody in our organization seven eight levels down has to understand what that means for them.
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Steve Sedgwick9:52
I want to just mention your wife as well because we've already talked about her. She's an incredible woman in her own right. She's the CEO of Idorsia pharma now as well, lives with you in Basel with your kids. She's got four Harvard degrees, which I hasten to add is more than you, isn't it? I think so. It is. But you've mentioned her about three times, so she deserves an honorable mention as one of your key... She's your partner in this, isn't it? This isn't just you, the CEO. This is you together, isn't it?
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Vasant Narasimhan10:17
Absolutely. And my best friend as well, but I think throughout the ups and downs, we've been on this project, whether it's the streets of Kolkata, whether it's the hospitals of Africa. Now, interestingly, both as biopharmaceutical CEOs. I haven't, I'm not sure if it's true, but I think we might be one of the few or the only married couple that's both CEOs of public companies, maybe in the world, which is kind of incredible thing. Um, yeah. So, it's been extraordinary and I would be nowhere without her. Uh, for sure.
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Steve Sedgwick10:48
One thing that's really clear is having one amazing career is tough on the family and is tough on the relationship. Having two amazing careers, you must make some really tough decisions. And again, this is not a Novartis thing. This is about you and your amazing partner in life. How do you make those decisions about what you prioritize and when you prioritize?
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Vasant Narasimhan11:07
Yeah, I think early on when the boys were young, we have two incredible incredible boys. Early on, actually I took the lead. She was traveling. She was a McKinsey expert. She was traveling around the world working on projects. I was kind of muddling my way through as best I could trying to get the kids to daycare. Then, you know, she took the lead on the kids and my career at Novartis really blossomed. And then, look, when the opportunity to become a CEO came up, we talked with the boys and we said, 'Are we willing to do this as a family?' And my boys said, 'We want to make this happen for our mom.' And so, we figure it out. I mean, and so it's not always easy. I don't have a magic formula to make it happen, but we figure it out.
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Steve Sedgwick11:45
Quickly, you just mentioned McKinsey. Why did you join McKinsey? After all the amazing life experiences you had after from Botswana to Gambia to Kolkata, you end up at McKinsey.
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Vasant Narasimhan11:54
Yeah, it was interesting. But you know, I am very grateful. I was there. I was there for 18 months, 20 months. But in that time, I learned so much for somebody who'd never been, you know, done an MBA or knew anything. I didn't know what a balance sheet was. I didn't know anything about P&Ls and valuation. And I'd been trained in medicine. And then I learned all of that and I got to apply it in the business world. I think of it as I learned another language. Like you have to as leaders you have to be able to speak different languages, you have to speak medicine, public health, finance and business, and you have to be able to communicate and I learned that.
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Steve Sedgwick12:28
But that decision speaks volumes to me. You didn't go to one of the big hospitals, you didn't go to big teaching hospital to carry on that side of your career. You went to McKinsey instead because you knew you wanted to make a bigger impact in health and health services. It wasn't going to be medicine, it was going to be scientific?
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Vasant Narasimhan12:42
I wasn't exactly sure, you know. And that's the point, young people shouldn't be sure. I mean, I think people watching should know these were all just experiments. I was in my kind of late 20s. I was like, go, let's give it a shot, right? Maybe McKinsey will lead to something or maybe I'll just go back to medicine. And I had no idea where it would go and I had no idea that McKinsey would lead to Novartis, right? So then when that happened and then suddenly I was sitting in Basel, Switzerland working for a pharmaceutical company. Suddenly my mother was asking me what exactly is the plan right now? So I thought you were going to, you know, be working at a hospital. You're a Harvard Medical School grad. I'm with your Mom, this is where I was going with your history.
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Steve Sedgwick13:17
Exactly. And it wasn't a carefully thought through plan at all. It was kind of just trying to see where I could learn, where I could have an impact and just kind of..
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Vasant Narasimhan13:25
So, I love this - huge decision. You've had this unbelievably expensive education. I'm sure you got a loan the size of a ... Well, maybe you didn't. So, you've made the decision to go to McKinsey to learn more and then you've ended up at Novartis 2005?
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Steve Sedgwick13:39
2005.
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Vasant Narasimhan13:39
Tell me how that process worked and the decision making, did you make that more of a decision or were you just winging it still?
