Ralf Kuriyel on inline flow VPX
From Go with the Flow II Expert Panel Discussion | Hosted by Ralf Kuriyel, Repligen (10/27/22) · · Repligen
“Using inline flow VPX instruments allows us to safely and consistently push drug substance concentration to the highest levels without risking critical quality attributes, which is critical for GMP manufacturing and process consistency.”
On , Ralf Kuriyel, Senior Vice President of Research & Development at REPLIGEN CORP, spoke about inline flow VPX during Go with the Flow II Expert Panel Discussion | Hosted by Ralf Kuriyel, Repligen (10/27/22) on Repligen.
About Ralf Kuriyel
Ralf Kuriyel, Senior Vice President of Research & Development at Repligen, hosted a panel discussion on October 27, 2022, as part of the "Go with the Flow II" expert webinar series. During the session, Kuriyel stated that Repligen is "passionate about pushing our automated systems marrying it with the proper PAT tools" with the goal of providing solutions that make manufacturing less expensive. He also noted that the company is "still in the research, in developmental stage" regarding further uses of flow VPX technology. The panel discussion covered topics including process analytical technology (PAT) and future perspectives on PAT in biologics manufacturing. Panelists discussed the use of inline flow VPX instruments for real-time monitoring of protein concentration during ultrafiltration/diafiltration processes. Challenges discussed included method transfers between groups, building trust in PAT for GMP manufacturing, and the need for stakeholder alignment and training when implementing new technologies.