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Joseph Chang

Executive Vice President & Chief Scientific Officer, Nu Skin Enterprises -cl A

Search every verified Joseph Chang interview, podcast appearance, and on-the-record quote — each transcript cross-checked by AI and human review to confirm speaker identity. Joseph Chang, Executive Vice President and Chief Scientific Officer at Nu Skin Enterprises, appeared at a Healthcare Forum on September 24, 2026, to discuss the company's PRYSM product and its approach to biological aging. During the presentation, he described PRYSM as a tool that can provide an aging-related score in 15 seconds, claiming that a high score correlates with a body being about four years younger than chronological age. He framed the product as part of a broader "aging franchise" and encouraged healthcare professionals to use it with patients, suggesting that different types of practitioners might emphasize different benefits. Chang also offered critical commentary on existing genetic testing, stating that tests like 23andMe provide information that is essentially a "death sentence" with no actionable solution. He contrasted this with PRYSM, which he said addresses epigenetic changes influenced by environment and lifestyle. He characterized the development of PRYSM as a significant scientific achievement, calling it "the greatest discovery in my opinion in the science of aging," and noted that the project had been incubated for some time before recent studies made it viable.

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Notable quotes

“The genetic tests like 23andMe and all those profiling that they do is actually telling you what your death sentence is. There's nothing you can do. It's a problem without a solution. If there are physicians sitting here, you may realize, you know, 30 years ago when HIV was first discovered, the first thing to do is what? We went and looked for a diagnostic test. We need to have a quick test that can tell people whet”

“This is the greatest discovery in my opinion in the science of aging because it encompasses all the things that we thought were in its independent way the singular root cause of aging. No, it's never been that. The body is way more sophisticated and more complex than that. But because we know we couldn't look at all these mechanisms at the same time, we took the path of least resistance and you just go with one. It d”

“We're going to produce an entirely new class of products, which we are going to call the age and response modulators. And it comes down to ARMs. This is an entirely new class of product. The world has never seen them. And we're going to launch the first one very soon. Probably by the end of this year.”

“In January of that 1999 yeah 98 99 that one month when we recall all the products we don't sell anymore okay of the far products that month in the new skin channel the revenue just from Farmanx products, not from Newkin products. Here's the Farmanx products. That revenue, that month's revenue was larger, greater than the prior 12 months total. That was my Yeah, you quite blame. He's the one, right? Because for sort o”

“If we had gone with my previous drug company, if we had sold to them, the business model would not have changed for intents and purposes. We would still be in the 28,000 store and perhaps with a larger budget, we could have been even double the number of stores we're going to be in. Yeah. But the marketing, the advertising that that activity is not going to change. It's going to be same except it's going to be expand”

“Drug companies don't wish to spend and commit investment working on an ingredient that they can't patent that it's natural. Those no commercial value. And I say that's rather stupid because that natural ingredient actually constantly proves itself to be far safer than the eventual drug.”

Other executives at Nu Skin Enterprises -cl A

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