Founder Stories: Uğur Şahin & Özlem Türeci, Building BioNTech into an Iconic Biotech Company
With their work, Ugur Sahin and Özlem Türeci solved the basic mRNA-associated problem, namely the issue of low and short-lived protein production. In parallel, BioNTech colleague Katalin Karikó approached the emerging technology from another angle and found that the immunogenicity of mRNA could be mitigated effectively by modifying the nucleotide uridine. Discovery by discovery, improvement by improvement, the company’s scientific teams harnessed the power of mRNA while exploring new and exciting ways to deploy it. To date, the scientists behind BioNTech have optimized the structural compone…