Zach Weinberg

Co-founder of Flatiron, Flatiron Health

Search every verified Zach Weinberg interview, podcast appearance, and on-the-record quote — each transcript cross-checked by AI and human review to confirm speaker identity. Zach Weinberg, co-founder of Flatiron Health and Curie.Bio, has been discussing his approach to biotech venture funding and the challenges of building companies in healthcare. In a July 2025 podcast, Weinberg and his Curie.Bio co-founder Alexis Borisy described their firm's model, which combines a $520 million venture fund with in-house drug-discovery expertise. Weinberg stated that the goal is to "free the founders" by allowing them to retain a greater percentage of ownership and control compared to traditional venture capital structures. He has also commented on the difficulty of starting therapeutics companies, saying that "being a therapeutics founder was way harder than being a software founder" due to the high cost of mistakes. Weinberg has also reflected on his earlier entrepreneurial experiences, including building Flatiron Health, which he said used a "network business" model of selling discounted software to cancer centers to aggregate clinical data. He has offered advice to founders entering healthcare without prior experience, recommending that they "embrace the current structure" and take time to understand industry regulations. In discussions about broader industry trends, Weinberg expressed skepticism about blockchain in healthcare, stating that data-sharing problems are "mostly about incentives and culture, not a technology fix," and questioned whether the current AI boom might be viewed as a "great distraction" in retrospect.