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Steve Sedgwick13:44
I kind of always thought to follow people I respected and there were some great leaders there that I respected. Got a gentleman named Amit Malik who's actually now still a biopharmaceutical CEO. He told me look you should come and I think you can learn a lot and have a huge impact. And so I trusted him, right? And I think a lot of these, look in life you also trust the people who believe in you and that can open up a lot of doors and that actually ended up being quite a decision to take, though at the time again seemed like a very strange decision to take.
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Vasant Narasimhan14:15
Um a whole series of roles between 2005 and late 2017 early 2018 when you became the CEO. Tell me about some of the great decisions you made in that period and tell me some about some of the howlers where I presume you learned also a lot.
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Steve Sedgwick14:30
I mean so the big one was 2006 after two years at Novartis Pharmaceuticals in the main ship Basel Switzerland. I went to the newly acquired vaccines division which was losing money, had a very small piece of Novartis, 2% of Novartis' sales, and at the time seemed like a very strange decision again. And so I had a series of strange decisions. Always following trying to follow mission, learning, purpose. That ended up being one of the great decisions because what happened is when you go to a small unit and you get huge responsibility your learning curve goes up through the roof. So I was suddenly overseeing clinical programs and development programs and in our world important things to know, all the way through to marketing launch programs. I had to solve all kinds of issues and it was fully immersive. You know, I ended up being seven years, I was there eight years I was in that division. And it was actually incredible. Before I knew it, I was running a unit and I was testifying in front of Congress about the H1N1 pandemic. And I wasn't even 32 years old at that point in time. So, I think that was one of those decisions where at the time to most people seemed like a really bad decision that in retrospect, I mean, for my growth, it was incredible. Really really incredible.
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Vasant Narasimhan15:44
And that's incredible for me. I've just learned something again from this in the fact that I've had so many conversations with you about the rest of the industry about biotech. Why do you need them when you've got the big pharma and you just answered the question? It's the autonomy and the speed of action and what you can do and what you can learn and the responsibility that you as an individual in a smaller group get.
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Steve Sedgwick16:04
Absolutely. And you can make some big wins because you can take the risks because the downside is not as, look Novartis has to manage a huge risk profile. I mean, we're a 270 billion market cap company. When you're a small unit just trying to experiment, you just have to figure it out. Sometimes you'll win, sometimes you won't. And that's okay. So, I think that was a really interesting decision. The other one I'll tell is and I don't know again it's always hard, you know, in Buddhism to say who is to say what is good or not good because often things that seem good at the time end up being bad. Sometimes the thing bad at the time end up being good, but it's all just the cycle of how these things work. I remember in 2014, Novartis actually sold the vaccines division to Glaxo Smith Kline. And at the time, you know, I wasn't exactly sure if you can imagine that less than four years from there, I would become CEO of the company. I did not have a next role at Novartis. And I wasn't exactly sure would I go with the acquisition to GSK or would I find a role? And then I got a call from our CEO at the time and said, 'We're going to send you to the generics division, Sandos, in Germany.' and immersed myself in it and then 5 months later I got another call and I was the head of drug development at Novartis Pharmaceuticals and 3 years later I'm the CEO of the company. So these are really hard to predict how these things unfold.
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Vasant Narasimhan17:21
Yeah, I would imagine as part of you may have thought I really like this autonomy. I like the scale of the company. I'm going to stay with either this vaccine company with Glaxo or actually go elsewhere and become a vaccines CEO or a biotech CEO. I think it's easy to get too fixed kind of in your career as well. And I think to be open to possibilities that a decision in one direction could open three other decision doors in another direction.
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Steve Sedgwick17:45
Tell me about something you got really badly wrong early in your career. Everyone I know has and everyone I've interviewed pretty much I thought this was going to be the moment where I'm booted out the door kind of thing. Did you have a one or two moments where obviously you learned from it but you had a really hard time at the time?
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Vasant Narasimhan18:00
Well, I think certainly when I coming back, I mean there are many of these moments as you can imagine, but you know I think one that comes to mind in that early part of the career is you know as a very ambitious leader of Novartis vaccines North America, I convinced the US government to actually have us become the number one supplier during the swine flu pandemic and we were the number one supplier we won the contracts and then that summer we weren't able to deliver initially. And I still remember the meetings with the then CEOs and chairman and that I put the whole company's reputation at risk by ambitiously signing up for these deals and then not being able to deliver and then being called in front of Congress as well to testify about it and being called by the chief of staff of the White House and oh that was a tough summer. But here's the interesting thing. I mean, what I also learned in that experience is to go to manufacturing sites and really try to talk to people in town halls and say, 'We can do this. I know we're behind. We can get there. We can get there.' And we did get there. We did deliver it.
