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Joseph Chang
Executive Vice President & Chief Scientific Officer, NU SKIN ENTERPRISES -CL A

Let's Talk Prysm iO with Dr Joe Chang

📅 Jan 16, 2026 OTGSystem007 52 MIN 8 VIEWS 302 SEGMENTS · 2 SPEAKERS
In this live episode of Beneath the Label, Dr. Joe Chang (Chair, Scientific Advisory Board) explains the 20-year journey from the original BioPhotonic scanner to the new Prism device. Learn why skin carotenoids are a powerful biomarker for antioxidant and nutritional status, how Nu Skin’s Raman scanner database + AI translate scan readings into actionable nutrition insights, why Prism is more precise and consumer-friendly, and which products (like LifePak Nano) and behaviors most reliably raise your score. Practical takeaways include scanning frequency, how scores relate to blood measures, and...

Questions asked in this interview

12
  1. 0:27When you were you just came out from high school, right?
  2. 3:06And I'm sure that all of you have seen it. Hopefully, very soon, isn't it?
  3. 10:07And and they will say, 'Whoa, you know, this is this is a what?
  4. 16:53And we're putting it available to everybody, right?
  5. 18:33What's your favorite SCS product, Joe?
  6. 20:37And the and the more variety in your color and all these things, right?
  7. 29:32We haven't given away the Nano, have we?
  8. 33:53Which I love. Now, what's happening?
  9. 36:46And then I actually take the New Biome too. Do you?
  10. 37:05to competitors that they'll sell their own products?
  11. 41:58Do you need then to take these products with food? Or does that matter?
  12. 45:10Is it that I'm trying is it the aging factors that I'm looking at or is it overall general health?
Kathy Schultz 0:05 ↗
Hello everyone. I'm Kathy Schultz and with me today, I couldn't be more excited. My good friend Dr. Joe Chang. Joe. Okay. You said I couldn't do like the big introductions for you, Joe, but Joe is our chairman of the scientific advisory board. And you've been at Nu Skin 25 years at least.
Joseph Chang 0:24 ↗
At least. And we've I worked with you 25 years ago.
Kathy Schultz 0:27 ↗
Indeed. When you were you just came out from high school, right?
Joseph Chang 0:31 ↗
No, I was I was a professional when I started working with Joe. But before you came before you started Pharminx, you also worked in the pharmaceutical industry.
Indeed.
Kathy Schultz 0:40 ↗
And before that and how long were you in the pharmaceutical industry?
Joseph Chang 0:43 ↗
I think I reckon if I look back about close to 15 years.
Kathy Schultz 0:47 ↗
About 15 years.
Joseph Chang 0:47 ↗
Yeah. Yeah. Before I left and sort of actually started one company, sold that, and then started Pharminx.
Kathy Schultz 0:57 ↗
And then started Pharminx.
Joseph Chang 0:58 ↗
That's yeah that's what happened. And then we were lucky enough to combine Pharminx into the Nu Skin family.
Kathy Schultz 1:04 ↗
Right, 1998.
Joseph Chang 1:05 ↗
1998 and work together with that. And before we're just going to get a little bit of Joe and then we're going to go straight into Prism and SCS. Before that you said you were an instructor at Hopkins.
Yes, I was on the faculty at Johns Hopkins in Baltimore. Yep. That was a lot of fun teaching students and sort of doing research at Hopkins and then I got recruited out to the.
Kathy Schultz 1:27 ↗
You got recruited? So that actually answers a lot of personal questions that I think so. I Joe is a unicorn when it comes to a scientist. And I'm going to tell you guys why I think that Joe is a unicorn with this. You're so so smart, but you're able to explain it to where someone who is not a scientist can understand things. And that's got to go all the way back to when you were on faculty and teaching students is that you can take a really hard topic and make it very digestible for the average mind. And I have always loved that about you. But yeah, you can stand in a room of amazing PhD scientists and wow them with your intelligence as well. And I think that's a really unique skill that you possess. And so that's one of the reasons I'm so excited to have you here is because we're going to talk about some scientific things. Yep. And we're going to go back to your teaching days and you're going to teach us. We're going all the way back, Joe. And everyone, please feel free to put in the comments and questions as you have questions. We've gathered some questions for you already, Joe. Excited to have a live audience again on this webinar and with the Beneath the Label podcast. We have our scanner certified products here and we'll talk about what that means on this podcast and Joe, we're going to give some away. So, if you're like, you know what, that was a great question. You tell me like, hey, if this person's in the US, we're going to give we're going to send them a free product away.
