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Sean Duffy

Co-Founder and Chief Executive Officer, Omada Health, Inc.

Search every verified Sean Duffy interview, podcast appearance, and on-the-record quote — each transcript cross-checked by AI and human review to confirm speaker identity. Sean Duffy, co-founder and CEO of Omada Health, discussed the company’s origins and current operations in two recent podcast appearances. In an October 2026 interview, he described Omada’s focus on managing metabolic diseases such as obesity, diabetes, hypertension, and high cholesterol, as well as musculoskeletal care, working primarily with self-insured employers and health plans. He stated that the traditional healthcare system remains constrained by fee-for-service and episodic care models, and argued that the current services landscape is failing despite advances in medicines and technology. He also mentioned Omada’s launch of a GLP-1 care track, noting that while drugs like semaglutide are powerful tools, they are not a “silver bullet.” In an August 2026 episode, Duffy recounted his path from medical school to founding Omada, including an internship at IDEO where he and colleagues interviewed patients with prediabetes and obesity who reported receiving only pamphlets and prescriptions. He said this experience led him to test prototypes in people’s homes before spinning the company out of IDEO. His former IDEO boss, David Webster, described Duffy as an unusual combination of creative and pragmatic, with a selfless motivation focused on following his fascination rather than building a personal legend.

Recent appearances

  • When Traditional Healthcare is Failing, Build Something Else - with Sean Duffy, CEO of Omada Health

    Back in 2011, Sean Duffy had a vision to change healthcare. So, he dropped out of Harvard Business School and Harvard Medical School to found this company, Omada Health, that brought healthcare to people instead of the other way around. Now valued at over $1 billion, Omada remains an innovative example of how to manage and treat chronic disease. But Sean’s not done yet. In this conversation, we talk about how we’re living in a time where we have the most innovative medicines ever created for metabolic disease. And, the most innovative technology landscape of all time. But the services landsc…

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  • The Secret to Building a Unicorn in Healthcare: Omada’s Sean Duffy + mentor David Webster

    When Sean Duffy was a medical student interning at IDEO, he came face to face with a hard truth: millions of Americans living with chronic disease weren't getting the support they needed to actually get healthier, and the healthcare system wasn't built to give it to them. In this episode, Sean tells the story of how an unlikely combination of engineering, medicine, and design thinking led him to spend a year testing and refining an idea in strangers' living rooms, before spinning Omada out of IDEO and eventually taking it public. His former boss at IDEO, David Webster, joins to share what he…

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  • This CEO Is Using Tech To Improve Healthcare & Is Bending The Curve Of Disease. Omada Health $OMDA

    Bio: Sean Duffy is the Co-founder and CEO of Omada Health, a between-visit care provider that addresses cardiometabolic conditions like diabetes, hypertension, prediabetes, and obesity, as well as musculoskeletal issues. He has dedicated his professional life to bridging technology, design, and care delivery to transform care experiences for patients. As a former MD/MBA candidate at Harvard, he also holds a BS in neuroscience from Columbia University. He has written extensively about digital health and the future of healthcare in The New England Journal of Medicine, The Wall Street Journal, F…

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  • Bending the Chronic Disease Curve with Sean Duffy

    Not many digital health companies go public. And even fewer do so with a model designed to fix what’s truly broken in U.S. healthcare: episodic, fragmented care that fails to support the behavior change required to manage chronic disease. Omada Health CEO Sean Duffy joins Claudia to discuss the company’s journey from scrappy startup to public company—and his biggest ambition for the future: bending the nation’s chronic disease curve, both in cost and in human suffering. Claudia and Sean talk about: 1. Omada’s “full stack” approach to chronic care 2. What Omada’s IPO signals for digital…

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  • Omada Health Co-Founder & CEO Sean Duffy

    In their first podcast since going public, Omada Health CEO Sean Duffy joins us to reflect on the journey to bend the curve of chronic disease. From walking away from the traditional PMPM model to staying grounded in clinical outcomes, Sean shares hard-earned lessons from over a decade of building Omada—from a startup in Rock Health’s Chinatown office to IPO.  We cover: 🔧 Killing PMPM before it killed them (and the business model shift that made Omada viable) 🎯 Designing digital experiences around actual outcomes and not just engagement 💡 What sets Digital Health 2.0 apart, and why the next…

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  • Omada Health CEO Sean Duffy on IPO debut: Today is the right moment for us

    Sean Duffy, Omada Health co-founder and CEO, joins 'Squawk Box' to discuss the origins of the company, IPO debut, impact of AI, and more.

