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Paolo Ardoino
CTO, Bitfinex & Tether

Paolo Ardoino - Merger or Obsolescence - The Future for Humanity (Stewarding the Flame, Episode 3)

📅 Jul 24, 2026 The Trajectory with Dan Faggella 46 MIN 456 VIEWS 39 SEGMENTS · 2 SPEAKERS
Brain-computer interfaces are often discussed as futuristic gadgets. Paolo Ardoino argues they're something far more important: humanity's best chance of keeping pace with increasingly capable AI. In this installment of the Stewarding the Flame series, the Tether CEO explores why non-invasive BCI could become a practical "co-processor" for the human brain, why thought privacy must be protected through on-device AI, and why refusing to augment ourselves may be a greater risk than embracing the technology. This conversation explores what role human augmentation should play in carrying forward...

What Paolo Ardoino said

Written from the verified transcript and checked against it. Every figure links to the moment it was said.

Paolo Ardoino, CTO of Bitfinex and Tether, argued that robotics and AI together pose a huge threat to humanity, and that brain-computer interfaces (BCIs) are essential for humans to remain relevant. He predicted non-invasive BCIs will see surface-level development in the next 2-3 years, with a major unlock in 5-10 years and mass adoption in 15 years. He highlighted Tether's MediPSI models (1.7B and 4B parameters) outperforming Google's 27B Med-PaLM, and stressed the importance of local processing and anonymized public datasets for privacy. He dismissed AGI timelines as exaggerated due to IPO pressures, and argued that adoption of BCIs will be inevitable, driven by competition and the desire to avoid obsolescence. He criticized Europe for overregulation and predicted a global race where faster movers like China will force progress.

Key takeaways

  1. Ardoino believes robotics and AI paired together are a huge threat to humanity, and BCI is a tool to keep humans relevant.
  2. He predicts non-invasive BCI development will be surface-level for 2-3 years, with a major unlock in 5-10 years and mass adoption in 15 years.
  3. Tether's MediPSI models (1.7B and 4B parameters) outperform Google's 27B Med-PaLM in accuracy, enabling local edge compute for BCI applications.
  4. He insists on local data processing for BCI to protect privacy, citing quantum computing risks to cloud-stored thoughts.
  5. He expects BCI adoption to be inevitable, driven by competition and the need to compete with machines, despite regulatory slowdowns.

Numbers and commitments

FigureWhat it refers toTypeAt
1.7 billion parameters in Tether's MediPSI model metric 6:12
4 billion parameters in Tether's larger MediPSI model metric 6:12
27 billion parameters in Google's Med-PaLM model metric 6:12
1% precision of non-invasive BCI compared to invasive metric 6:12
5-10 years timeline for major BCI unlock timeline 3:25
15 years timeline for mass adoption of BCI timeline 3:25
18 months exaggerated AGI timeline he dismisses timeline 14:07
80% chance he thinks AI and robotics will go well metric 0:00
1% chance of things going wrong that is still significant metric 0:00

Chapters

  1. 0:00Threat of AI and robotics
  2. 3:25BCI development timelines
  3. 6:12Tether's MediPSI and edge compute
  4. 11:15Privacy and local data processing
  5. 17:38Adoption inevitability and competition
  6. 27:17Stewarding the flame philosophy
  7. 36:09Europe's overregulation and global race