Joseph Chang 2:53 ↗
Oh my goodness, that's great.
Kathy Schultz 2:55 ↗
It's going to be fun. We're going to have some fun. Okay. So, first of all, let's talk about what the Prism is.
Joseph Chang 3:01 ↗
Sure. Yeah. Absolutely. And by the way, Kathy, there's some right here.
Kathy Schultz 3:06 ↗
That's what it looks like if you haven't seen it. And I'm sure that all of you have seen it. Hopefully, very soon, isn't it? You're going to be able to use it, touch it, and use it.
Joseph Chang 3:15 ↗
Yes. That's great.
Kathy Schultz 3:16 ↗
Yes. So, it's going to We're excited because we will be getting this in the market. If people are coming to our live event, they can get it in and in October. But yes, and then even by next year, consumers can buy it. So, I want to make sure that, you know, we really get all of this out. So, we're super excited about the Prism device. Now, the Prism is not it's the first of its kind, but it has a long history. So, give us a little bit of that history.
Joseph Chang 3:40 ↗
Absolutely. I think the history here in this instance, but this with this particular device is very critical for you to totally appreciate where we are today with Prism. Okay. If you recall, we obviously have a device that we call the BioPhotonic Scanner. I believe we launched that back Oh. Oh my goodness. It's almost 20 years. It's 2003.
Kathy Schultz 4:03 ↗
2003.
Joseph Chang 4:03 ↗
Yeah. Yeah. Yeah. I think that when we first brought out the initial the original scanner, I call it we call it the S1, it was already not too bad. I mean, you got to remember, right? We when we got this technology this technology was in its infancy essentially it took up a whole room to be able to measure at that time we call them the carotenoid antioxidants and then we brought it down to this sort of toaster size thing and it was successful I mean in so far as it was able to somewhat measure antioxidants then we brought out a couple of years later the S2.
Kathy Schultz 4:46 ↗
Much smaller.
Joseph Chang 4:47 ↗
Quicker and now finally we had the the S3 which is the current device or version that's in use right now. So it's great but remember 20 years ago we all knew at that point in time the technology was measuring antioxidants in fact specifically these carotenoids. Okay, you know they're named after carrots actually that's why they're called carotenoids. Okay, that was what we can pick up and we we never sort of we sort of had a hypothesis but we never fully appreciated that it was going to mean something. Okay.
Kathy Schultz 5:29 ↗
As far as nutrition is concerned. Do all antioxidants have a like a like a skin?
Joseph Chang 5:39 ↗
No. No. The the technology that we use in the S3 is so specific only for the carotenoid antioxidants. Um, okay. Now, this is not I mean I think this is scientific, but if you feed a baby carrots and sweet potatoes, they have a visible.
Kathy Schultz 5:58 ↗
Yes.
Joseph Chang 6:00 ↗
They turn orangeish, right?
Kathy Schultz 6:01 ↗
Orange. Absolutely.
Joseph Chang 6:02 ↗
So, we know that carotenoids.
Kathy Schultz 6:04 ↗
You got it.
Joseph Chang 6:04 ↗
Can be can be measured and and seen, right?
Kathy Schultz 6:08 ↗
It can be measured in the skin more accurately.
Joseph Chang 6:12 ↗
Yes. Okay. Okay. Yes. So, we know that. But if you feed a baby too many blueberries, you don't see that same impact in the skin. Right. So that's why carotenoids are such an important one is because we know it can be measured in the skin.
Kathy Schultz 6:28 ↗
But not all can be correct.
Joseph Chang 6:29 ↗
Absolutely. But however, this is another key observation if you will, right? Which led us to a conclusion and to a broader claim and that is the carotenoid is actually a sort of sits in the center of what we call the antioxidant network in the body.
Kathy Schultz 6:49 ↗
Okay, tell me what that means.
Joseph Chang 6:50 ↗
It's not okay. It's not the only important antioxidant in the body.
Kathy Schultz 6:55 ↗
Right. Right.
Joseph Chang 6:55 ↗
