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David Friedberg

CEO, Ohalo Genetics; Co-host, All-In Podcast, Ohalo Genetics

Search every verified David Friedberg interview, podcast appearance, and on-the-record quote — each transcript cross-checked by AI and human review to confirm speaker identity. David Friedberg, CEO of Ohalo Genetics and co-host of the All-In Podcast, has been active across multiple episodes in late 2026, discussing topics ranging from AI and macroeconomic policy to technology adoption. On the podcast, he argued that the US faces an "unaffordability crisis," noting that 63% of Americans live paycheck to paycheck, and predicted that "socialism is coming" as a result of rising government spending and wealth inequality. He also described the US as an "empire in decline," citing debt-to-GDP ratios and slower growth compared to other nations. Friedberg commented on AI, calling it "the most important subject of our time," and expressed skepticism about doomer narratives, saying he believes open-source models will enable new billionaires to emerge from scratch, similar to the internet era. Friedberg also participated in a promotional appearance with Salesforce CEO Marc Benioff, explaining that Ohalo switched its CRM platform to Salesforce because "vibe coding" a custom solution proved unsustainable for maintenance and security. He said the company needed a "deterministic platform" for core operations and praised the speed of implementation, stating that using AI tools like Claude and Cursor allowed them to stand up the system in about 30 days, compared to months previously. In other podcast appearances, he engaged with guests including IBM CEO Arvind Krishna and Palantir CEO Nikesh Arora on quantum computing and AI cybersecurity, and interviewed Elizabeth Holmes's husband Billy Evans, where he discussed aspects of Holmes's trial and prison situation.

Recent appearances

  • AI Cyber Panic, Ken Griffin’s Bubble Warning, The Fall of France?

    October 23, 2026 · 📺 All-In Podcast

    (0:00) Bestie intros! (0:11) Ken Griffin's AI bubble warning (8:19) Palo Alto Networks CEO Nikesh Arora joins (14:24) AI Cyber panic: PHP exploits and the tumultuous year ahead (44:17) France on the brink: Riots, immigration referendum, debt crisis (1:31:49) Trump's second half strategy, Press Secretary J-Cal? Follow the besties: https://x.com/chamath https://x.com/Jason https://x.com/DavidSacks https://x.com/friedberg Follow on X: https://x.com/theallinpod Follow on Instagram:   / theallinpod   Follow on TikTok:   / allin   Follow on LinkedIn:   / allinpod   Intro Music Credit: https:…

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  • Arvind Krishna & Nikesh Arora: Quantum Threat, Open vs Frontier AI, AI Cyber Warfare & SaaS Collapse

    October 21, 2026 · 📺 All-In Podcast

    (0:00) Arvind Krishna & Nikesh Arora talk about Quantum Computing’s Threat to Encryption (9:07) Open Weight vs. Frontier AI Models (18:07) AI and Cyber Warfare (21:14) AI Regulation and the Global AI Arms Race (30:32) Vertical Integration and Software Consolidation Follow Nikesh: https://x.com/nikesharora Follow Arvind: https://x.com/ArvindKrishna Follow the besties: https://x.com/chamath https://x.com/Jason https://x.com/DavidSacks https://x.com/friedberg Follow on X: https://x.com/theallinpod Follow on Instagram:   / theallinpod   Follow on TikTok:   / allin   Follow on LinkedIn:…

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  • Elizabeth Holmes' Husband Billy Evans: The Trial, Prison & Nathan Fielder’s Documentary

    October 14, 2026 · 📺 All-In Podcast

    (0:00) Billy Evans joins Friedberg (3:38) How they met, Elizabeth the person vs the headlines, indictment (11:02) Life on trial, having a child, where she went wrong in fundraising (19:28) Understanding the verdict, sentencing, and the mistake of staying silent (26:09) Elizabeth calls from prison, her life in jail (31:34) Why they did the documentary with Nathan Fielder (35:47) The road home, restitution math, why his new company is not Theranos 2.0 Thanks to our partners for making this possible! IREN is a vertically integrated AI Cloud platform, delivering data centers, compute and softwar…

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  • Is Claude Conscious? Pope Rejects, Model Welfare Movement, OpenAI's Math Backlash, France Riots

