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John Evans

Chief Executive Officer, Beam Therapeutics

Search every verified John Evans interview, podcast appearance, and on-the-record quote — each transcript cross-checked by AI and human review to confirm speaker identity. John Evans, CEO of Beam Therapeutics, discussed the company's work in base editing technology during a September 2021 podcast appearance. He described base editing as a more precise alternative to earlier gene-editing tools like CRISPR, zinc fingers, and TALENs, noting that these first-generation tools solved the problem of targeting specific locations in the genome. Evans also addressed the challenges of making therapies accessible, using sickle cell disease as an example. He stated that initial sickle cell programs would rely on toxic conditioning regimens like busulfan for transplants, which he said would be suitable for some severe patients but not all, and emphasized the need to improve the technology to make treatments more patient-friendly, non-toxic, and cost-effective for broader global access. Evans also mentioned that Beam Therapeutics had licensed its technology to Verve Therapeutics for a PCSK9 gene editing therapy aimed at lowering LDL cholesterol, while Beam focused on other indications. He highlighted the competitive and fast-moving nature of the field and the ongoing work required to expand the feasibility and scalability of base editing across various diseases.

Recent appearances

  • Gene Editing: From CRISPR to Curative Medicine

    March 30, 2026 · 📺 RTW Investments LP

    What if you could fix disease by rewriting DNA? From CRISPR to next-gen gene editing, Stephanie Sirota and Beam Therapeutics CEO John Evans break down base editing, prime editing, and the path to one-time cures. PODCAST TEAM Producer & Director: Devon Leaver Editor: Dominique Guerra Production Coordinator: Ying Yu Lin Production support: Annabelle Chan Executive Editorial Advisor: Stephanie Sirota Research Consultant: Piratip Pratumsuwan Theme music: Yehezkel Raz Additional music: APM Music Featuring: John Evans, CEO and Board Member of Beam Therapeutics, moderated by Stephanie Sirota, Partn…

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  • Ep97: John Evans on Base Edited Therapeutics

    June 11, 2025 · 📺 The Long Run with Luke Timmerman

    John Evans, CEO of Beam Therapeutics, on base editing technology for therapeutics.

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  • Founder Stories: John Evans, CEO of Beam Therapeutics & The Future of Base Editing

    November 30, 2022 · 📺 Axial

    John Evans joined Beam in 2017 as CEO, bringing significant experience as a company builder, dealmaker, and drug developer in the biotechnology industry. Mr. Evans was previously an early employee and member of the leadership team at Agios Pharmaceuticals, most recently serving as Senior Vice President for Corporate Development and Portfolio Leadership. At Agios, Mr. Evans served as IDH Portfolio Executive, providing strategic and operational leadership for a portfolio of first-in-class IDH inhibitors including IDHIFA and TIBSOVO. He helped initiate and lead Agios’ landmark alliance with Celg…

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  • Can we fix damaged DNA? Beam Therapeutics CEO.

    December 19, 2021 · 📺 Daily Stack Markets

    Pounding The Table's Nat Harooni is joined by CEO of Beam Therapeutics John Evans. Sign Up for Free News Letter: https://sendfox.com/poundingthetable Make sure to check out our website: www.PoundingtheTablePodcast.com You can visit our new Merchandise shop launching soon at: www.fintwitshop.com And you can follow us on Twitter: @PoundingDaTable @Anthonyohayon, @AviNMash, @Rhemarajani9, @Reilly_Mcadams, @NatHarooni, @ProblemSniper @lukedonay DISCLAIMER: All of PTT Network trades, strategies, and news coverage are based on our own opinions and made for entertainment and educational purpos…

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  • Creating and Building Innovative Biotech Companies | Careers, Life, and Yale Thursday Show

    January 08, 2021 · 📺 Yale Alumni Association

    ... with CEO of Beam Therapeutics, John Evans '99 and CEO of Akili Interactive, Eddie Martucci, Ph.D. '09 on Thursday, December ...... distinguished panelists john evans ceo of beam therapeutics and eddie martucci ceo of keely interactive so i have been working ...

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