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  • Sean Duffy: Innovating Digital Solutions for Chronic Disease

    Sean Duffy, Co-Founder & CEO, Omada Health Sean Duffy is the co-founder and CEO of Omada Health, a digital behavioral medicine company dedicated to inspiring and empowering people everywhere to live free of obesity-related chronic conditions like heart disease and type 2 diabetes. In 2017, Omada was recognized as one of Fast Company’s World's Most Innovative Companies and in 2016, the company was named a Technology Pioneer by the World Economic Forum. Sean’s past speaking engagements include the World Economic Forum annual conference, Clinton Global Initiative Health Matters Summit, the…

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  • Providing Lasting Healthcare Change: Omada Health’s Sean Duffy

    In this episode, we speak with Sean Duffy, the Co-Founder and CEO of Omada Health, a virtual-first healthcare provider that nurtures lifelong health, one day at a time. Since 2011, Sean and his team’s mission has been to inspire and enable people everywhere to live free of chronic disease. They do this by building digital health programs that are evidence-based, performance-priced, and designed to delight their users. Omada is backed by Andreessen Horowitz, Norwest Venture Partners, Fidelity, Wellington Management, and other notable investors. I am your host RJ Lumba.  We hope you enjoy the…

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  • Conquering Digital Health’s Steepest Slopes | Omada Health CEO Sean Duffy

    As a medical school-bound undergrad, Sean Duffy, co-founder and CEO of Omada Health, didn’t initially consider entrepreneurship as a career path. Today, Sean leads a virtual-first care provider for chronic conditions like diabetes, hypertension, and musculoskeletal disorders. Sean traces his journey from a "techie" upbringing to stints at Google and medical school, and how his early fascination with the potential of digital health ultimately led him to build Omada. Sean and Steve dive into: -The genesis of Omada's "digital DPP" (diabetes prevention program) model -How digital health has matur…

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  • Fireside Chat with Sean Duffy

    Bio Eats World is now Raising Health! On this first episode of Raising Health, Sean Duffy, cofounder and CEO of Omada Health, joins Vijay Pande, founding partner of Bio + Health. Sean and Vijay discuss the building and growth of Omada, from the early days to now. As the cofounder of one of the original digital health companies, Sean has unique insight into the growth of both the digital health field and the changing venture capital environment. They also talk about the future of AI, how Omada is leveraging AI, and the challenges that might arise with using a technology in a caregiving environ…

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  • Omada Health CEO Sean Duffy on Evolving Employer Pricing, Incorporating GLP-1s and Using LLMs

    Jacob and Nikhil sit down with Sean Duffy, the CEO of health tech unicorn Omada Health, to discuss how Omada is using Large Language Models and incorporating GLP-1s into its care. They also hit on how Omada has thought and evolved its employer pricing. 0:00 intro 0:45 starting Omada Health 5:22 how Omada differs from Sean’s original vision 9:07 evolving employer pricing 16:45 how the care model has changed over time 19:43 GLP-1s 27:39 how Omada has incorporated AI 36:38 Livongo-Teladoc merger 40:45 coining the term “digital therapeutics” 43:39 over-hyped/under-hyped 45:12 policy changes…

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  • A Look at the Future of Virtual Care with Omada Health CEO Sean Duffy

    Now that COVID changed so many perspectives when it came to virtual care, we’re going to spend the next couple years figuring out the details. And there are a lot of details and nuance when it comes to virtual care. One company that was a bit ahead of the curve on this is Omada Health. As a provider of healthcare services, from the beginning they started with a virtual-first approach to care. Incorporating virtual into the care they provide is just part of their DNA as a company. To learn from their experience, I sat down with Sean Duffy, Co-Founder and CEO at Omada Health, to understand…

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The summary and quote tags on this profile are produced with AI assistance from verified, first-person interview transcripts, then checked by our team to confirm the speaker's identity and the accuracy of every quote. See how we verify →