Skye CEO 2025 Year in Review
CEO Punit Dhillon discusses Skye's accomplishments in 2025 and execution plans for 2026.
Chief Executive Officer, Skye Bioscience
Search every verified Punit Dhillon interview, podcast appearance, and on-the-record quote — each transcript cross-checked by AI and human review to confirm speaker identity. Punit Dhillon, chairman and CEO of Skye Bioscience, discussed the company’s approach to obesity treatment in an October 2024 podcast appearance. He described Skye’s strategy of targeting peripheral CB1 receptors with an antibody-based therapy, contrasting it with small-molecule CB1 inverse agonists like Novo Nordisk’s monlunabant, which he said faced concerns over neuropsychiatric side effects. Dhillon stated that Skye’s approach aims to preserve lean mass, restore leptin sensitivity, and improve insulin sensitivity while promoting weight loss, and he emphasized that the company’s primary value driver is execution on its Phase 2 study. Dhillon also outlined what he considers key factors for success in the obesity therapeutics market, including demonstrating clinically meaningful weight loss, limiting adverse events, and offering a convenient dosing regimen for long-term use. He noted that the regulatory bar for FDA approval remains showing at least 5% weight loss sustained over a year, with comparisons typically made against placebo rather than active treatments. He added that addressing comorbidities and preserving lean mass are important considerations for payers and long-term patient adherence.
CEO Punit Dhillon discusses Skye's accomplishments in 2025 and execution plans for 2026.
Today’s guest is someone who’s seen biotech from both sides of the table—first as an investor, and now as a builder. I’m joined by Punit Dhillon, CEO of Skye Bioscience, where he’s leading one of the most exciting stories in metabolic health. Punit started Skye as employee number one and has since built it into a clinical-stage company with one first-in-class programs and backing from major life science investors like 5AM and Versant. With a background in finance and business development—and a career that includes partnerships with Merck, Genentech, BMS and Pfizer—he brings a unique and deepl…
A conversation between Skye CEO Punit Dhillon and Dr. Beverly Tchang, MD, before their panel at SXSW 2025.
CEO Punit Dhillon talks about Skye's accomplishments in 2024 and key plans and milestones for 2025.
While the trend toward CB1 inhibition for obesity took a small hit with the release of Novo Nordisk's small molecule oral cannabinoid receptor (CB1) inverse agonist monlunabant last month, Skye Bioscience Chairman and CEO Punit Dhillon is shaking it off. He's confident that his company's antibody-based approach to CB1 inhibition will make a moot point of the neuropsychiatric side effects that put a damper on Novo's data. On this episode of the Business of Biotech, we're digging into the uber-hot business of weight loss therapeutics and going deep with Dhillon on why Skye's blood/brain barrier-…
This episode features an interview with Punit Dhillon, Chairman & CEO of Skye Bioscience (https://skyebioscience.com/) , a pharmaceutical company developing proprietary molecules to treat diseases involving inflammatory, fibrotic and metabolic conditions. Skye Bioscience is at the forefront of exploring the endocannabinoid system for drug development. Punit brings two decades of experience as a leader and investor within the life sciences sector. During the interview, he shared his journey leading up to his role at Skye Bioscience and how his previous experiences have shaped his vision for…
Skye Bioscience Acquisition of Bird Rock Bio Conference Call Skye CEO Punit Dhillon and CFO Kaitlyn Arsenault discuss a strategic transaction and financing, and Skye’s path forward. 🔍 *Key Points:* Introduction by Bernie Hertel, Head of Corporate Communications. Punit Dhillon, CEO, shares Skye's progress since 2020, updates on SBI-100 OE, and discusses the acquisition of Bird Rock Bio and its novel complementary technology. Kaitlyn Arsenault, CFO, elaborates on the financial details, the impact of the $17M raise, and potential uplisting. Punit Dhillon wraps up with a perspective on the val…
Interview Punit Dhillon, the President, CEO & Chair of Skye Bioscience Inc In this episode, I interview Punit Dhillon, the President, CEO & Chair of Skye Bioscience Inc. based in San Diego, California, USA, a public pharmaceutical company with a leading program in ophthalmology, developing a drug for glaucoma. Punit is a biotech and life sciences entrepreneur passionate about helping the community. He’s also an author of the book Catapult wherein he shares 10 principles for a purpose-driven life and career, linking together the athletic strengths that will help people succeed in the business…
#skyebioscience #skye In this video, I had the pleasure to interview with the CEO of Skye Bioscience Punit Dhillon. Learn more about what Skye is doing in this video! Thanks for watching and appreciate the support!
Punit Dhillon, CEO of Skye Bioscience, gives an overview of his company to potential shareholders at Strategic Investment Insights, May 7th, 2022. To learn more about Skye Bioscience, please visit their website https://skyebioscience.com/. Make sure to Subscribe to this channel and join our mailing list at https://strategicinvestmentinsights.com/.
Punit Dhillon, CEO of Skye Bioscience, gives an overview of his company to Chris Temple, editor and publisher of The National Investor. Punit will be presenting Skye Bioscience at Strategic Investment Insights on May 6th & 7th, 2022. Register for the conference today at https://strategicinvestmentinsights.com/ .
Punit Dhillon is the chairman and CEO of Sky Bioscience. He's an entrepreneur, keen athlete, an author of the book, Catapult: How to Think Like a Corporate Athlete to Strengthen Your Resilience. Learn about how Punit’s athletic approach to live has helped catapult his business including: Growing up as an athlete he noticed the parallels in corporate life. The components of a corporate athlete. What mindset has to do with growth as a leader. How to live by true accountability and be purpose driven. Join our Tribe at https://leadership-hacker.com Listen in to learn more!
Sign in to search the full transcript archive, filter by topic, and access every quote from Punit Dhillon.
The summary and quote tags on this profile are produced with AI assistance from verified, first-person interview transcripts, then checked by our team to confirm the speaker's identity and the accuracy of every quote. See how we verify →
Pro unlocks every transcript in full, plus unlimited search across every executive and company we cover.
50% off appliedPulling data at scale? The Data API gives you 30,000 transcripts a month over REST, MCP and JSON.
Compare all plans