Questions asked in this interview

8
  1. 2:44When you look forward a year or two at what might be capable BCI-wise that really isn't today and hasn't been in the last few years, what are the most significant things from your vantage point?
  2. 4:56What are some of the technical things that the audience should know about that we're really making headway on in the field?
  3. 8:42And that if we have enough people hooked into these sorts of things, it could be the banal stuff like turning on and off the lights. Okay?
  4. 12:37What do you think is going to evolve ecosystem-wise to make people feel safe jumping into this space?
  5. 22:45Do you agree with that philosophically, or do you think about it differently?
  6. 27:17Are you more or less agreeing with this philosophy here?
  7. 31:14And should we leave it untapped?
  8. 34:04What do you think it's going to take for people to shift to this worldview?
Paolo Ardoino 0:00 ↗
I think that robotics and AI paired together will be a huge threat to humanity. We may think 80% will go well. 20%, or even 1% that could go wrong, is still a lot of percentage. So I think that we should, as humans, be prepared, or thinking, or trying to accelerate on a technology that will still make us relevant. We don't want to be living in a future where, you know, the current comparison between a human and a fish will be of a robot and a human. We should want to try to maintain the species, because evolution and basically all the Darwinian part of evolution was always about, you know, the ability of species to evolve, to try to preserve themselves, to try to become stronger, to adapt to the new ecosystem. If we are dropping the towel now as humans, I think, you know, our future will be already pre-designed.
Daniel Faggella 1:07 ↗
This is Daniel Faggella. You're tuned in to The Trajectory, and this is the second episode in our series called Stewarding the Flame, where we discuss the living process — that process that creates and overcomes itself — and how through innovation and regulation we might help to encourage its flourishing, potentially eventually as far beyond us as we are beyond the sea snails, and maybe even be part of that transformation. This episode is about exactly that. We've interviewed a couple folks of Italian descent here on the show, and maybe a handful of billionaires, but no Italian billionaires. Paolo Ardoino is the CEO of Tether, the sort of stablecoin issuer there, and his firm has invested hundreds of millions into Blackrock Neurotech, which does brain-computer interface. In this particular episode, we talk about the potential necessity of brain-computer interface as a part of the next waves of evolution of intelligence, and why that may be necessary for humans, but also necessary if we want the living process to persist and not be sort of trampled by potentially some kind of unconscious AGI that is too much of a separation from the living process that we do understand, which at least at present is in the biosphere. So, there will be much to say at the end of this episode as always, but without further ado, this was a lot of fun. This one was recorded, by the way, live in Boston. I was not in the studio, so my background is a little bit different. Paolo's background is a little bit different, but it still came through great. I hope you'll enjoy it. This is Paolo Ardoino here on The Trajectory. So, Paolo, welcome to the show.
Paolo Ardoino 2:42 ↗
Thank you for having me, Dan.
Daniel Faggella 2:44 ↗
Absolutely. You know, years ago — this is called the AI and Business Podcast, but years ago, some of our earliest episodes were in BCI. BrainGate is based in Brown University, which I grew up in Rhode Island, and it's been such a fun space to follow. But the progress generally hasn't been that exciting compared to AI, but recently that's shifted, and obviously you've gotten into this space. There's some exciting things going on. I want to open with your vision and perspective, having now skin in the game in this domain. When you look forward a year or two at what might be capable BCI-wise that really isn't today and hasn't been in the last few years, what are the most significant things from your vantage point?
Paolo Ardoino 3:25 ↗
Sure. I think that with the advent of AI, I think that in the BCI field we can make important progress. So far, most of the attempts at BCI have been invasive, which I believe is still the most prominent type of approach in terms of BCI. It's the most accurate one that provides more information and insights into the brain. There are great companies that are working on it and have been working on it for the last many years, like Blackrock Neurotech, and of course you have Neuralink and many others. But also, I think in the next few years we are going to see the rise of the non-invasive BCIs. There are some attempts to try to capture, of course, in a let's say high-level way, information coming out from the brain and use that information to govern some day-to-day tools — maybe the computer, maybe the stereo, maybe a few other things. But definitely we are going to see much more development on the non-invasive BCIs. But I would say that for the next two, three years, I expect the development still to be on the surface, high-level, and not that fast. But I truly believe that the huge unlock will come five years from now up to 10 years from now, when probably with the mass adoption of this technology in 15 years from now.