    October 09, 2026 · 📺 All-In Podcast

    (0:00) Bestie intros! (2:53) Anthropic believes Claude might be conscious: a new religion? Lobbying the Pope, alignment risks, model welfare (38:28) OpenAI's math breakthroughs and community backlash (1:02:03) Riots in France, Friedberg's socialism metric, bond market (1:21:41) Grok Bot goes headless, OpenAI launches Dots, is IP worthless? Follow the besties: https://x.com/chamath https://x.com/Jason https://x.com/DavidSacks https://x.com/friedberg Follow on X: https://x.com/theallinpod Follow on Instagram:   / theallinpod   Follow on TikTok:   / allin   Follow on LinkedIn:   / allinpod…

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  • Trump’s Super Intelligence Summit, AI Safety Accord, GDP Beats, Midterm Predictions

    October 02, 2026 · 📺 All-In Podcast

    (0:00) Bestie intros! (2:01) Trump’s Super Intelligence Summit: Behind the scenes and how the accord was created and signed (17:57) Cybersecurity arms race, data center national security, America.gov, coordinated doomer messaging (45:22) Recent economic data: GDP, jobs, diesel, inflation, rates, manufacturing, poverty, and more (1:00:24) Midterm predictions, 2028 look ahead (1:09:28) Media coverage of attempted terrorist hijacking Follow the besties: https://x.com/chamath https://x.com/Jason https://x.com/DavidSacks https://x.com/friedberg Follow on X: https://x.com/theallinpod Follow on I…

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  • Anthropic IPO at Risk, Meta’s Muse Pop, Token Prices Fall, Open Source Gains Share, Alignment Fails

    September 25, 2026 · 📺 All-In Podcast

    (0:00) Bestie Intros: Favorite All-In Summit moments (3:54) Reacting to AI chaos: Liability, competition, and rebranding frontier "labs" (20:03) Non-frontier performance and cost: What this means for frontier companies (29:22) Anthropic and OpenAI postpone IPOs: liquidity risk and open source pressure (53:11) Political reactions to "Pacing the Frontier": Bernie's AI ban, Trump, Bessent, Obama (1:07:58) Meta launches Muse, AI "alignment," Oracle's Force Majeure (1:27:13) Anthropic’s bio research and "wet lab" in SF Follow the besties: https://x.com/chamath https://x.com/Jason https://x.com/Da…

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  • Marc Benioff & David Friedberg: Why Ohalo Switched to Salesforce

    September 01, 2026 · 📺 Salesforce

    Trying to build custom AI agents on a legacy CRM takes months of endless developer tickets. That's why Ohalo CEO Friedberg had to scrap his old software – and could only get everything stood up in ~30 days by switching to Salesforce. Watch the Salesforce FY27 Q2 Earnings: https://youtube.com/live/0ZHmkuZ1nF8?... ---------- #Salesforce #AgenticEnterprise #DigitalTransformation #AIAgents #EarningsCall #CRM #Ohalo #AITransformation #AgenticAI Subscribe to Salesforce’s YouTube Channel: http://bit.ly/SalesforceSubscribe Learn more about Salesforce: https://www.salesforce.com Twitter:   / sale…

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  • David Friedberg: The US Empire Is Declining And Socialism Is Coming Next!

    August 31, 2026 · 📺 The Diary Of A CEO

    Is the American Dream quietly dying? Scientist-entrepreneur David Friedberg reveals why the US is in imperial decline, why socialism is coming next, and how AI could save your job! David Friedberg is an entrepreneur and scientist, and co-host of the 'All-In Podcast,' one of the most popular business and technology podcasts in the world. He is the founder and CEO of The Production Board, and currently serves on President Trump's Council of Advisors on Science and Technology (PCAST). He explains: ◼Why a wave of socialism could come to America by 2028 ◼Why Social Security may have cost American…

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  • David Friedberg Explains America's Economic Crisis in 60 Minutes

