We will accomplish the greatest mission, making the world a better place. This is an exciting day. It's my honor to guide you this morning and to welcome you to the Genesis Summit, the first Genesis Mission Summit. Let's not wait any longer. Let's get started.
America has always reached for the future first. And now, the Genesis Mission is set to go faster and farther than anything that came before.
We're in the midst of a computing revolution that is going to transform the practice of science and engineering in America.
We're on the path to doubling America's scientific productivity and impact within the decade.
This past year has been one of the most dramatic accelerations of quantum information technology in the history of American government.
In a short time, Genesis has secured major investments from federal agencies, industry, and international partners, and launched the Genesis Mission Consortium, bringing together public and private partners to collaborate on discoveries.
We've identified some of our nation's greatest scientific and technology challenges across energy, discovery science, and national security. The world's brightest minds across the national laboratories, industry, academia, and philanthropies are working together to solve these challenges.
The Genesis Mission to me is an opportunity of a lifetime.
Our growing community of partners has access to the Genesis mission platform to leverage AI, high-performance computing, quantum systems, and extraordinary scientific data sets, and the capabilities of all 17 national laboratories, including new next-generation supercomputers. The future isn't waiting. It's already happening.
We have plenty of evidence that this AI technology is working. We're seeing it in advanced manufacturing, in the simulation of the electric grid, and we are seeing it in microscopy.
Every new partner strengthens the platform. Every breakthrough expands what's possible. The Genesis mission is unlocking the next era of American scientific leadership.
Now, to get us started today, please join me in welcoming Michael Kratsios, the director of the Office of Science and Technology Policy at the White House. Michael serves as President Trump's chief advisor for science and technology. I've known Michael for a number of years, and in this role in the Trump administration, he does what we would want for any leader from the White House to do. He provides extreme vision, and excels us, and pushes us to excel. And he also provides us the resources and the top cover to be behind to make sure we have what we need to succeed as agencies and the scientific community at large. So, please join me in welcoming Director Michael Kratsios.
Good morning, everyone, and welcome to the Genesis Mission Summit. It is truly and truly exciting to be here with all of you today and to know what this gathering represents for all of us. 250 years after our nation's first great venture innovation, 87 years after the Manhattan Project, and 65 years after the Apollo program, we are once again mobilizing a grand vision and national effort for the achievement of our highest ambitions. When President Kennedy declared that Americans would set foot on the moon, he told the world that such a lofty goal would serve to organize and measure the best of our energies and skills. Now, at the dawn of artificial intelligence, with the Genesis Mission, we are set not just one goal, but many. Now, we choose not to just have one high achievement, but many grand challenges. America's greatest scientific achievements have been born of national mobilization paired with the construction of new institutions. The Genesis Mission is the next chapter in that tradition, and we work together to harness AI for scientific discovery at a scale no one else on the planet can match. That is what brings us here today, and that is the spirit that animates the Genesis Mission. So, thank you for being part of it.
Many thanks especially to you, Secretary Wright, and Under Secretary Hill, who'll be speaking shortly, for everything that you have done to make this great adventure possible. When President Trump launched the Genesis Mission in November of 2025 as America's premier AI for science initiative, he tasked us with building a discovery engine that would double the productivity of American science and engineering within a decade. We heard first during this goal from Secretary Wright and from Under Secretary Gill. It took us a second to figure out whether or not that was a good idea to talk about publicly. And I think it takes only someone like President Trump to make us think big and ultimately try to achieve something that's right out of the park. Now today, we are celebrating the culmination of DOE's ongoing efforts with initiatives from a number of other agencies, NSF, Department of Energy, HHS, NASA, USDA, NIST, DHS, DOT, and many, many more to come. Together, we are proud to announce that we're going to bring more than $5 billion in total commitments to fuel AI for Science takeoff across the entire government.
The challenges that we have set and will continue to set focus America's brightest minds on ambitious scientific and technological goals that will underwrite American prosperity and define technical progress for a century to come. The Genesis Mission sets out to produce a new operating model for American science, reinvigorating and modernizing the federal government's partnership with industry, academia, and philanthropy for both basic and use-inspired advances in science. In short, it's not just a whole-of-government program, but a whole-of-nation effort. And we see that in the room today here with us. Just yesterday, I had published a report to the President on reinvigorating the National Science and Technology enterprise titled Science: A New Golden Age. AI for Science and the Genesis Mission in particular is the culmination of the reforms suggested in that report.
As I wrote there, to realize the Genesis mission's potential requires us to address four key issues that would otherwise constrain AI native science. The first is problem selection. The second is institutional capacity. The third is data infrastructure, and the fourth is integration of AI capabilities in the digital realm with experimental infrastructure here in the material world. The grand challenges and national effort making up the Genesis mission today address all of these problems and put us on a path to achieving our most ambitious goals for AI assisted science.
The challenges fall into five broad themes, which cover the whole of American science and technology ecosystem and highlight the connection between fundamental and applied scientific work. I want to highlight the representative challenge from each of these buckets. And mind you, these are challenges that span across all the agencies I previously mentioned. To help Americans live longer, happier lives, I'm particularly excited for the continuation of AI for science efforts applied to curing pediatric cancer. This is a top priority for President Trump, which continues the initiatives he began in the first term with the National Pediatric Cancer Data Ecosystem. Department of Health and Human Services will be coordinating with NIH and the FDA to support researchers leveraging AI to integrate genomic, imaging, pathology, and clinical data into multimodal models and learn across distributed sources. This will enable robust models even for ultra-rare cancers and guide precision care and adaptive trial design.
To drive reliability and affordability of America's built environment, DOE and the Department of Transportation are partnering with AI developers, material manufacturers, academia, national laboratories, infrastructure owners, and other market participants to revolutionize construction longevity and efficiency. AI can run structural energy and materials data sets orders of multiple magnitudes faster than conventional methods, enabling breakthroughs in design, predictive maintenance, and cost-effective decommissioning. To rebuild American industrial strength, a number of challenges on AI enhanced manufacturing to usher in an era of digital assisted reindustrialization must occur. AI allows integration of real-time data from machines, products, processes, and supply chains. AI tools will help navigate dynamic industrial systems to find efficiency gains and uncover new manufacturing methods and products.
Now, to protect the nation from emerging threats, whether natural, accidental, or deliberate, the early detection and attribution of biological threats stands out as an especially pressing challenge. AI platforms can integrate metagenomic, clinical, or environmental signals to detect anomalous biological signatures, characterize novel behavior from sparse data, and give public health authorities the ability to rapidly and accurately discern the origin of biological incident and design and countermeasures. By employing AI to address these challenges, we're extending the frontiers of American discovery.
At the heart of the Genesis mission as a whole is the dream of producing autonomous physical laboratories that accelerate the pace of inquiry, a grand challenge in and of itself. Now, our old institutions and conventional experimental processes have become bottlenecks that slow the cycle hypothesis, experimentation, discovery, enabled by AI unless we build the tools fit for direct AI use. Here is where we are seeing thrilling self-reinforcing dynamic with AI for science. As the application of AI to conduct the conduct of science drives progress in AI and science. Now, this is a virtuous cycle will advance our understanding of the world around us for generations to come. I am so so grateful that all of you are partners. America's most creative minds in the industries have always answered the call when our country needed them most. The Genesis mission is that call to you to advance American scientific leadership in this grand era of artificial intelligence. We are setting for ourselves one grand challenge composed of many grand challenges, and I trust that we will soon see what new frontiers these efforts open for all of us. Thank you so much and good luck today.
