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Jack Clark
Cofounder, Anthropic

Anthropic research warns AI could build itself by 2028

📅 May 07, 2026 Axios 25 MIN 8447 VIEWS 42 SEGMENTS · 2 SPEAKERS
In this exclusive interview, Axios co-founder Mike Allen sits down with Anthropic co-founder Jack Clark to discuss his warning that by 2028, AI systems may be able to improve and build better versions of themselves. Clark explains why Anthropic is preparing for the possibility of an “intelligence explosion,” how advanced AI could accelerate breakthroughs in science and medicine, and why governments, companies and researchers need new plans for cyber threats, bio risks, economic disruption and the future of work. Timestamps: 00:00 - Introduction: the future of AI 00:41 - The 2028 prediction:...

What Jack Clark said

Written from the verified transcript and checked against it. Every figure links to the moment it was said.

Jack Clark, cofounder of Anthropic, predicted that by the end of 2028, it is more likely than not that an AI system could autonomously improve itself, based on public evidence of AI's growing role in coding, science, and engineering. He described this as a new concept where technology generates its own improvement ideas, unlike past tools. Clark discussed the Anthropic Institute's focus on preparing for an 'intelligence explosion' and its 'fire drill' scenarios, including the Mythos cyber initiative and Glass Wing, which aim to make the world 'defense dominant.' He acknowledged potential job disruption and advocated for early warning signals and government partnerships, citing research on AI exposure in customer service versus biology and law. He also mentioned addressing sycophancy in Claude, the need for calibrated trust before granting AI autonomy, and plans to release primary data and improve the Anthropic Economic Index. He confirmed a compute partnership with xAI and introduced the 'jagged frontier' concept.

Key takeaways

  1. By end of 2028, more likely than not an AI system can autonomously build a better version of itself.
  2. Anthropic's Mythos cyber initiative and Glass Wing aim to create a defense-dominant cyber environment with partners including the US government.
  3. Anthropic Institute will release primary data from AI usage research and improve the Anthropic Economic Index for outside economists.
  4. Anthropic has a compute partnership with xAI, Elon Musk's lab.

Numbers and commitments

FigureWhat it refers toTypeAt
2028 Year by which AI could build itself timeline 0:49

Chapters

  1. 0:00AI self-improvement prediction
  2. 5:20Intelligence explosion and abundance
  3. 6:59Mythos and defense dominance
  4. 10:10Economic disruption and early warning
  5. 12:31Career advice in AI era
  6. 15:20Cold War analogy and geopolitics
  7. 16:46Sycophancy in the wild
  8. 18:21Trust and AI autonomy
  9. 19:18Data transparency and Economic Index
  10. 21:21Government partnership and job exposure