Daniel Faggella 4:56 ↗
Yeah. So, and we're going to get into that whole journey, because there's a lot of things to consider. Because, Paolo, to be frank, there's a lot of people who think we'll have AGI in, you know, 18 months from now or something like that. So if the human has to catch up, you know, in a full decade, is that enough time to shake us out? But we'll get into that stuff. But anyway, it's good to understand your timelines writ large. Maybe we can talk a little bit about, you know, of course, invasive is, you know, it's high bandwidth in the most literal sense of the word. But of course there's all kinds of challenges with dealing with living tissue and with little nanowires going into neural circuits and whatnot. The brain constantly adapting to those things and kind of resisting those things. Tons of challenges going on there. Non-invasive obviously is going to be our near-term trajectory. Let me ask, you know, when it comes to the technical things that'll start to make the non-invasive more powerful, obviously you folks at Tether are now sort of working on some of this. So when you think about breakthroughs, technology applications that are starting to open this up and let people use their computer or do other non-invasive things that are kind of useful, even if it's early-stage useful, still very practical and useful. What's leading to those breakthroughs? What are some of the technical things that the audience should know about that we're really making headway on in the field?
Paolo Ardoino 6:12 ↗
Well, I think that with the information that we can extrapolate from the non-invasive BCI, we can still do very interesting things. So you have the ability nowadays, and that is, I think, one of the most important breakthroughs of Tether. We have now the ability to run very lightweight models directly on the consumer smartphone or consumer device. So recently we were able to showcase our MediPSI, that is our med-health model, the most recent one that we built. We built two versions: the 1.7 billion parameters and the 4 billion parameters one. Both of them, especially the 4 billion parameters one, is exceeding the performance and the accuracy of the 27 billion parameters Med-PaLM medical health model from Google. So with a fraction of the size, we are able to be even more accurate than the 27 billion parameters from Google. So there are so many breakthroughs on the local edge compute and LLMs that allow us to be confident that when we extrapolate even imperfect information from non-invasive BCI, we can still use that to run models and to transform that information into real actions. You know, of course, again, the level of precision is probably 1% of what you get compared to invasive BCIs, but still it's enough for certain day-to-day actions like moving things, or turning up lights or down lights, or, you know, changing the music in your stereo with your brain, right? So you can start feeling that. We can start perfecting that information. But think about it: the more we get to experiment these things in day-to-day life, the more people we try it out, the more people will also provide their brain waves to us in a very anonymous way — and not us as a company, but us as, let's say, a research group. Even universities, right? We want to see an open effort to use this information that comes out from the brain to be used to train models and open models. We really believe in open-source models that can be helpful to humanity, that can be used then also into the medical field more and more.
Daniel Faggella 8:42 ↗
Yeah. So, you know, it strikes me, Paolo, that, you know, however many tens of thousands of years ago, you know, language became more robust and popular, and people experimented with making noises and sounds, and now all of our brains are completely rewired to be vocally and symbolically communicating at all times. We swim in this parallel symbolic world. Obviously, you know, I live most of my life on a computer screen, just like you do. And, you know, my fingertips are really good at a bunch of stuff that my great-grandparents never thought their fingertips would be good at. In terms of the vast majority of my work, it strikes me that even non-invasively, there will become new habits and things we take for granted that we just do mentally — we no longer do with our hands, we no longer do with our mouths. And that if we have enough people hooked into these sorts of things, it could be the banal stuff like turning on and off the lights. Okay? It could be before I go to sleep, I want to remember something that I was going to do. And so I kick off a Slack message, you know, in my mind before I — you know, while I'm in bed, sort of before I'm going to bed, I like kick off a couple notes to myself or whatever. In some cases maybe even without having to type or do anything like that. Little habits like that might compile. And then when you look at a day in the life of an average human, even with non-invasive, you might notice many telepathic advantages in terms of speed, productivity, convenience, etc. And it seems like getting mass adoption even of that low — you said 1/100th, which is probably, I don't know how accurate, right, very, very low bandwidth — but even at that level, if we do it in bulk, it feels like that could be pretty transformative as a first step in the first place.