The blueberries that you mentioned, they're equally important. They're good for health and so on. And there are few you know at least a few hundred others too from other plants and and fruits and so on. But essentially the carotenoid looks as if that is like a thread that sticks out from a fabric and if it's not strong and robust the whole fabric unravels.
Kathy Schultz 7:19 ↗
Really.
Joseph Chang 7:19 ↗
Yes. That's what we critical one.
Kathy Schultz 7:21 ↗
Absolutely. That's right. Over the years we we beginning to understand and appreciate that is actually a overall biomarker of antioxidants.
Joseph Chang 7:33 ↗
So not only can it be measured in the skin, correct? But it is a biomarker it's an essential biomarker that tells all of your antioxidant health.
Kathy Schultz 7:41 ↗
Right. Absolutely. It's interesting. Okay. Keep that in mind because it's going to be pretty critical historical fact that we have at least on the hypothesis.
Joseph Chang 7:51 ↗
Okay. Look upon it like cholesterol. When you think about it, why do we all worry about cholesterol and we take, you know, on from the pharmaceutical side and this is coming out from my pharmaceutical background, right? That is because they had over 20 years worth of data to suggest that cholesterol can eventually increase your risk of other things because it's a key marker.
Kathy Schultz 8:12 ↗
It's a key marker.
Joseph Chang 8:13 ↗
So these key biomarkers absolutely are so important. That's what we mean.
Kathy Schultz 8:17 ↗
Interesting. Yeah. So, but it's a key marker to other things and carotenoids are a key marker to health and nutritional status. Okay, that's the you got to keep that in mind because that's where we're going to go.
Joseph Chang 8:30 ↗
I feel like I probably should have known that.
Kathy Schultz 8:34 ↗
I hope it's clear, right? Those are the two dots that we'll be connecting today.
Joseph Chang 8:37 ↗
Okay, I love that. And and so that's why we think it's so important to have a device that can measure your carotenoid score.
Kathy Schultz 8:47 ↗
That's right. And because it's it's an important biomarker.
Joseph Chang 8:51 ↗
Up to that point, up to couple of years ago, all right, we were not able to make that connection to call it a biomarker. Okay. And here's why. Over the last 20 years, okay, we gathered a lot of data. And what you may or may not know Kathy is the fact that while we are getting the overall score if you were to we call it a scanner score right or the skin carotenoid score 10,000 50,000 whatever we actually have some lifestyle sort of elements that we collected to data.
Kathy Schultz 9:28 ↗
Right okay so we're like what's your your BMI.
Joseph Chang 9:32 ↗
Your BMI okay.
Kathy Schultz 9:33 ↗
Do you smoke.
Joseph Chang 9:34 ↗
Y.
Kathy Schultz 9:34 ↗
What's your diet.
Joseph Chang 9:35 ↗
No I don't smoke things like that Right. I answered the question the you know your diet what do you eat?
Kathy Schultz 9:44 ↗
Where do you live right with pollution?
Joseph Chang 9:46 ↗
Pollution environment you know and and stuff like that. So we got a lot of that data. Okay. So that is what we now know or what we now call the scanner database.
Kathy Schultz 10:01 ↗
So we've gathered all of that in addition to those scores.
Joseph Chang 10:05 ↗
Raman database. Okay.
Kathy Schultz 10:07 ↗
You've heard a lot of folks going out when they talk about the Prism, right? And and they will say, 'Whoa, you know, this is this is a what? Truly intelligent wellness device.' I think we've been using that slogan quite a bit.
Joseph Chang 10:21 ↗
Yeah.
Kathy Schultz 10:22 ↗
How did it become intelligent?
Joseph Chang 10:25 ↗
Right. Yeah. It cannot become intelligent if we did not have or we do not have that Raman scanner database of information because the number by itself doesn't give you enough information.
Kathy Schultz 10:39 ↗
Artificial intelligence doesn't work if you don't have data.
Joseph Chang 10:44 ↗
Right. Right. And if you have too much data.
Kathy Schultz 10:47 ↗
Yeah.
Joseph Chang 10:48 ↗
You and I can't process it. And so you need AI to do that. Right. Think about it here. Here's the another thing that that perhaps you can now appreciate why I'm sort of really excited because we are unique. We have this data back. When you were born, you had a brain, right? I had a brain. You had a brain.
Kathy Schultz 11:05 ↗
We should be have been instantly clever or intelligent. How come?
Joseph Chang 11:10 ↗
We're not.
Kathy Schultz 11:11 ↗
No.
