CEOInterviews.AI
Start App
Bill Ackman
CEO & Founder, Pershing Square

The Business of Design—and the Design of the Future

📅 Sep 21, 2026 Fast Company 35 MIN 1351 VIEWS 64 SEGMENTS · 3 SPEAKERS
Featuring Bill Ackman, CEO, Pershing Square Capital Management. Design is often treated as a finishing touch: Make it beautiful. Make it intuitive. Make it sell. But what if design is something much bigger—a way to imagine what doesn’t exist yet, connect ideas that don’t seem connected, and see possibilities before they become obvious? In this conversation, investor Bill Ackman explores how design has shaped the way he thinks about business, innovation, and the future—and what happens when you give bold ideas the time and freedom to evolve. As AI begins to transform the creative process itse...

What Bill Ackman said

Written from the verified transcript and checked against it. Every figure links to the moment it was said.

Bill Ackman discussed design, his daughter Lucy's brain hemorrhage recovery, and his new brain research institute. He corrected that his $400 million investment is already made, totaling about $700 million including real estate. He criticized the US healthcare system's incentives and reimbursement, advocating a for-profit solution. Ackman detailed the institute's 3.4-acre campus on 11th Avenue, bought for $191 million, with potential 2.5 million square feet of buildable area. He mentioned leading a funding round for Precision Neuroscience (raised $250 million, billion-plus post-money), and discussed AI's use of brain data. He criticized Mayor Mamdani's policies, praised the president's Iran war and 401(k) plan, and offered views on the bifurcated economy. He described mitochondrial injections for his daughter and the institute's patient-centric, Y Combinator-style approach.

Key takeaways

  1. Ackman committed over $700 million to a brain research institute in New York City, including $300 million in real estate.
  2. Ackman predicted brain-computer interfaces are a major era, citing Neuralink's $42 billion secondary valuation and his Precision Neuroscience investment.
  3. He opposed Mayor Mamdani's policies, saying they scare away productive New Yorkers and drive up costs.
  4. Ackman supports the president's war with Iran, calling it necessary despite short-term energy price inflation.

Numbers and commitments

FigureWhat it refers toTypeAt
$300 million real estate acquired for institute metric 7:06
$700 million total investment including real estate commitment 7:06
3.4-acre campus size in New York City metric 10:24
$191 million price paid for biotech building price 10:24
2.5 million square feet potential buildable area on site metric 10:24
$42 billion Neuralink secondary market valuation metric 13:42
$250 million Precision Neuroscience funding round commitment 13:42
$1,000 initial funding per American in 401(k)-style plan commitment 27:14

Chapters

  1. 0:00Opening about jury duty and design
  2. 3:44Lucy's brain hemorrhage and recovery
  3. 6:52Institute investment and real estate details
  4. 7:24Critique of healthcare system
  5. 10:24Institute vision and partnerships
  6. 13:42Brain-computer interface investments
  7. 16:37New York City and Mayor Mamdani critique
  8. 23:01Economy, Iran war, and AI impact
  9. 28:25Healthcare model and patient care approach
  10. 33:29Critical minerals and space mining