Questions asked in this interview

11
  1. 2:57Or help us understand how this is a leap beyond what the companies have been seeing and pushing for?
  2. 4:12So as we try to wrap our heads around this, what would this mean for Anthropic as a company? Do we need you?
  3. 6:55What do you mean by defense dominant?
  4. 7:40What have you learned now that it's in its controlled public environment?
  5. 9:30Have you had any scares with Mythos in the semi-wild?
  6. 10:10You think it's going to be a snore?
  7. 12:31What advice do you give people who ask you that?
  8. 16:29What would an example of that?
  9. 18:05Could you just walk us through that?
  10. 19:18And that would set you apart from your competitors?
  11. 20:56Or would you have to bring in your competitors?
Mike Allen 0:00 ↗
We're talking the future of AI with Jack Clark, co-founder of Anthropic. We had a chance to do this at the last second. So I'm in Miami on my laptop. Jack is in a much fancier setting, Anthropic HQ in San Francisco. Jack, welcome to Axios.
Jack Clark 0:15 ↗
Thanks for having me on, Mike.
Mike Allen 0:20 ↗
So you ignited online conversation by bringing a topic that is often whispered about, but hadn't been talked about this formally. And that is the early signs of AI contributing to speeding up research and development of the AI itself. And you're saying that by 2028, AI could be building itself. Take us to that frontier.
Jack Clark 0:49 ↗
My prediction is by the end of 2028, it's more likely than not that we have an AI system where you would be able to say to it, make a better version of yourself, and it just goes off and does that completely autonomously. And the reason for that prediction is looking carefully at many public sources of information about AI development, and seeing that we've gone from just AI systems that can do basic coding to AI systems that are now involved in the production of science itself, and also the unglamorous but fundamental engineering work involved in doing any form of large-scale R&D project. And so I decided to write a post because the purpose of Anthropic Institute is to give people a sense of what's coming, and to also start talking about concepts early, to give us time to think about them. And I think you and I would agree that an AI system that can build itself has big implications, and we'd like to start thinking about it now.
Mike Allen 1:49 ↗
And Jack, you have some trepidation about this.
Jack Clark 1:53 ↗
Maybe this is the Englishman in me, but I've had quite a lot of change in the last ten years working in the technology industry. And this is going to create even more rapid change. I think if you talk to many Americans, there is rightfully some level of trepidation about the impact of AI and the speed with which the industry is moving. And what I'm looking at is a technological trend where, if anything, the speed will accelerate further.
Mike Allen 2:24 ↗
And what you're envisioning here is AI building entire systems to replace human-built ones.
Jack Clark 2:32 ↗
Yes. Although it's a bit... I don't think that humans are not going to have anything to do. In fact, we're going to have a huge amount of work involved in validating what the AI systems have done and looking at how these new systems work. But it means that the way that AI development works will change fundamentally and the speed with which the industry moves forward will go through another ratchet and move forward even faster.
Mike Allen 2:57 ↗
And we've talked about recursive self-improvement, but is this recursive construction? Or help us understand how this is a leap beyond what the companies have been seeing and pushing for?
Jack Clark 3:11 ↗
Let's use a metaphor. Today, it's like if all of the AI companies are 3D printer companies, we have tremendously talented people working to figure out how to make the next print head on the 3D printer that can do even finer-grained things. And to do that, we need to do a lot of scientific research to improve the resolution of that printhead. The analogy here for AI is what happens if a 3D printer could suddenly make a better version of itself? What happens if a 3D printer could print that finer resolution printhead for itself and start building better versions? Now, we haven't encountered a technology like that before. It's always been the case that humans outside the technology need to come up with the ideas that then get put back into it. What happens if we have a technology that can generate ideas within itself for how to improve itself? That's a new concept. It's a new thing for us to contend with.
Mike Allen 4:12 ↗
So as we try to wrap our heads around this, what would this mean for Anthropic as a company? Do we need you?
Jack Clark 4:23 ↗
We and the other companies are going to be taking this technology and trying to get it to do good in the world, right? To help push forward things like biology or medicine or robotics. And the implication of a technology that has got a lot smarter and is able to, to some extent, adapt itself to get better, is that it's going to open up the opportunities for us as people to steer that technology into domains where it's really, really, really hard to make progress because we need incredibly talented human scientists, of which we have too few. But being able to bring a technology in to say something like cancer research and have it work much like an incredibly smart human colleague, to orient itself around that tremendously difficult topic and figure out how it would need to improve itself to get better at that task, will yield amazing things for all of us. So I think we'll be quite busy if we achieve this technology.
Mike Allen 5:20 ↗
So Jack, in your research agenda, you talk about fire drill scenarios. And there's a term, intelligence explosion, that had kind of been a theoretical term in AI safety circles. You're putting it in writing front and center. Tell us what an intelligence explosion is and why you're getting ready for it.
