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Scott Guthrie

Executive Vice President, Cloud + AI, Microsoft

Search every verified Scott Guthrie interview, podcast appearance, and on-the-record quote — each transcript cross-checked by AI and human review to confirm speaker identity. Scott Guthrie, Executive Vice President of Microsoft's Cloud and AI Group, discussed the company's new Maia 300 custom AI chip in an October 2026 interview. He stated that the chip delivers 40% more AI performance per megawatt than leading GPU systems and that Microsoft designed it to require no changes from customers, who would benefit transparently in performance and cost savings. Guthrie said Microsoft is in discussions with various AI labs and partners about using Maia chips, but had no announcements at the time. He also emphasized the importance of building cloud infrastructure globally, with attention to security, sovereignty, and cost-effectiveness. At the World Governments Summit in February 2026, Guthrie described a shift toward autonomous or agentic AI, where AI agents complete tasks with less human intervention. He cited an internal Microsoft example of an AI agent managing fiber-optic cable repairs by communicating with telecom partners. Guthrie said he does not expect a winner-take-all outcome in AI, noting multiple silicon chips, models, and use cases, and suggested that organizations adopting AI quickly to drive change would be the biggest winners, drawing parallels to the internet and smartphone eras.

Recent appearances

  • Microsoft Unveils Maia 300 | Cloud Chief Scott Guthrie Live

    Microsoft is unveiling Maia 300, its latest custom AI chip, as the race to deliver more AI runs up against limits on power and data center capacity. Microsoft’s Cloud & AI chief Scott Guthrie joins Deirdre Bosa for an exclusive live interview today. We’ll discuss what Maia 300 means for Microsoft’s AI ambitions, its reliance on Nvidia and AMD, and how the rise of custom chips could reshape the AI trade. Live interview Monday, October 12 at 12:45 pm PT / 3:45 pm ET

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  • Who Will Win the AI Race? | Scott Guthrie - World Governments Summit

    "What happens when AI stops waiting for instructions and starts taking action on its own? Scott Guthrie, Executive Vice President, Cloud and AI Group at Microsoft, explores the next major shift in artificial intelligence: autonomous and agentic AI. While today's AI tools often respond to prompts, AI agents can be given a task and work toward completing it with much less human intervention. Guthrie explains how this could transform business operations, government services and the way organizations get work done. He shares a real-world example from Microsoft, where an AI agent communicates wi…

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  • What’s real, ready, and next for developers with Scott Guthrie | LIVE109

    There’s a lot of noise about AI. In this quick-paced fireside chat, get the builder’s perspective on what actually matters for developers. Drawing from how Microsoft runs a complete system from silicon to software at global scale, Scott breaks down the evolution across AI-ready infrastructure, context layers for agents, and what AI-assisted modernization means for developers. 𝗦𝗽𝗲𝗮𝗸𝗲𝗿𝘀: Scott Guthrie Seth Juarez 𝗦𝗲𝘀𝘀𝗶𝗼𝗻 𝗜𝗻𝗳𝗼𝗿𝗺𝗮𝘁𝗶𝗼𝗻: This is one of many sessions from the Microsoft Build 2026 event. View even more sessions on-demand and learn about Microsoft Build at https://build.microsoft.co…

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  • Microsoft Ignite '25 Keynote | Scott Guthrie, EVP Cloud and AI

    Scott Guthrie presents Microsoft Azure as the infrastructure powering all of Microsoft's cloud and AI services. He highlights Azure's global footprint with 70 regions worldwide and data residency in 33 countries. Guthrie unveils a new Azure AI data center in Atlanta filled with NVIDIA GB300 GPUs, delivering 10 times the performance of the world's fastest supercomputer while using renewable energy and zero water waste technology. The presentation covers key Azure services that power AI applications, including AKS (Azure Kubernetes Service), Cosmos DB, and the newly announced Horizon DB for Pos…

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  • Data centers use HOW much water? Microsoft's Scott Guthrie explains

    What does it take to build infrastructure that powers frontier AI models with trillions of parameters? In this episode of The Neuron Podcast, Corey Noles sits down with Scott Guthrie, Executive Vice President of Microsoft's Cloud + AI Group, to explore the engineering behind Azure's AI Superfactory. Scott leads Microsoft's hyperscale cloud computing solutions including Azure, generative AI services, data platforms, and business applications. Since joining Microsoft in 1997, he's been instrumental in shaping the company's cloud, server, and development technologies. We explore Microsoft's i…

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  • Microsoft's Cloud & AI Head on the AI Buildout's Risks and ROI — With Scott Guthrie