    July 22, 2026 · 📺 Sourcery with Molly O'Shea

    David Friedberg takes America's 250th anniversary as a starting point to ask where does the country actually stand? And how do the bottom 50% get left behind? He argues the wealth gap is widely misunderstood, pointing to roughly $183 trillion in total US household net worth, compared to about $8 trillion held by billionaires and $4 trillion by the bottom half of Americans. His view is that the rich didn't take everything. Instead, the bottom 50% never got to own the productive assets that created the last 50 years of wealth, and.. as Friedberg puts it: "The truth is that the bottom 50% were l…

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  • Everything You Know Is About to Collapse - David Friedberg

    April 13, 2026 · 📺 Chris Williamson

    David Friedberg is an entrepreneur, investor, and podcaster. What will the future actually look like? With AI dominating the conversation, cutting through the noise matters more than ever. So what’s really coming, and what will it cost us? Expect to learn why the future if going to be epic even if the cost is high, why the future of tech and AI might be overblown, why we should care about the moon, what AI will actually do to jobs despite Anthropic’s new report, what the future of longevity will look like, why California has turned into a failed state and if David is concerned about the rise…

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  • In Conversation with David Friedberg, Cohost of All-In Podcast and Founder of Ohalo

    March 26, 2026 · 📺 Suffiyan Malik

    Friedberg is the cohost of the All-In Podcast, Founder of Ohalo and Advisor to President's Council on Science & Technology. This is a Special Episode of We The Builders from Hill & Valley Forum 2026: Conversation with David Friedberg on rise and fall of empires, the state of US economy, robots as an economic platform, what has changed since the Winning AI Race Summit featuring President Trump, reindustrialization, the end of institutional education and of course the California bankruptcy. Timestamps: 00:00 - Introduction 01:21 - Shifting landscape between Silicon Valley and DC 02:51 - A…

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  • Dave Friedberg on Optimizing Your Gut Microbiome, the Power of Fiber & the Mindset for Success

    March 19, 2026 · 📺 Jill & Jenna

    In this episode, we sit down with Dave Friedberg—co-founder of Supergut, co-host of the All-In podcast, and former CEO of The Climate Corporation—to break down the science of the gut microbiome and why fiber—specifically resistant starch—plays such a critical role in optimizing it. Friedberg explains why most common probiotics fail to create lasting change, and introduces resistant starch—a powerful prebiotic—as a more effective way to support long-term gut health. He walks us through how it works, including how beneficial gut bacteria ferment resistant starch to produce short-chain fatty aci…

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Verified interview transcripts

Notable quotes

“I think the point is if you put this and the other one together, you have a confiscatory government that represents the overwhelming amount of the economy where you have incredibly deleterious outcomes. That is the connect-the-dots, and you can't hide. This is the question for the United States: is which direction do you want to go? Do you want to go up the chart or down the chart on both charts that we looked at? Wh”

“France today is the same as the US. It's about 120% debt to GDP. France today is operating its national government spending deficit is 5.4% of GDP. The US is actually 6.2% of GDP. France is I think probably the first to go because they're only growing their economy at half a percent while the US is growing you know at 2.3%. So we're still kind of hanging on because we have some degree of economic growth that's allowi”

“One of the most remarkable things for me was when I went to visit in prison. That when you send money for commissary to her, 70% gets taken away because how much does she owe to the victims of the financial fraud? So, originally her sentence without these additional investors that she was never convicted of, that she was never proven guilty of having done anything to them, but they're arbitrarily added on. That's my ”

“I think what we're watching is probably the birth of a new religion, and it's not going to be called a religion, but it's going to follow sort of the same principles and it's going to have the same effects, which will ultimately be camps that have conflict with one another for aggregation of power. The thing about consciousness is it cannot be derived from logic and pure mathematics. Like, you can't prove consciousne”

“We've got a rate problem in the last 30 days or so, right? We've seen short-term rates on treasuries climb by 60 basis points. That's a pretty consequential climb. I think we haven't seen a short-term yield this high since going back to 2002. And so this massive increase in rates is obviously going to impact people's ability to refinance their home, buy a new car, purchase things on credit, and that's the majority of”

“I think we always assumed in the sci-fi novels that we would be in an era of having robot wars, and I think we failed to recognize that the software came first, and we are actually having the AI wars. And there's a war that I think we're in the middle of right now where there's kind of one side that wants to centralize, control, manage, regulate, whatever the term of the day might be, the technology. And there's anot”

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