Glaukos - Tomas Navratil, Chief Development Officer
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Chief Development Officer, Glaukos
Search every verified Tomas Navratil interview, podcast appearance, and on-the-record quote — each transcript cross-checked by AI and human review to confirm speaker identity. Tomas Navratil, Chief Development Officer at Glaukos, presented an update on the company’s research and development strategy at an industry event in September 2023. He discussed recent regulatory clearances and clinical trial results, including the 510(k) clearance of the iStent infinite, which he described as the first standalone administration of a trabecular bypass device. Navratil also highlighted positive Phase 3 results for the iDose TR travoprost implant, noting that in two studies involving over 1,100 patients, 93% were well controlled at 12 months after a single dose on the same or fewer topical medications, and 81% were medication-free. He characterized the safety profile as showing no serious corneal adverse events and a hyperemia rate of 3%, which he said was more than tenfold lower than that associated with topical travoprost. Navratil stated that Glaukos’s R&D strategy is based on five therapeutic platforms, which he said are capable of generating therapies for glaucoma, dry eye disease, presbyopia, keratoconus, age-related macular degeneration, diabetic macular edema, retinal vein occlusion, and other ophthalmic conditions. He noted that the company’s near-term pipeline includes the iDose TR in a pre-NDA stage and a second-generation product, iDose TREX, with twice the payload. Navratil attributed the company’s progress to support from patients and clinicians, and said Glaukos is preparing for future growth following recent approvals and positive study results.
“Glaukos was initially created with the intent on transforming glaucoma therapy and Innovation is truly at the heart of everything that we do at Glaukos.”
“This effort led to a creation of new medical device class, the tropical bypass devices or makes the first in class product I stand and ultimately the global mix Marketplace.”
“The R&D strategy for future growth and value creation is really based on utilizing these technological platforms, each of which alone has the potential of spawning multiple paradigm shifting products and are they able to be then leveraged in our scalable commercial platform.”
“The iDos is a miniature implant implanted in the anterior segment of the eye and capable of eluting multiple years of pharmacotherapy into the anterior segment.”
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