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Steve Sedgwick19:05
So, you motivated people as well. You learned how to motivate people when with a gun to your head, of course. And we figured it out.
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Vasant Narasimhan19:10
How was it mentally for you at the time? These failures these setbacks. At the time I had one CEO saying one of the similar I was in a fetal position. I was so upset. I had another one saying I was making really bad decisions. I had high levels of cortisol. My mind was I couldn't sleep. I hear a lot. What about you?
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Steve Sedgwick19:33
I think earlier I mean now I'm more zen about these things having gone through the ringer many times. But then tough to sleep. It's completely normal. I can tell you as a physician I mean these are the fight and flight responses. Used to be we were chased by animals when we were evolving as an ape species. Now it's the email you get saying, 'What the hell did you just do?' Right. And welcome to my life at CNBC. More like what did you just say? And yeah, and then of course you have the cortisol going, you don't sleep, you're under huge stress. And of course the hardest part is how do you insulate your organization from that? So I found over the years it was so important that you absorb it and then that's very heavy load on you. But if you let it pass through you into the organization, then the organization simply cannot perform. You have to be absorptive buffer. Yeah. And that's hard and that's really hard on all leaders. So I think that's something we all have to contend with.
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Vasant Narasimhan20:25
Let's spin forward to the succession process from Joe Jimenez. 2017. Tell me how it worked. And about the decision you made to accept that role because you've already said on this podcast as well, you never expected to be the CEO.
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Steve Sedgwick20:41
I think that was the moment when I actually just sat down and I said I'm going to write down what I believe this company should become on a single sheet of paper and I think if I still keep that sheet of paper and it was very much around the cultural transformation - inspired, curious and unbossed - not quite those words yet but that Dan Pink concepts I wanted to bring in. That I truly believe that we should be a pure play innovative medicine company and that we should bet on technology innovation. I called it data and digital I didn't know about AI, so I wrote go big on data and digital. That became kind of the manifesto. Now, it took much longer than I ever expected to do all of those things, but that was it. And then I went through the process and I remember still it was a board meeting. I got called in by the chairman. He told me I'm going to become the next CEO and I was over really incredibly excited. I ran upstairs to call my wife Shristi and she said, 'Look, I'm in a meeting. Could I call you back later?' And she just quickly hung up. So I was like, 'Okay, I'm not allowed to tell anybody.' And then the funniest thing, I was actually had to go to fly to another meeting and I was actually on a Ryan Air flight. We were in Dublin where this board meeting is. And then I was like delayed in the Ryan Air and Dublin airport for like 12 hours. I was like, 'Here it is. I've been named CEO of this giant company.' And the reason I keep coming back to that is it's how do you stay humble and grounded throughout the whole thing, right? And I think it's so important.
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Vasant Narasimhan22:07
Well I think you stay humble and grounded by traveling on Ryan Air. All due respect to the great Michael O'Leary. That's as humbling as it gets.
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Steve Sedgwick22:15
Yeah. A good reminder. That's hero to zero stuff as well.
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Vasant Narasimhan22:24
The first year as CEO was rough. You walked straight into a crisis. For our viewers and listeners, 3 months into the post, you had to apologize to employees and indeed you were hauled over the coals publicly with a lot of truths and a lot of untruths as well about the fact that your company had hired Michael Cohen's consulting company in February 2017, which is way before you became CEO, a 1.2 million year-long contract as well. That was perhaps in retrospect, I think very clearly, not the right thing for Novartis to do, but you had to bear the brunt straight away.
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Steve Sedgwick22:58
Yeah, I think that first six months, we had the Michael Cohen situation. We also had a very large Greece investigation from the SEC DOJ. We had another investigation and to practices in Asia and talk about getting thrown into the maelstrom. And I think it's easy to coach new CEOs about these things, but when you go through it and it's the first time it's your name and seeing all of that it's jarring right.
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Vasant Narasimhan23:23
I remember talking to you about it and I'll put my hands up here you stood up you took the questions you know this wasn't your mess, but you'd inherited it as a senior member of the team that had hired Michael Cohen and now the CEO as well. Yeah, unbelievably tough.
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Steve Sedgwick23:38
Very very tough. I also say I mean I made some missteps throughout that whole process.
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Vasant Narasimhan23:42
What mistakes did you make?
