President of Quantitative Systems Pharmacology, Simulations Plus
Search every verified Steven Chang interview, podcast appearance, and on-the-record quote — each transcript cross-checked by AI and human review to confirm speaker identity. In a 2009 interview for Stanford Medical Minutes, Steven D. Chang, MD, then a professor of neurosurgery and co-director of the Stanford CyberKnife program, discussed the treatment of brain tumors and cerebrovascular conditions. He described advances such as image-guided navigation and electrophysiologic monitoring, and explained the CyberKnife as a frameless, outpatient radiosurgery system that delivers highly focused radiation in a single session. Chang noted that treatment decisions for benign brain tumors depend on factors like size, symptoms, and patient age, with large tumors often requiring conventional microsurgery and smaller ones suitable for radiosurgery. Chang also addressed malignant gliomas, stating they are managed with a multimodality approach combining surgery, radiation, and chemotherapy. He discussed arteriovenous malformations (AVMs) as abnormal blood vessels at risk of hemorrhage, with treatment options including surgery, radiosurgery, and embolization. For aneurysms, he described surgical clipping and endovascular coiling as available options, and for trigeminal neuralgia, he noted that medications often fail, leading to surgical interventions such as microsurgery or CyberKnife radiosurgery.
“Image-guided navigation is like a GPS satellite for your brain. It helps the neurosurgeon who's operating on your tumor know precisely where to make the opening into the bone and really helps guide us through the brain tissue to get to the tumor.”
“What I think you're alluding to is what's called electrophysiologic monitoring, a technique we do in conjunction with the neurology specialist at Stanford in which electrodes are placed to allow us to monitor the electrical activity of the brain during the surgery. It gives us real time feedback in terms of how the neu...”
“The CyberKnife is a machine to deliver a very highly focused beam of radiation to a tumor—unlike conventional radiation which is a wide field and exposes a lot of normal tissue, the CyberKnife is pinpoint accuracy, like a laser beam to zap a target within the brain.”
“The CyberKnife is an outpatient non-invasive treatment that doesn't require downtime or hospitalization and, unlike conventional radiation that can take weeks, the CyberKnife can often be done in a single session of 30 to 60 minutes.”
An interview with Steven D. Chang, MD, Co-Director, Stanford Cyberknife Program, providing detailed information about ...
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