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Daphne Zohar

Founder and Chief Executive Officer; formerly CEO, PureTech Health, Seaport Therapeutics

Search every verified Daphne Zohar interview, podcast appearance, and on-the-record quote — each transcript cross-checked by AI and human review to confirm speaker identity. Daphne Zohar, founder and CEO of PureTech Health, discussed the company's evolution and approach to biotech entrepreneurship in a May 2021 podcast appearance. She described PureTech's origins in 2005 as a venture creation model that tested academic concepts and launched subsidiary companies, including Vidanta Biosciences and Achily Interactive. According to Zohar, PureTech has since transitioned toward a more traditional R&D biotech model focused on the "brain-immune-gut axis," particularly treatments intervening in the lymphatic system, and is now advancing therapies further in clinical development on its own. She noted that 24 therapeutic candidates have emerged from the company's engine, with two receiving FDA approval. Zohar also reflected on her approach to navigating biotech development, emphasizing the need to balance "really exciting breakthrough science" with what is actionable within near-term budget constraints. She said PureTech's model includes running experiments designed to "kill the project," whether through key pre-clinical work replicating academic findings or other tests. In a personal aside, she connected the company's naming of Karuna to the concept of relieving suffering, one of the four sublime states, and expressed hope in moments of humanity amid divisiveness.

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