Questions asked in this interview

12
  1. 0:59Well, how do you feel about jury duty, Bill?
  2. 2:29What have you learned about design as a result of that proximity?
  3. 9:05All right. So, what's the solution?
  4. 13:15I realize it's a blended nonprofit-for-profit approach, but if brain science were such a good business, wouldn't a venture capitalist have backed it already?
  5. 16:37How do we square these two?
  6. 18:55Have you met with Mayor Mamdani?
  7. 18:59Would you meet with him if he reached out?
  8. 19:03Do you have an understanding of why the mayor resonated with so many young New Yorkers?
  9. 23:01And going back to what we talked about with affordability, are you worried about the American consumer starting to tighten belts?
  10. 25:53Is there anything about the president's agenda — and you were a very vocal supporter of him — that you disagree with?
  11. 26:37I will — and I'm just going to pick on a couple of people. Is that Adam back there?
  12. 28:25And what success may look like for you maybe five years from now, ten years from now?
Interviewer 0:17 ↗
Good afternoon everyone, or I guess good evening. Let's get right into it. So in 2009, somewhat controversially, Fast Company put a bold, unpredictable business leader on the cover of its print magazine. This individual would go on to become a household name in many circles, straddling the worlds of business, the Ivy League, and even Page Six. That person is not on stage with me today. That is Neri Oxman, the former MIT Media Lab Fellow and co-founder of the Oxman Design Studio. Neri was unable to join us today because of an unavoidable conflict, but...
Bill Ackman 0:58 ↗
Jury duty.
Interviewer 0:59 ↗
Oh, we can say that. Well, how do you feel about jury duty, Bill?
Bill Ackman 1:02 ↗
I think it's an incredibly important civic responsibility.
I'm totally serious. One of my amazing life experiences was I was selected to be on a jury for someone who was accused of rape, and it was an amazing — there should be a movie about that experience. But in all seriousness, I try to get on juries, but they don't want me anymore. But back then they took me, so.
So Neri was like, 'Oh, well, this is a waste of time.' I said, 'No, it's going to be like one of the most important things you do.' And by the way, why? Because someday you may find yourself accused of a crime you didn't commit. And having people who take this seriously is like one of the most important things. So, you know, next time you get jury duty, it's really a good thing.
Interviewer 1:51 ↗
I concur. I served on jury duty right when I moved to New York and it is an amazing — it's like all walks of life. Everyone on my jury took it very seriously. But we're not here to talk about jury duty. We were originally going to talk about design. I'm not going to hold Bill to the same standard I would have held Neri to. By the way, this is the cover of Fast Company that Neri was on. That is for you. For your collection.
Bill Ackman 2:25 ↗
She's hot.
Interviewer 2:29 ↗
But it is interesting to me, Bill, and what we had planned to talk a little bit about, had Neri been able to be here, was the relationship between business and design, and your relationship and your institutions straddle that world. The Oxman Design Lab is in the same building as the Pershing Square Capital Management offices. What have you learned about design as a result of that proximity?
Bill Ackman 2:58 ↗
So I've always — you know, Neri makes fun and she says, 'Bill, you're a better architect than I am.' I always cared a lot about architecture. I focus less on design, but obviously in the last nine years of knowing Neri, it's something I've spent a lot of time on. Design is unbelievably important and powerful and a huge driver of our reputation, perception. So I think it's really, really important and we're, you know, we're building something right now and we're just in the process of like everything from a logo to, you know, presenting ourselves to the world and it makes a huge difference. So I probably under-appreciated the importance of design in the pre-Neri world. Yeah.
Interviewer 3:44 ↗
You've generously agreed to talk a little bit about this new thing that you're building, and it started with an admittedly sensitive subject, which is that your daughter Lucy suffered a brain hemorrhage and spent weeks in a coma. First of all, I have to ask how she's doing.
Bill Ackman 4:01 ↗
You know, I think she's doing well. You know, it's certainly compared to where she started. So her story is a massive brain hemorrhage due to a congenital weakness we were unaware of. She lived alone in Williamsburg, you know, a few years out of college. You know, the really unfortunate part is that we didn't find her for, you know, 15 to 19 hours after the incident took place before we could release the pressure on her brain. And most people who start in that circumstance, they either don't do the surgery because they think you're too far gone, or if they do the surgery, you know, you don't survive, or you survive three months in a nursing home and you die of pneumonia. So it was not a great place to start. And I can tell you today she's the same old person that she was before. Cognitively she's, I think, fine. She has the same sense of humor. Yeah.