Joseph Chang 11:11 ↗
What happened? Our parents sent us to school and we eventually go off to college. Whatever it is. What do you think we were doing in school? We were putting data into our brain. That's how we became intelligent. Even a human cannot become intelligent without data, right?
Kathy Schultz 11:31 ↗
Yeah.
Joseph Chang 11:32 ↗
So, how would you expect a computer, this AI as we call it, how how would you expect that to work if you don't have data?
Kathy Schultz 11:41 ↗
There's no data. So, it's the 20 years of data.
Joseph Chang 11:44 ↗
That is critical.
Kathy Schultz 11:45 ↗
It's critical.
Joseph Chang 11:46 ↗
It's critical. And we weren't only gathering scan scores. And that is also critical is all these pieces together and we correlate what happen what if you get a certain value on a scanner how does that correlate to your lifestyle.
Kathy Schultz 12:04 ↗
To your lifestyle and and overall health right.
Joseph Chang 12:08 ↗
And then therefore if we look at it we now know for example you know there is I I shouldn't say well I would use we have an inverse correlation in other words when a score is down. All things being equal in a person between two people. All right. Except that one has a score lower than the other. That person is not eating well. Could be one causative factor.
Kathy Schultz 12:34 ↗
Yeah.
Joseph Chang 12:34 ↗
Okay. Or that person smokes. These these things we know are not good for establishing an optimal nutritional status in the body. It's it cannot happen. Yeah.
Kathy Schultz 12:49 ↗
So, we got those correlation, you know.
Joseph Chang 12:52 ↗
Yeah.
Kathy Schultz 12:52 ↗
It's like ChatGPT.
Joseph Chang 12:54 ↗
All that data together.
Kathy Schultz 12:55 ↗
Uhhuh.
Joseph Chang 12:56 ↗
Okay.
Kathy Schultz 12:56 ↗
And we put it in and we can give you Now, while we're talking about scores, we've gotten some questions on scoring.
Joseph Chang 13:04 ↗
So, now the S3 today's goes up to 100,000.
Kathy Schultz 13:09 ↗
100. Yeah. That's the scale.
Joseph Chang 13:11 ↗
That's the scale. But it's still the red to purple. It's still the same rainbow color. Same color scale. And the Prism we've taken it down to a thousand instead of a hundred thousand 10,000.
Kathy Schultz 13:26 ↗
It's going to be about I think right now as we are planning it it's going to be about 0 to 500.
Joseph Chang 13:32 ↗
0 to 1500 okay.
Kathy Schultz 13:34 ↗
Now let's talk about why the scoring system is different and what does that what does it what does it do is it an arbitrary number.
Joseph Chang 13:43 ↗
It is an arbitrary unit in other words it doesn't have milligrams associated with it. It's just it doesn't have you know cc's of carotenoid associated with it. All of us are sort of used to seeing something but the reason why we didn't put it is because we want to have a scale that is antioxidant related and we don't want and we can actually convert that to carotenoids.
Kathy Schultz 14:10 ↗
Okay.
Joseph Chang 14:10 ↗
From with a equation that we have.
Kathy Schultz 14:13 ↗
Okay.
Joseph Chang 14:13 ↗
All right. It's so it's connected. It means something. In other words, just because it's arbitrary.
Kathy Schultz 14:18 ↗
Doesn't mean.
Joseph Chang 14:19 ↗
It doesn't mean it doesn't mean it doesn't mean anything.
Kathy Schultz 14:21 ↗
It's arbitrary units but it's not an arbitrary number.
Joseph Chang 14:24 ↗
Correct.
Kathy Schultz 14:25 ↗
Okay.
Joseph Chang 14:25 ↗
All right.
Kathy Schultz 14:25 ↗
Okay.
Joseph Chang 14:26 ↗
So, and therefore you should look upon it 60,000 is better antioxidant protection based on the current scan the the S3 relative to let's say 30,000. That's clear, right? And here I'll explain to it. Yes, we are measuring antioxidants carotenoid as we have been talking about the last few minutes, right?
Kathy Schultz 14:49 ↗
Utilizing the AI database.
Joseph Chang 14:51 ↗
Correct.
Kathy Schultz 14:52 ↗
And so that's why this scale is different.
Joseph Chang 14:55 ↗
It has to be different than the S3.
Kathy Schultz 14:57 ↗
Yeah. If we use the same scale, it you would have a bit more difficulty seeing that transformation.
Joseph Chang 15:05 ↗
Okay. Okay.
Kathy Schultz 15:08 ↗
You know.
Joseph Chang 15:08 ↗
Yeah. So that's because we're using all this data.
Kathy Schultz 15:11 ↗
We're using all this data. It's unique. Nobody has it.
Joseph Chang 15:14 ↗
This 25 years worth of data.
Kathy Schultz 15:16 ↗
It's our data.
Joseph Chang 15:17 ↗