Paolo Ardoino 10:24 ↗
I agree, especially if you can add the concept of silent speech. So you in part use, of course, the information coming directly from the brain, plus, you know, the small movements of your mouth. Any additional information will make the systems much more precise, right? So I think, as you said, there are things that, you know, remember information, like, you know, taking notes for yourself, doing little things, you know, turning on and off stuff, and, you know, commanding things by voice mode, commanding the television, you know, even moving the cursor on your screen. These are things that could be done also with non-invasive BCI. And so what I do care about, though, is the privacy of this, because we start entering the field of the most intimate thoughts.
Daniel Faggella 11:11 ↗
Oh yeah, incredible security concerns here. Yeah.
Paolo Ardoino 11:15 ↗
Yes. So that is why we believe that having this — especially because it's low bandwidth, the information contained in those brain waves and silent speech in a certain way is limited, right? So we believe that local devices are perfect to analyze that, because they do not require super important power. But yeah, so that's where we see the biggest breakthroughs, and we still believe that we can use existing LLMs or adaptations of the existing LLMs. Like our team was able to — well, this in case partly comes from very complex stuff — but we were able to train models, adaptations of the Whisper model, for our brain-to-text challenge and model that allows basically public information taken from the human brain to be used to train new models that would use brain waves to capture what people were thinking in that specific moment in time. Right? So these things are possible. We believe that it's important to create anonymized public datasets so that researchers all over the world will be able to build the most amazing user experiences.
Daniel Faggella 12:37 ↗
Yeah. Yeah, obviously, I mean, so there's a thinker, a fellow Italian, Luciano Floridi, who says the mark of a mature civilization is that it can be brought to its knees by a cyber attack. And I think he's basically right. And one wonders, what are the new possibilities and risks of everybody looped into things that are reading their thoughts all day long, right? And feeding those thoughts into personal AIs that help them with their habits or help them with their work or whatever the case may be. Clearly new security concerns. Clearly some elements of decentralization and encryption and whatever else are going to have to be kind of evolved in parallel. Any thoughts from your vantage point? Because for that ecosystem to thrive, I suspect people will need to know that they won't be bombarded with brain-customized advertisements, or have politicians lightly bend their perspectives on almost everything they think about just enough to vote for the right kinds of things. Right? People probably won't dive in without some degree of that security. What do you think is going to evolve ecosystem-wise to make people feel safe jumping into this space?
Paolo Ardoino 13:56 ↗
Well, right there is a lot to unpack there. Well, first of all, I think — well, you described, I think, one of the episodes of Black Mirror.
Daniel Faggella 14:05 ↗
Love that episode.
Paolo Ardoino 14:07 ↗
But it's a real concern, right? So first of all, connecting to what you were saying before, you have the huge breakthrough — you used the example of your fingers. Your fingers and your voice — our voice has been, I would say, an analog system, right? So we have almost like a digital brain, we have an analog communication system that is our voice and fingers. And then basically now we have the chance to start using something like a mathematical processor in our brain. Great. But the more we start relying on it, will create a huge dependency, and that could be exposing the entire civilization to big threats. Completely agree with that, and that is very scary. That's why again we are pushing for at least allowing people to have full control over their own thoughts and their information. Sure, encryption, sure all that. But you know, I would not trust my information, my brain thoughts, to be stored on cloud. Also because if we were using — let's say that we were doing this 10 years ago, right? So imagine that even 10 years ago we had already this technology that was able to allow us to extract the thoughts from our brain and store them in cloud with a stronger cryptography. Then, you know, we already talked about quantum compute. So someone with a quantum computer could in the future break the stored information in cloud that was containing our thoughts, even if encrypted. So we need to also think about — in the context of encryption is great, but also the locality of data is fundamental, because if someone had access to that information even years later with a more powerful technology, could decrypt it. So not storing that information in cloud is very, very, very important. So we want to focus on that. But on top of that, I want to reiterate that I believe people will start using this technology in the future just as a way to communicate. So you are right, like you have AI, maybe AGI will come in the next 18 months, and maybe robots will kill all of us, and maybe nothing of