CEOInterviews.AI
Start App
Try: AI strategy tariffs earnings guidance layoffs interest rates growth

Brian Culley

Chief Executive Officer, Lineage Cell Therapeutics

Search every verified Brian Culley interview, podcast appearance, and on-the-record quote — each transcript cross-checked by AI and human review to confirm speaker identity. Brian Culley, CEO of Lineage Cell Therapeutics, discussed the company's progress in cell therapy during a June 2024 podcast appearance. He highlighted the company's allogeneic approach, which involves manufacturing cells for off-the-shelf use, contrasting it with bespoke autologous therapies that he described as inefficient and costly. Culley also referenced a collaboration and license agreement with Roche and Genentech, noting the credibility and capabilities such a partnership brings, and mentioned undisclosed programs that he said contribute to his optimism about the company's pipeline. In an earlier December 2020 appearance, Culley described how Lineage navigated clinical trials during the COVID-19 pandemic, including for OpRegen (dry age-related macular degeneration) and OPC1 (acute spinal cord injury). He credited having trial sites in both the U.S. and Israel, which were affected by lockdowns at different times, and said the company opened additional sites to increase opportunities. He also noted that the pandemic prompted regulatory flexibility, though he was uncertain whether such changes would persist beyond COVID.

Recent appearances

  • Building “Off-the-Shelf” Regenerative Cell Therapies: The Next Biotech Revolution | Brian Culley

    Today’s conversation sits at the intersection of one of the most ambitious - and most challenging - frontiers in modern medicine: regenerative cell therapy. For decades, the vision has been incredibly compelling - replace damaged or dying cells with healthy ones, and you could potentially restore function in diseases like macular degeneration, spinal cord injury, hearing loss, and even Type 1 diabetes. But while the science has advanced, the field has consistently run into a different kind of barrier: how do you actually manufacture living cells as consistent, scalable, affordable therapies?…

    Watch on YouTube ↗

  • Allogeneic cell therapy isn’t dead, with Brian Culley

    So far, allogeneic, or “off the shelf”, cell therapy has failed to produce the kinds of results that autologous cell therapy has. But biotechs haven’t given up on allo, which promises easier distribution and administration than therapies that require modifying cells at the bedside. At Lineage Cell Therapeutics, CEO Brian Culley has been working for many years on allogeneic cell therapies across a range of indications, the most far along being a potentially practice-changing therapy for macular degeneration. In an interview on the sidelines of JP Morgan in San Francisco, Culley described…

    Watch on YouTube ↗

  • Advancing Allogeneic Cell Therapy for SCI and Blindness with Lineage's Brian Culley

    On episode 114 of Cell & Gene: The Podcast, Host Erin Harris talks to Brian Culley, CEO of Lineage Cell Therapeutics, about advancing cell therapy beyond oncology and into transformative treatments for conditions such as spinal cord injury and blindness. Culley shares how Lineage’s allogeneic, off-the-shelf approach, anchored by its OPC1 program, aims to replace lost or damaged cells to restore function, starting with patients who have plateaued after chronic spinal cord injury. He details the DOSED study’s innovative delivery device and thaw-and-inject formulation, both designed to simplify a…

    Watch on YouTube ↗

  • Can Cell Therapy Reverse Hearing Loss? Development of Lineage Cell Therapeutics ReSonance™ Program

    Can cell therapy revolutionize hearing loss treatment? In this follow-up discussion, Brian Culley, CEO of Lineage Cell Therapeutics, shares the latest updates on the ReSonance™ (ANP1) program, a pioneering preclinical study exploring auditory neuron cell transplantation. Culley explains how lab-grown auditory neurons are being delivered to the inner ear to potentially restore damaged auditory pathways—a groundbreaking approach that could even complement existing treatments. In this conversation, Culley sheds light on the preclinical results, including the successful delivery of auditory neuro…

    Watch on YouTube ↗

  • Revolutionizing Medicine with Cell Therapy: Brian Culley, CEO of Lineage Cell Therapeutics

    Can cell therapy provide a real solution for spinal cord injuries, as well as vision and hearing loss? In this episode, Solomon Wilcots speaks with Brian Culley, CEO of Lineage Cell Therapeutics, about how their groundbreaking work is creating new possibilities for patients. Brian shares how replacing damaged cells with healthy ones is transforming the recovery process. Discover Lineage Cell Therapeutics’ latest advancements and how they could reshape the future of medicine.