But she's learning to walk again. She's learning to speak again. And she's hopefully learning to see again. So, you know, she's got a long way to go. But we make progress almost every day. We have a call with her doctors every day and her care team. And we do that at 4:00. So it was on the way here. And she had a great day. So every time she has a great day — it's not a perfect, it's not a straight line. But, you know, as I tell her, and, you know, for years I've been like talking to, you know, college students, whatever, I go and speak on campus about, you know, here's, you know, the nature of life is it's not a straight line up. You're going to have some kind of event. It could be you get fired, your startup crashes from a billion-dollar valuation to zero, you get divorced, your girlfriend leaves you, you have a major health incident, something like this happens. And the key is just as you work your way out of it, just make a little progress every day. Progress compounds. Well, she's a classic example of how important that is because if, you know, she — the good news about, you know, cognition is that she's coming back. The bad news is she understands her circumstance. And so emotionally, this is an unbelievably challenging thing and it just seems like the road's incredibly far and you're so close to it, you don't see the improvements. But people who didn't see her for a week or two weeks and they come back, you know, they notice, you know, the progress. So we just know the power of compounding. The way compounding works is it's a — I'll do it, you know, it's a line that you don't see much progress until eventually it goes vertical. Just like, you know, kind of the COVID thing where you don't notice it until it's everywhere. And she's still in this phase. She's not yet here. But she's going to get there. And, you know, we're in the fortunate position to be able to throw everything at her. And this is the best time in history to have a brain injury because of technology, brain-computer interfaces, AI, all these things are going to be very helpful to her recovery and to other people similarly situated.
Interviewer 6:52 ↗
So based on her experiences, you announced a $400 million pledge to create what you've called the world's greatest brain research, rehabilitation, recovery, and human optimization and longevity institute.
Bill Ackman 7:06 ↗
Two things. It's not a pledge. We've already invested the money in the institute. And two, we've acquired about $300 million in real estate. So we're in now for about $700 million. And, you know, I feel very fortunate to be able to be, you know, whatever it takes with respect to this project.
Interviewer 7:24 ↗
Talk a little bit about how you think that health care should be redesigned as a result of what you've been through with Lucy.
Bill Ackman 7:35 ↗
Sure. I'm sure everyone here has had some experience with the health care system — a parent, a challenge, a child. And, you know, the problem: many health care systems are nonprofit. While philanthropy, nonprofit sounds like good, I'm a big believer if there's a for-profit solution to a problem, that's a much better solution. Now, for-profit health care also has its own sort of challenges, but, you know, the system is completely broken. The incentives are a disaster. The way reimbursement works, you know, like crazy stuff like, 'Well, we won't pay for the fMRI scan unless she's an outpatient.' Because — or we can't, you know, if you do the surgery and then you have this follow-on procedure, they'll only reimburse one number for the whole thing. So, you know, you have to wait a month between the two things or she has to check out of the hospital to get — I mean, it's crazy. The approach we've taken is, you know, we don't care about insurance reimbursement. We'll deal with that later. But very few people can be in that circumstance. So the system is fundamentally broken. The incentives are poorly designed. There's enormous waste. Now, on the other side of it, you have a lot of incredibly well-meaning, hardworking, intelligent people doing their best to deliver care in that environment. I could not be more effusively positive about, you know, the nurses, the doctors. You know, so you've got all these great people in a completely effed-up system. That's what we're — that's the state of health care in the United States.
Interviewer 9:05 ↗
All right. So, what's the solution?
Bill Ackman 9:08 ↗
So the solution is a complete reboot. You know, what we're doing here is, one, New York City happens to be a really good place to build a health care — you know, to redefine health care. And the benefit of having independent financing coming from one source is we can make decisions like a startup. You know, imagine a startup where you've got one big investor, you're not worried about having to raise money. You can focus on recruiting the best people. And, you know, I'm a business person. You know, I come to this with a bunch of skills that are helpful: recruiting, picking talent, designing incentives, real estate, business formation, all those things we're applying here. And, you know, I've been very fortunate in identifying a couple of super talented senior leaders here that are inspired by what's possible. We haven't announced them yet, so I'll keep their names confidential. We then — you know, I've got a good Twitter platform. So instead of hiring a search firm...
Interviewer 10:16 ↗
On Twitter?
Bill Ackman 10:17 ↗
What's that? Okay. See, there's still opportunities for more followers.
Interviewer 10:21 ↗
Learn something new every day.
Bill Ackman 10:24 ↗
By the way, I'm just shy of three million, so if we get grouped together, you know. The way we're doing it, you know, I basically put out a tweet saying, 'Here's what we're doing. If you're interested, let us know.' You know, I don't know what the number is, but we've got 1,500 incredibly high-quality expressions of interest. We're going through every one of them. We're getting back to everyone. This is something inspiring because almost everyone's had someone in the family with Alzheimer's, MS, a brain injury, a stroke, you know, a need for rehabilitation and have been dissatisfied with, you know, what's available. And we were kind of lucky in terms of timing or divine intervention. An incredible piece of real estate. You know, it's hard in New York City to get good real estate. We have a 3.4-acre campus on 65th, 66th on 11th Avenue. How about with views of the water? I mean, it's an incredible piece of real estate. Bought it for nothing. It was a — no, seriously, they spent $650 million building a 400,000-square-foot biotechnology