The scanner database is part and parcel of ours of our technology, you know. So it's it's it's maybe I can give you another analogy and you can look at this and and and maybe you can sort of look at this with this backdrop. When you when all of us look at a pyramids, right, immediately we sort of start looking at walls and so on and we starting to see little figures being drawn on it, right?
Kathy Schultz 15:44 ↗
Yeah.
Joseph Chang 15:45 ↗
We sort of collectively those figures are known as hieroglyphics. More than 100 slightly 160 years ago, nobody in the world knew that it was a language.
Kathy Schultz 15:56 ↗
They just looked like they look like cartoons, right? Nobody knew.
Joseph Chang 16:01 ↗
It was until the discovery actually Napoleon while he captured Egypt he actually recovered a slab of stone that is now known as the Rosetta stone and as hieroglyphics ancient Greek and modern Greek and they were all talking about the same thing and that's when scholars were able to translate and be able to appreciate that hieroglyphics.
Kathy Schultz 16:29 ↗
Is the language.
Joseph Chang 16:30 ↗
And they were able to then understand how the Egyptians were living 5,000 years ago. The antioxidant is sort of like a hieroglyphics in nutritional health here.
Kathy Schultz 16:45 ↗
But now with this database that we have, we have been able to translate that to mean something.
Joseph Chang 16:52 ↗
I love that.
Kathy Schultz 16:53 ↗
And that's nutritional health. And we're putting it available to everybody, right? Like we now I mean you you have it here.
Joseph Chang 17:02 ↗
We now have it, right? Which is which is amazing. That we have that. Okay. We have a let's see if I can we have a couple questions kind of leading on to what you're talking about. Now now the questions are coming in and we explained that because the carotenoid is a biomarker.
Kathy Schultz 17:18 ↗
Correct.
Joseph Chang 17:19 ↗
To all of your antioxidants and in addition we're also using this score with the carotenoid and all of the lifestyle database.
Kathy Schultz 17:28 ↗
Yes.
Joseph Chang 17:28 ↗
So that's why it's more than just a carotenoid score is because of the database of information correlated to the carotenoid score. Did I explain that right?
Kathy Schultz 17:39 ↗
Did I understand it? Okay. I'm trying to redo it to make sure that I understand it too. Okay.
Joseph Chang 17:44 ↗
Yeah. If if we don't have the database, okay, we would never know we would never know that this carotenoid is a biomarker, right?
Kathy Schultz 17:52 ↗
It's connected, right? Okay.
Joseph Chang 17:54 ↗
You know, to to the rest of all the other things.
Kathy Schultz 17:56 ↗
And another question in here is now how do we increase a score?
Joseph Chang 18:04 ↗
Okay, how do you that's is it's sort of like that's that's a sneaky question. Actually, it's not a bad question. All right. You You need to give a prize to whoever asked that question. Let's see. Okay. Wait. Let's see. By the way, it's only for us. If the question came from a US.
Kathy Schultz 18:20 ↗
Okay. So, Kimberly, if you will please. So, I asked your question in slightly different words. If you will please follow the Made by Nu Skin account and message us that you have now won. What should we give her?
Joseph Chang 18:31 ↗
I don't know. What do we give her?
Kathy Schultz 18:33 ↗
What's your favorite SCS product, Joe?
Joseph Chang 18:35 ↗
Oh.
Kathy Schultz 18:35 ↗
Oh, I'm not going to make you pick a favorite.
Joseph Chang 18:37 ↗
No, I'm not going to make me. But since I have my hands on Youth Age Lock Youth for Kimberly. So make sure you follow us on Made by Nu Skin and and do that. And now let's talk about okay.

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APA, MLA, BibTeX
APA

Chang, J. (2026, January 16). Let's Talk Prysm iO with Dr Joe Chang [Interview transcript]. OTGSystem007. CEOInterviews.AI. https://ceointerviews.ai/interview/653374/

MLA

Joseph Chang. "Let's Talk Prysm iO with Dr Joe Chang." OTGSystem007, 16 Jan. 2026. Transcript, CEOInterviews.AI, https://ceointerviews.ai/interview/653374/.

BibTeX
@misc{chang2026_653374,
  author       = {Joseph Chang},
  title        = {Let's Talk Prysm iO with Dr  Joe Chang},
  howpublished = {Interview transcript, OTGSystem007. CEOInterviews.AI},
  year         = {2026},
  month        = {jan},
  url          = {https://ceointerviews.ai/interview/653374/},
  note         = {Speaker-attributed transcript with timestamps}
}