this will matter. But if the timelines — I still believe that these timelines are greatly exaggerated by the fact that many of these companies are going on IPO, and so they have to say that they are going to be super transformational and they are going to be the best, and they, you know, they... But still, I believe the timelines are going to be different and will allow — and I believe truly that BCI is a tool that will create an edge for humans to remain relevant and to compete with AI. So this is the full concept of a mathematical core processor in your brain. When I was a kid, the first computer that I had was a 286, and you could get a segregated mathematical processor that you could plug in to make the computer much faster and better, at least in certain types of operations. And I believe that will be the same with BCI, right? So eventually, when people — when few people — because if you at some point, let's say, BCI will be ready for consumer time, and then you will go around the street, you stop 1,000 people, will ask them, 'Oh, would you implant something in your brain?' 999 will say, 'Are you crazy? We'll never do that.'
Daniel Faggella 17:37 ↗
Of course, of course.
Paolo Ardoino 17:38 ↗
But the guy that will do it will probably be faster in thinking, will be, you know, have an excellent job, and so on. So the next time you ask another, people will say yes, and next time we're at 10 and 15. So adoption will come.
Daniel Faggella 17:52 ↗
Yes. Yeah. So look, here's my opinion. Like, you and I live like monsters or gods compared to our great-grandparents. So like, you look at screens all day and you talk to people you've never met before on the other side of the world. You see my face moving and I see your face moving, and your whole day is this. And like, and then when you get in a car, it's often driven by somebody you don't know because you pushed an app button, and then you fly in a metal tube to other parts around the world. Like, you live like a monster or a god. People always — if you could tell your great-great-grandmother wherever she was in, you know, Trani or something, you know, like, 'Hey, you're going to have a great-great-grandson, and here's what his life is going to be like,' she would say two things. One, that's obviously just physically impossible. Two, no one would do something so unnatural and terrible. Because what we do as humans is we normalize whatever band of reality we're living in. But it seems obvious to me that you are correct. Either for pleasure or for power, the adoption of this technology would be non-optional. So if I want a relaxing experience, I want BCI to be trained on every time I was peak relaxed and to conjure for me the ideal relaxing experience. When I want to feel humor, or novelty, or courage, or what have you, I would like that emotion conjured from me by evidence of all the past peak experiences of that emotion. And anything less than that, even reading the biography of Bonaparte or whatever the case may be, will pale in comparison. And so for pleasure it will be mandatory. For power, that is to say productivity, being able to do things in the world, it will be completely mandatory. When AIs are — I mean, sleep is going to be — I think if you sleep, by the time you wake up, you don't have a job. So I think that like, we're entering a digital state of nature that's vastly more ferocious and vastly faster moving. And of course we're going to need these co-processors, and eventually it'll go farther than co-processors, which we'll talk about. But, you know, people will sort of need this kind of thing. I wonder, like, again, it sounds like from your vantage point, hopefully AGI will be transformative, but not so transformative that when this tech kind of keeps up, we'll be able to still find, let's call it, pockets of human-in-the-loop-ness where our multicontextual sort of volitional forces can still add value to the meta system in terms of the sciences, the economy, etc. This is your hope and vision right now.
Paolo Ardoino 20:24 ↗
Well, I think that there are multiple angles to that, right? So first there is a human hope, right? So trying to defend the species and hoping that it will turn out exactly in that way. There will be probably one slowdown that will prevent AGI to kill all of us, is, you know, multiple regulations that will try to slow down that process.

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APA

Ardoino, P. (2026, July 24). Paolo Ardoino - Merger or Obsolescence - The Future for Humanity (Stewarding the Flame, Episode 3) [Interview transcript]. The Trajectory with Dan Faggella. CEOInterviews.AI. https://ceointerviews.ai/interview/3027463/

MLA

Paolo Ardoino. "Paolo Ardoino - Merger or Obsolescence - The Future for Humanity (Stewarding the Flame, Episode 3)." The Trajectory with Dan Faggella, 24 Jul. 2026. Transcript, CEOInterviews.AI, https://ceointerviews.ai/interview/3027463/.

BibTeX
@misc{ardoino2026_3027463,
  author       = {Paolo Ardoino},
  title        = {Paolo Ardoino - Merger or Obsolescence - The Future for Humanity (Stewarding the Flame, Episode 3)},
  howpublished = {Interview transcript, The Trajectory with Dan Faggella. CEOInterviews.AI},
  year         = {2026},
  month        = {jul},
  url          = {https://ceointerviews.ai/interview/3027463/},
  note         = {Speaker-attributed transcript with timestamps}
}