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Steve Sedgwick23:43
Look, I think I should have owned it on behalf of the company. My first response is I think I even said on maybe it was on CNBC, look, this didn't happen under my watch. That doesn't matter right now. I'm the steward of the company. I need to own it. And I think in retrospect, I should have just said doesn't matter. Our company shouldn't have done this, you know, and we need to own it. And then step forward. So I think I learned a lot in that whole process that first six months because then it came straight to Greece, the Alcon investigation in Asia and then 2019 the FDA investigation to manipulated data on a gene therapy as well. I mean you are firefighting from day one for a good 18 months.
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Vasant Narasimhan24:23
Yeah it was 18 months of trial by fire. It builds a thick skin that's for sure. You need that in this job. But it's hard to build a thick skin without taking some of that.
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Steve Sedgwick24:33
Did you question then at any moment your decision to become CEO?
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Vasant Narasimhan24:39
No, I think I was at that point kind of the, you know, another thing my parents instilled in me is you stay in the ring. I mean because in the end just staying in the ring is hard enough, right? And if you can stay in the ring, stay resilient that you can overcome if you just keep getting back up.
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Steve Sedgwick24:54
You're getting a lot of brick bats thrown at you from people who have never been in the ring. Absolutely. And if they haven't been in the ring, and I feel like this on CNBC, I don't care what they say. If they've never been in the position, they don't understand what it's like.
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Vasant Narasimhan25:05
They don't understand what it's like. But, you know, I think in I have a much more mature perspective then, but I mean, back then, I was very angry at the journalist community. I was like, why are they bashing me and it was tough.
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Steve Sedgwick25:16
You didn't show it to me, which I'll take on board. Look, another really, really tough decision amidst the pandemic, eliminating 10,000 jobs. That is without doubt the toughest decision of your career, isn't it?
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Vasant Narasimhan25:28
For sure. I mean, and these were all things I kind of always knew that we needed to do and that I struggled with, I think, for because it was the pandemic, there was always a reason not to do it. A company I had grown up at, company where I knew so many people around the world and then to take out over 10% of our workforce, many people I knew was really, I think, a tough decision. Funny enough, again, I spoke to the CEO about a very similar decision that he had to make when he became CEO. Same kind of numbers, huge 10,000 plus people as well. He said, 'As long as you do it with respect and you're respectful to the employees you're letting go of and the employees who are still there and you explain to them exactly why you're doing this, then it's a much easier process.' I think to a person that I would interact with, they all understood because we really took the time to explain why, like why strategically this makes sense, why we need to focus as a pure play, why we need to simplify, why we need to streamline down the pipeline and spending that extra time saying why. I think people understood. No, this still the personal impact of individuals leaving and you know Basel is a small place so everybody knows everybody, so a lot of people, my kids friends parents, so it was a tough time. It turned out as you've seen the performance it was the right move, but that's not a given and I think it was a tough couple years.
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Steve Sedgwick26:51
I would imagine in your position there is nothing more exciting, nothing that validates the decisions you've made when you get drugs through that change people's lives. I want to know about that feeling when you've backed a drug. It works. It's got past stage three and you know this is going to make a big difference.
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Vasant Narasimhan27:10
I cry every time we have a phase three win. It doesn't surprise me because I mean many of these projects I've been with since 2013, 2014, or I started them or I know the teams and most of them sadly don't work right. And when you have one that really changes, in the case of Kisqali, the whole shape of breast cancer therapy, or Pluvicto prostate cancer, you know again cancer chronic myelogenous leukemia. I mean it's an extraordinary moment and it's not just those. I mean one of my favorite ones happened last November we discovered and successfully developed the first new malaria drug, coming back to my time in Africa, in 25 years. And so for me flashing back to sitting in a hospital in Tanzania and watching children die of malaria, knowing my company has provided Coartem to 1.2 billion people and then making that next discovery. Of course you cry because you put your whole heart and soul into this work. That's the only way you can do it.
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Steve Sedgwick28:03
We've covered a lot of ground about your personal ethos in making decisions. Just tell me how you want to put into words your ethos and your values when you make decisions.
