Ep62: Jane Grogan
Jane Grogan, CSO of Arsenal Bio, on programmable cell therapies.
Executive Vice President, Head of Research; formerly CSO, Arsenal Bio, Biogen
Search every verified Jane Grogan interview, podcast appearance, and on-the-record quote — each transcript cross-checked by AI and human review to confirm speaker identity. Jane Grogan, Executive Vice President and Head of Research at Biogen, previously served as Chief Scientific Officer at Arsenal Bio, where she discussed the company's work on programmable cell therapies. In a February 2020 podcast appearance, she described Arsenal Bio's approach to integrating technologies such as CRISPR-based genome engineering, synthetic biology, and machine learning to develop immune cell therapies for cancer. She emphasized the potential of cell therapies to complement existing treatments, noting that while protein and small molecule therapies have successful applications, they are not curative in many cases, and that engineered cells could offer multiple therapeutic modalities in a single treatment. Grogan also discussed the challenges of designing such therapies, including identifying which cellular nodes to target and the technical limitations of gene editing, particularly regarding the size of genetic modifications. She reflected on the shift toward human immunology research, noting that advances in tools and computational methods have increased interest in studying human disease directly, whereas earlier work often relied on mouse models. She also spoke about her experience building a company from scratch as CSO, highlighting the importance of team culture, vision, and external relationships in that process.
Jane Grogan, CSO of Arsenal Bio, on programmable cell therapies.
Research & Development Strategies and Trends 2024 Panelists: Dr Andrew Plump, President of Research & Development, Takeda Dr. Jane Grogan, Executive Vice President and Head of Research, Biogen Dr. Mathai Mammen, Chairman & CEO, FogPharma Dr. Robert Plenge, EVP, Chief Research Officer, Head of Research, Bristol Myers Squibb Moderator: Dr. Martin Mackay, Co-Founder, Rallybio
• Philip SHARP (Chair), Institute Professor and Professor of Biology Emeritus, Koch Institute for Integrative Cancer Research, MIT; Nobel Laureate • Ray DESHAIES, SVP Global Research Emeritus, Amgen • Pushkal GARG, Chief Medical Officer, Alnylam • Jane GROGAN, EVP, Head of Research, Biogen • George YANCOPOULOS, Board co-Chair, co-Founder, President and Chief Scientific Officer, Regeneron
Jane Grogan, Ph.D., Executive Vice President and Head of Research at Biogen, delivers the opening remarks at the 2024 Nano-Rare Patient Colloquium in Cambridge, MA on October 30. Dr. Grogan joined Biogen in 2023, bringing nearly two decades of experience leading biotech research, including fifteen years with Genentech. Dr. Grogan most recently served as the Chief Scientific Officer at Graphite Bio and ArsenalBio, both cell and gene therapy companies. During her time at Genentech, she served in several increasingly senior roles across Immunology and Immuno-oncology, covering research strategie…
As Jane Grogan anticipates the unmet needs in patients five years from now, she’s harnessing a wave of interest in targeting B cells as a key driver of an immunology expansion at Biogen. In conversation with Editor in Chief Simone Fishburn on #TheBioCenturyShow, Grogan, who became EVP and head of research of Biogen in October, discusses how she’s approaching the mission to build diversity and balance the risk in the company’s portfolio, extending further into disease areas beyond neurology. View full story: https://www.biocentury.com/article/65... #biotech #biopharma #pharma #lifescience #Ra…
Two Scientists Walk Into a Bar is back for a third season with host Jane Grogan chatting with scientists who are leading the charge to understand complex diseases. This season will tackle a range of new topics, including a deep dive into the human microbiome, the latest in multiple sclerosis, asthma and aging, and how Big Data is redefining personalized healthcare. Subscribe today so you don’t miss an episode!
Jane Grogan and her producer Wellington Bowler are back for a second season of Two Scientists Walk Into a Bar. After a summer hiatus, Jane is eager to take on a new season of topics, including the 101 on proteins, infectious disease, how tumor microenvironments work and cell death. Subscribe today so you don’t miss an episode!
Our bodies are full of bacteria - pounds of them actually. We’re kicking off Season 3 with a closer look at the human microbiome and what happens when the synergistic relationship between our cells and our bacteria goes awry. Jane Grogan talks about the latest discoveries in microbiome research with Allyson Byrd, Associate Scientist, Cancer Immunology, Bioinformatics.
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