Jack Clark 5:41 ↗
An intelligence explosion is where suddenly the AI systems start improving very, very rapidly. And the world has a new both opportunity and problem to contend with, which is what do you do with a tremendous amount of growth or a tremendous amount of abundance in many, many different fields of science all at once. Now you want to obviously deal with some of the potential risks of that work on things like the cyber implications or for biological weapon implications. But you actually also need to have a plan for what to do with the abundance side of it, you know, what do you do to ensure that these amazing technologies flow through to benefits to people in terms of improved healthcare services, lowering the costs of making healthy food for people, generally improving things that we would all want in our world. And it's like dealing with all of today's institutions have very, very narrow pipes through which you push new drug candidates or new ideas before they come to market. How do you massively broaden the size of those pipes in advance of this abundance? And how do you work on making the world defense dominant for the potential risks the technology creates?
Mike Allen 6:55 ↗
What do you mean by defense dominant?
Jack Clark 6:59 ↗
Right now, an experiment that we are doing in close partnership with others is something called Mythos, where we have a model and we have an initiative called Glass Wing, where we are trying to equip some of the world's most significant companies and organizations and the US government with the means to make a defense-dominant cyber environment using systems that have got far, far better at understanding the cyber domain. How are you going to do that for other domains as well? That's a muscle we're going to need to build, and it will allow us to make a world that's more resilient to the kind of changes that we expect to arrive, and better prepared for them as well.
Mike Allen 7:40 ↗
Jack, I can tell you my conversations behind the scenes with the Pentagon and the administration, Mythos and its power is the reason that the Pentagon is anxious to make up with Anthropic. Why the administration is anxious to make your tools available more widely. What have you learned about the power of Mythos since you've started letting some partners use it? You knew in your lab that it had cyber penetration capabilities that were awesome, fearsome, which was the reason that you wanted to be so careful with letting it out. What have you learned now that it's in its controlled public environment?
Jack Clark 8:24 ↗
And this is the philosophy behind forming the Anthropic Institute: we have this information that only labs know about a technology like the cyber capabilities of Mythos. How do you get that to the world so that you equip the world to make better decisions? And what we've learned is that we cannot solely centralize these technologies inside a very small number of players. We have to get better at figuring out what is the community across policymakers, companies and other organizations that we can flow new technologies to so they can work on the problem together. And I think one of the most joyful things about all of this has been we've got this serious technology, we've deployed it to a set of people. And through experiencing the power of the technology they've made their organizations safer, but they've also become conscious that this isn't a one-time thing. This is the shape of the future, and it's got us to a much more, I would say, collaborative place in working the policy problem that AI presents and also coming up with solutions together.
Mike Allen 9:30 ↗
Have you had any scares with Mythos in the semi-wild?
Jack Clark 9:36 ↗
Not yet, but we are continuing to treat it as a handle-with-care technology. But ultimately the goal here is you don't want to end up in a regime where all AI technologies need to be handled with care. That would lead to issues for how you diffuse them to maximally benefit society. A lot of what we're learning is how do we build robust safeguards and robust interventions so that in the future, the whole world can have confidence in diffusing this sort of technology more widely to a broader set of people to capture more of the benefits.
Mike Allen 10:10 ↗
Now, Jack, I can't tell you how surprising are some of the elements of this research agenda. You think research agenda? You think it's going to be a snore? I was lit up by several of the points here, including you were talking about abundance for some, but there's another road where there could be real disruption, economic job pain. And one thing the institute is going to do is look for early warning signals of significant change disruption, and is going to encourage the government to help you respond to it. That is new, that is industrial policy. Tell us how you came to that, Jack.

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Cite this transcript

APA, MLA, BibTeX
APA

Clark, J. (2026, May 7). Anthropic research warns AI could build itself by 2028 [Interview transcript]. Axios. CEOInterviews.AI. https://ceointerviews.ai/interview/891077/

MLA

Jack Clark. "Anthropic research warns AI could build itself by 2028." Axios, 7 May. 2026. Transcript, CEOInterviews.AI, https://ceointerviews.ai/interview/891077/.

BibTeX
@misc{clark2026_891077,
  author       = {Jack Clark},
  title        = {Anthropic research warns AI could build itself by 2028},
  howpublished = {Interview transcript, Axios. CEOInterviews.AI},
  year         = {2026},
  month        = {may},
  url          = {https://ceointerviews.ai/interview/891077/},
  note         = {Speaker-attributed transcript with timestamps}
}