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Vasant Narasimhan28:11
There's so many things we can be doing with our energy and our time. But one thing I've learned through this transformation process is we have to stay focused on what we're great at. Discovering developing the most cutting edge medicines. Just to give you an example, people always say why don't you get into devices, why don't you get into diagnostics, why don't you buy an AI company, and you know I think we have to stay on mission. That's the first first step. Second is it consistent with our responsibility to the stakeholders that we have. So people often ask me why do you still do malaria and leprosy and neglected tropical diseases, well that's aligned with our mission and we've made a commitment to global health for 100 years as a company. We've been the leader in global health and engaging in medicine in Africa. So we have to keep our commitments to those stakeholders. And then of course can you execute? I mean, in the end, there are sometimes things that are both of the first two things, but we're not the right company to do it. And those are tough decisions, right? You can find, I give you an example, a rare cancer medicine that aligned with our mission, consistent with our goal to deliver medicines to cancer patients, but too small to move the needle for a 60 billion revenue company. And then we have to say no. And that's hard to tell those scientists. Look, there's a biotech who's better served to do this. But those are also the tough choices we have to make.
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Steve Sedgwick29:28
I want to talk about you personally and the decisions you make in your life. I look at myself and I'm actually going to compare myself to you now. I'm like a poor man's Vas Narasimhan. I monitor my blood sugar. I try and sort my sleep out. I concern about my mental health, my physical health. I work on all of these and I work on my sleep. I got a sneaky feeling you work on all of those a little bit better than I do because I know that they're actually part of how you try and conduct your personal life as well.
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Vasant Narasimhan29:53
Well, so first I don't believe that's true. Steve, you're looking great. Can we just cut that bit? But look, I would say, you know, I am I do believe and it's been consistent. And I had a great friend and coach Scott Pelton who's helped me with this now for 15 years. Mindset, movement, nutrition, and recovery. Mindset. Can you put yourself in the right mindset every day to have high impact? Think about your high impact moments. Realize you're not your thoughts and emotions. And you have to be able to observe your thoughts and emotions to be able to navigate the craziness of what we have to deal with. Movement. I think any form of movement, but being more consistent, whatever it is, and I'm a big exerciser, but being consistent has huge huge benefit. Nutrition. I always say why do you eat? So sometimes I eat for performance, sometimes I eat for pleasure, but I don't just eat to eat. And that's very easy in today's world where you're surrounded by food everywhere. So, purposeful eating. And then of course recovery. And now my biggest obsession now is sleep with all kinds of approaches to try to figure out how to sleep better because I think sleep is the ultimate medicine in the end. But I think the biggest thing on all four of those is whatever you choose to do, just pick things and do them consistently. The hardest thing is to do these things consistently because the benefits just accrue and compound. And people ask me like how do you put up with the travel and it's because I do those things every single day in some form and then over years the benefits compound.
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Steve Sedgwick31:18
I'll bear that in mind. It's my consistency and I will go for that run again tomorrow. Final question. What are the big decisions for you personally going forward?
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Vasant Narasimhan31:28
First and foremost is helping my sons navigate their transition into college and really with my wife taking on her leadership role, I have had to learn how to become more of a lead parent. So, that's really on my mind. I mean, I want to make sure they have the next step sorted out. And then of course at some point like what's next for me and I think one of the hardest things as a CEO is you can only go into this 200% 300%. I have no idea when the moment will come but when the moment comes it's like yeah now what? I mean, I've had the greatest job I could have ever imagined in my life. Had unbelievable impact on the world, on Africa, on the planet, on medicine. So, that's kind of a daunting challenge, I have to say. And I don't have any insight. Maybe I'll come back to you, Steve, for some advice since you seem to know me really well. You can counsel me on whatever.
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Steve Sedgwick32:12
I don't know if I know you really well, but I've learned a lot about you for this podcast, and I've loved the journey as well. So, thank you so much indeed for your time, Vas Narasimhan. Appreciate it.
That was a great conversation with Vas Narasimhan, both personally and professionally. He's just so interesting. He's always wanted to make an impact. He's got such great role models from his education, but especially from his family. His hardworking immigrant parents really instilled the desire to make an impact, but strong ethics within him as well. 20-year plus career at Novartis. He's always wanted to progress humanity, to get these drug breakthroughs, which he said himself, they make him cry when he has them because he knows they're going to make a positive impact in people's lives. Personally, I want to be Vas Narasimhan. He concentrates on his sleep, his health, his mental health, his physical well-being, his nutrition. He's kind of a role model for a lot of us as well. A really fascinating guy. Thank you very much indeed for joining me on Executive Decisions. I would love to hear your feedback. Drop your thoughts in the comments or a review and please hit that follow or subscribe button.