building. We paid $191 million for the building. We bought it from Apollo, who was the first mortgage lender. The rest of the site we have under contract. It's the Saturday Night Live studio building, which we're — you know, don't tell Saturday Night Live yet, but we're going to tear that down. They'll probably do an episode about me when we tear down the building. And then we have, you know, a couple of additional acres. We do need the city to upzone it, which they've been doing for sites along 11th Avenue as part of the City of Yes program. But we have potentially two and a half million square feet of buildable area where we're going to bring a ton of jobs. And the other thing that's kind of cool is in addition to inbound from people who want to work there, we've had, you know, every brain-computer interface company, everyone adjacent in the rehabilitation space, you know, Columbia, NYU, Northwell, Mount Sinai have all reached out, want to collocate with us. And, you know, there are real synergies to be created kind of by doing this. So we're kind of, I think, optimizing from the best of nonprofit finance to, you know, kind of for-profit. We're going to have, you know, a Y Combinator-type accelerator. We're going to have a venture fund to help, you know, back these companies. We're going to help them succeed. We may have a for-profit AI affiliate. You know, if you think about AI, what do they need? They need training data. The brain is an unbelievable generator of data. We have not yet tapped that source of training data. These various hospitals have amazing scanning and patient and sample data that we can, you know, consolidate and leverage. And we're going to learn a lot and we're going to do it in a, you know, a Fast Company, you know, approach to business building. So, you know, super excited about it.
Interviewer 13:15 ↗
Well, thanks for the Fast Company shout-out. But you had said to the Wall Street Journal last year that one of your criticisms of nonprofits is that, you know, if there isn't a for-profit answer, a venture capitalist wouldn't back it. I realize it's a blended nonprofit-for-profit approach, but if brain science were such a good business, wouldn't a venture capitalist have backed it already?
Bill Ackman 13:42 ↗
And they are. I mean, Neuralink has like a $42 billion valuation in the secondary market. We were leading a round of financing for a company called Precision Neuroscience. You know, they just — we'll let them make their own announcement, which they're going to do shortly, but they raised, you know, $250 million, you know, billion-plus post-money valuation. This is the era of brain-computer interfaces. It's not just Neuralink. There are a dozen companies doing super interesting stuff. Neuralink is one of the more invasive technologies. I'm particularly interested in the sort of less invasive technologies, but just recording what's going on in the brain. There's just a lot of really cool stuff kind of going on. The benefit here of nonprofit is the nonprofit institutions get a little squeamish about doing business with a for-profit enterprise. So I think it's just easier for us to do business with Columbia and NYU and these others in the context of, you know, so we're going to do our best to get the best of nonprofit-for-profit. Obviously, any profits that are made here — and by the way, we have a big profit on the real estate. You know, with an upzoning we can see the site is worth, you know, approaching a billion and a half dollars and we're paying — we paid a fraction of that. Any profits, you know, part of it's going to be a high-rise residential condominium. God bless. And the profits from the land sale, you know, we will reinvest obviously in the institute. So we're — you know, one of the things, you know, I hope no one in the room has had a child with a health issue. Unfortunately, I suspect that some of you have. Unless none of you have children because this is that generation. But you should, you know, go and copulate. It's a really important thing. Without birth control.
Interviewer 15:32 ↗
That's going to be the headline of the session. 'Go and copulate,' says Bill Ackman.
Bill Ackman 15:36 ↗
We need another generation. Now, what was my point? Once I got to copulate, I lost my train of thought.
But the profit, nonprofit — no, we did that already. Wow, interesting. Maybe I need to check into the brain institute. That's true. But how did I get to children and sex? I'm not sure exactly where that got in there.
Interviewer 16:11 ↗
Boy, this is like becoming an interactive session. I've completely lost control of the conversation.
Bill Ackman 16:22 ↗
All these things are true.
Interviewer 16:24 ↗
All right, let's move on. But because I — the real estate...
Bill Ackman 16:28 ↗
is a very complicated thing. Okay, go ahead.
Interviewer 16:31 ↗
Oh, and by the way, for all of you who are shouting out questions, Bill is going to take a couple of questions at the end of the session.
Bill Ackman 16:36 ↗
I'll take more than a couple.

30 more exchanges in this transcript

Sign in free to read the rest of this interview. No card required.

Sign in to read the full transcript

Cite this transcript

APA, MLA, BibTeX
APA

Ackman, B. (2026, September 21). The Business of Design—and the Design of the Future [Interview transcript]. Fast Company. CEOInterviews.AI. https://ceointerviews.ai/interview/3008456/

MLA

Bill Ackman. "The Business of Design—and the Design of the Future." Fast Company, 21 Sep. 2026. Transcript, CEOInterviews.AI, https://ceointerviews.ai/interview/3008456/.

BibTeX
@misc{ackman2026_3008456,
  author       = {Bill Ackman},
  title        = {The Business of Design—and the Design of the Future},
  howpublished = {Interview transcript, Fast Company. CEOInterviews.AI},
  year         = {2026},
  month        = {sep},
  url          = {https://ceointerviews.ai/interview/3008456/},
  note         = {Speaker-attributed transcript with timestamps}
}