Vice President of Early Discovery Research, Genentech, Roche Holding AG
Search every verified Vishva Dixit interview, podcast appearance, and on-the-record quote — each transcript cross-checked by AI and human review to confirm speaker identity. Vishva Dixit, Vice President of Early Discovery Research at Genentech, has continued to discuss his research on cell death mechanisms in recent appearances. In a July 2024 podcast episode, he explained the distinction between apoptotic and necrotic cell death, noting that apoptosis is non-inflammatory while necrosis triggers inflammation. He also discussed his work on necroptosis and pyroptosis, including a small molecule inhibitor targeting RIPK1 and research on gasdermin D's role in septic shock, which he described as responsible for 8 million deaths annually. In a May 2024 lecture, he presented on "Why So Many Ways to Die?" and discussed the potential of inhibiting gasdermin D to blunt cytokine storms associated with diseases like sepsis and COVID-19. Dixit has also reflected on his career trajectory and scientific philosophy. In a November 2023 interview, he discussed growing up in colonial Kenya, attending medical school at the University of Nairobi, and his views on science education, stating he favors a liberal arts approach and would do away with most AP classes. He has described his research focus on understanding how cells die, including his earlier work identifying caspases as components of death receptor-induced apoptosis pathways, and more recent discoveries involving the protein ninjurin-1 in membrane rupture during cell death.
The lifecycle of a cell mirrors our own lives – cells live and die as we do. It would be easy to think of cell death, or apoptosis, as a negative action, but the death of a cell is actually critical to many of the important biological functions that keep our bodies running. Learn more about the mysteries behind cell death from Vishva Dixit, M.D., Vice President, Physiological Chemistry.
Dr. Vishva Dixit, M.D., presents the UAB Pathology 2024 Pritchett Lecture, "Why So Many Ways to Die?" May 23, 2024.
In this interview, Vishva Dixit, MD, talks with Neil Greenspan, MD, PhD, senior editor of Pathogens and Immunity about what his career in science has revealed about biology in humans, but also what it has revealed about how to be successful in science. Dr. Dixit is a world-famous immunologist and biochemist who has made major contributions in the study of innate immunity and, particularly, in aspects related to inflammasome activation. He is vice president and senior fellow in physiological chemistry at Genentech.
Vishva M. Dixit is Vice President of Discovery Research at Genentech. A pathologist by training, he has studied molecular mechanisms that underlie cell death and inflammatory signaling. In particular, he is known for the breakthrough discovery that a cysteine protease (caspase) is a component of the death receptor-induced apoptotic pathway - a finding that allowed his laboratory and others to then elucidate the entire 'death cascade'. Vishva was born in Kenya in 1956 and became a US citizen in 1987. He went to medical school at the University of Nairobi and, after clinical work at the Kenya…
On any given day, over 50 billion of the cells in your body will die. The question of how we live while our cells are continuously dying has captivated Dr. Vishva Dixit. After a long career in academia, Dixit rose through the ranks at Genentech and currently serves as the Vice President of Early Discovery Research. His scientific work has focused on the elucidation of the mechanisms of apoptosis, including the discovery of caspases.
Ignite Life Science Foundation, Cactus Communications, and IndiaBioscience have come together to co-host this live online event. In a relaxed and conversational format, the interlocutor for each session will uncover the background story of the work and life of an eminent scientist. This will not only afford students, young scientists, and the science-curious in India a first-hand/ringside view of what it takes to become successful in science but also give them an opportunity to direct questions to the invited scientist. This is a platform for students, young scientists, and the science-curious…
Dr. Dixit, vice-president of Genentech talks to CDD Press at the recent meeting in Capri, Italy. He describes his work on mechanisms of cell death.
Walter and Eliza Hall Institute Centenary seminar series 17 November 2015 Dr Vishva Dixit Genentech, US Introduced by Professor Andreas Strasser
Vishva Dixit, Vice President of Physiological Chemistry at Genentech talks to Barry Whyte, EMBO Head of Public Relations & Communications, about cell death, cancer and inflammation and moving from academia to industry.
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