    Watch on YouTube ↗

  • C&G Regulatory Guidance with Lineage Cell Therapeutics' Brian Culley

    When we last caught up with Brian Culley, CEO of Lineage Cell Therapeutics, it was January, 2021. A pandemic was raging. His company was moving mountains to keep its OpRegen dry AMD clinical trial together, and did so despite lockdowns that kept a largely aged patient population from setting foot anywhere near a healthcare clinic. Lineage emerged stronger, signing a collaboration and license agreement with Roche and Genentech later that year. In May of this year, it doubled down on the commitment with a new services agreement with Genentech to support the OpRegen program. All this, while simul…

    Watch on YouTube ↗

  • Manufacturing Auditory Neurons with Brian Culley, CEO of Lineage Cell Therapeutics.

    The idea of manufacturing auditory neurons that can be used to replace those damaged by disease is closer to reality that you may think. This week, Brian Culley, CEO of Lineage Cell Therapeutics discusses a collaboration with the University of Michigan with an initial focus of studying cell therapy for auditory neuropathy spectrum disorders, a condition that affects about 10% of children with hearing loss. Be sure to subscribe to our YouTube channel for the latest episodes each week, and follow This Week in Hearing on LinkedIn and Twitter:   / this-week-in-hearing     / weekinhearing   Aud…

    Watch on YouTube ↗

  • #344 - Brian Culley, CEO at Lineage Cell Therapeutics

    Our Guest: Brian Culley, CEO at Lineage Cell Therapeutics What you'll get out of this episode: 📚 Culley's background and how he got to Lineage 🔬 Lineage’s technology platform and what it means to be an allogeneic, off-the-shelf, cell therapy company 🏥 The competitive advantages to this approach - specifically, manufacturing, and patient access 🥼 Lineage’s current clinical programs in development and the latest advancements 🥇 Milestones for Lineage Our sponsors for this episode are Sage Growth Partners & FlipMD Sage Growth Partners accelerates commercial success for healthcare organizations…

    Watch on YouTube ↗

  • Lineage Cell Therapeutics

    Brian Culley, CEO Carlsbad, CA (NASDAQ: LCTX)

    Watch on YouTube ↗

  • Fireside Chat – Lineage Cell Therapeutics (LCTX) CEO Brian Culley

    Originally broadcast LIVE August 23, 2022. Lineage Cell Therapeutics CEO Brian Culley is joined by Noble Capital Markets Senior Research Analyst Robert LeBoyer for a Q & A session featuring questions asked by the live audience throughout the event. Research, News, and Advanced Market Data on LCTX is available at no cost on Channelchek: https://www.channelchek.com/company/LCTX Information on upcoming live virtual roadshows is available on Channelchek: https://www.channelchek.com/vrs About Lineage Lineage Cell Therapeutics is a clinical-stage biotechnology company developing novel cell th…

    Watch on YouTube ↗

  • Interview with Brian Culley, CEO of Lineage Cell Therapeutics

    Creator and Host of BioTech IQ Ammon Rivera sits down with Lineage Cell Therapeutics CEO, Brian Culley. Interview originally recorded on June 7th 2022. Lineage Cell Therapeutics is tackling multiple indications including non-small cell #lungcancer #geographicatrophy #spinalcordinjury #auditory neuropathy. Catch episode 50 with Brian on the BioTech IQ podcast here - https://thebiotechiqpodcast.com/can-l... For more on #BioTech IQ - https://thebiotechiqpodcast.com/ Follow us on #linkedin -   / 8199.  . Connect with me -   / ammonr   For more on Lineage Cell Therapeutics - https://lineag…

    Watch on YouTube ↗

  • Cell Therapy Treatment for Hearing Loss: Interview with Lineage Cell Therapeutics CEO, Brian Culley

    This week we tackle cell and gene therapy for hearing loss. To help us better understand the potential of allogeneic cell therapy we asked Brian Culley, CEO of Lineage Cell Therapeutics to describe how it works and how these types of pharmacologic treatments could stand side-by-side existing treatments such as hearing aids and cochlear implants. Read more about Lineage, Sensorion and other pioneering companies at the forefront of hearing restoration and hearing loss prevention: https://hearinghealthmatters.org/ther... Interview transcript here: https://hearinghealthmatters.org/this... Be su…

    Watch on YouTube ↗

The summary and quote tags on this profile are produced with AI assistance from verified, first-person interview transcripts, then checked by our team to confirm the speaker's identity and the accuracy of every quote. See how we verify →