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John Lechleiter on enterprise risk management

From Learning from Legends: Dr. John Lechleiter (former CEO of Eli Lilly) · · Citizen 7

“If you were to take a look at all the 2x two matrices generated on this enterprise risk management uh exercise by all the Fortune 500 companies just last year in 2019... you would almost guarantee you that nowhere on any of those 2x two matrices would you have found pandemic listed. Okay? And yet in many ways it was entirely predictable.”

John Lechleiter
Former Chairman, President & Chief Executive Officer, Lilly (Eli)
Controversial Policy Impact enterprise risk managementpandemic preparednesscorporate governance

On , John Lechleiter, Former Chairman, President & Chief Executive Officer at Lilly (Eli), spoke about enterprise risk management during Learning from Legends: Dr. John Lechleiter (former CEO of Eli Lilly) on Citizen 7.

Learning from Legends: Dr. John Lechleiter (former CEO of Eli Lilly)
Watch on YouTube at 8:18
Learning from Legends: Dr. John Lechleiter (former CEO of Eli Lilly)
Citizen 7
Watch on YouTube at 8:18
Aug 25, 2020 We were thrilled to host a special Zoom discussion with Dr. John Lechleiter, former Chairman and CEO of Eli Lilly and Company, on Tuesday, August 25, 2020. John was a perfect candidate to launch our “Learning from Legends” series of discussions. His commitment to our city and leadership across his business, civic, family, and educational responsibilities is truly legendary. We are grateful for all his work at Lilly and within our community. John is a fantastic communicator and we will enjoy this time with him as he shares some of his story and life’s lessons along the way. About Dr. John Lechleiter:  Dr. John Lechleiter retired as Eli Lilly’s president and chief executive officer on December 31, 2016, after more than 37 years of service. He served as chairman of Lilly’s board of directors from January 2009 through May 2017. Dr. Lechleiter joined Lilly in 1979 as a senior organic chemist in the chemical process research and development division. He became head of his department in 1982. He subsequently held roles in product development, project management, regulatory affairs, and pharmaceutical operations. In 2005, he was named President and Chief Operating Officer and joined Lilly’s board of directors. He became CEO on April 1, 2008. Dr. Lechleiter earned a bachelor’s degree in chemistry from Xavier University in 1975 and masters and doctoral degrees in organic chemistry from Harvard University. He has received honorary degrees from Marian University, the University of Indianapolis, the National University of Ireland, Indiana University, Franklin College, Purdue University, and Butler University. Dr. Lechleiter is a member of the American Chemical Society. He serves on Marian University’s President’s Advisory Council, the Dean’s Advisory Council for the IUPUI School of Science, the IU Fairbanks School of Public Health Advancement Council, the board of directors of the Hoosier Art Salon, and the SKL Advisory Council of the Stanley K. Lacy Executive Leadership Series. He is an honorary trustee of the Children’s Museum of Indianapolis and a member emeritus of the board of the Central Indiana Corporate Partnership. He also serves on the boards of Battelle, Ford Motor Company, Indiana Economic Development Corporation, Indiana Biosciences Research Institute, and Lilly Endowment, Inc. Dr. Lechleiter and his wife, Sarah Lueke Lechleiter, have three children, Daniel, Andrew, and Elizabeth, and nine grandchildren. In 2016, Dr. and Mrs. Lechleiter jointly received the Charles L. Whistler Award for service to the Indianapolis community. In 2017, they were each awarded the Sagamore of the Wabash by Governor Eric Holcomb. Dr. Lechleiter was inducted into the Indiana Academy in 2019 by the Independent Colleges of Indiana. 00:00 Welcome & Introduction to Citizen 7 03:13 Introducing Dr. John Licklider 06:38 Opening Reflections: Leadership Amid Pandemic 10:39 Reassessing Risk & Organizational Purpose 15:44 The Importance of Staying Mission Focused 21:07 Three Pillars of Good Leadership 27:13 Courage, Optimism, and Generosity Explained 34:44 Stories of Leadership in Challenging Times 41:45 Personal Roots of Courage & Generosity 46:07 Personalized Leadership: Habits and Communication 50:48 Opportunities and Generosity in Indianapolis 58:33 Key Habits & Growth as a Leader 01:01:32 Faith and Spiritual Reflections During Crisis 01:04:51 Book Recommendations & Final Thoughts 01:06:10 Upcoming Citizen 7 Events & Announcements 01:08:36 Closing Reflections and Prayer
John Lechleiter

About John Lechleiter

Former Chairman, President & Chief Executive Officer · Lilly (Eli)

John Lechleiter, former chairman and CEO of Eli Lilly, has remained active in public speaking and community engagement. In a 2020 discussion, he reflected on leadership during the COVID-19 pandemic, noting that enterprise risk management exercises at Fortune 500 companies in 2019 had not listed a pandemic as a risk. He also discussed Eli Lilly’s response to the loss of patents for products representing roughly 40% of 2009 sales, stating that the company chose to increase R&D investment despite falling revenue. Lechleiter expressed support for Indiana’s school voucher system, describing it as a “fairly progressive approach” to educational choice, and mentioned the Central Indiana Community Economic Relief Fund, which raised $23 million for pandemic relief. In a 2024 commencement address at Xavier University, his alma mater, Lechleiter urged graduates to be discerning, kind, generous, and courageous. He emphasized the importance of independent thinking and resisting the tendency to follow the crowd. In a 2025 TEDx talk, he discussed the concepts of mavericks, icons, and geniuses, citing figures such as Elon Musk, Steve Jobs, and Mother Teresa, and described his own role at Eli Lilly as an opportunity to contribute to the company’s mission of developing life-saving medicines. He also appeared in a 2024 video honoring the John C. Lechleiter Award, which recognizes Eli Lilly’s partnership with Providence Cristo Rey High School, a work-study program he helped establish.

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