    Scott Guthrie is the executive vice president of Cloud and AI at Microsoft. Guthrie joins Big Technology Podcast to discuss the tech industry's massive AI infrastructure buildout and whether it is overdoing it with the hundreds of billions of investment. Guthrie discusses the way Microsoft thinks about its OpenAI investment, whether it's worth investing in scaling pre-training, and Silicon Valley's growing debt problem Tune in for the second half where we discuss the longevity of the GPU, custom silicon, and competing with NVIDIA. Chapters: 00:00 The AI Investment Surge 02:59 Microsoft's St…

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  • 50 Years of Microsoft and Developer Tools with Scott Guthrie

    How has Microsoft changed since its founding in 1975, especially in how it builds tools for developers? In this episode of The Pragmatic Engineer, I sit down with Scott Guthrie, Executive Vice President of Cloud and AI at Microsoft. Scott has been with the company for 28 years. He built the first prototype of ASP.NET, led the Windows Phone team, led up Azure, and helped shape many of Microsoft’s most important developer platforms. We talk about Microsoft’s journey from building early dev tools to becoming a top cloud provider—and how it actively worked to win back and grow its developer base…

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  • Microsoft Build 2025 Keynote | Scott Guthrie Demo, EVP Cloud and AI

    At Microsoft Build 2025, Scott Guthrie, Executive Vice President of Cloud + AI, delivered a keynote emphasizing Microsoft's commitment to integrating AI across its platforms. Key highlights from his presentation include: 1. Azure AI Foundry Expansion: Guthrie introduced the general availability of Azure AI Foundry, a platform supporting over 1,900 AI models with enterprise-grade multi-agent orchestration, enabling developers to build and deploy AI solutions at scale . 2. GitHub Copilot Advancements: He showcased enhancements to GitHub Copilot, transitioning it from a code completion tool to…

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  • DEVintersection Fall 2022 - Scott Guthrie Keynote

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  • Fireside Chat with Scott Guthrie and Alysa Taylor: How Customers Build Agility and | KEY02H

    Join Microsoft leaders Scott Guthrie, EVP, Cloud + AI Group, and Alysa Taylor, CVP, Industry, Business Applications, and Data & AI for a wide-ranging discussion, as they share their insights about how our customers and partners across industries are innovating, driving business impact, and realizing faster time to value with the Microsoft Cloud. To learn more, please check out these resources: https://aka.ms/learnatignite https://info.microsoft.com/contact-us... Speakers: Alysa Taylor Scott Guthrie Session Information: This video is one of many sessions delivered for the Microsoft Ignite…

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  • Devs Conference Keynote with Scott Guthrie

    Keynote with Scott Guthrie Microsoft Power Platform documentation: https://docs.microsoft.com/en-us/powe... Fusion Development Learning Path: https://docs.microsoft.com/en-us/lear... Power Apps Webinars: https://docs.microsoft.com/en-us/powe... Power Apps Developer Plan: https://powerapps.microsoft.com/en-us... Powerful Devs Conference Cloud Skills Challenge: https://docs.microsoft.com/en-us/lear...

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  • Microsoft: Into Focus with Scott Guthrie Scott Hanselman Rajesh Jha and Kevin Scott | KEY11

    Join hosts Filisha Shah, Seth Juarez, and Microsoft Partner Program Manager Scott Hanselman for a fun-filled rundown of executive content, roundtable conversations, coding demos and more. Scott Guthrie, Microsoft EVP of Cloud & AI, will recap key news from Day 1 on the breadth and depth of the Microsoft Cloud; Scott Hanselman will showcase Microsoft’s latest developer resources; Rajesh Jha, Microsoft EVP of Office, will discuss developer opportunities in the Microsoft 365 stack; and Kevin Scott, Microsoft CTO, will show how AI and machine learning are becoming critical tools for every develope…

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Notable quotes

“I think one of the things that certainly everyone's seeing right now is some of the massive improvements that AI has realized in terms of capability the last really going back the last three or four years but especially just even the last six months or 12 months. If you look at coding scenarios today versus this time last year, it's massive improvements. It's not like 20 or 30 or 40% improvement. It's probably five o”

“I think ultimately at Microsoft, we believe that really the future of AI is going to be defined by who can deliver AI that's scalable, affordable, and accessible. And ultimately AI that's trusted by customers in the world that use it. And as Microsoft we're really focused with our Azure business in being the cloud platform for millions of customers around the world serving billions of users and core to that has been ”

“I think in our earnings report, you know, we kind of quoted that we added over a GW of data centers in 90 days and, you know, gigawatts a lot, it's like the size of Seattle. And so it's, you know, we're, we're growing fast and we're doing it, as Satya talked about in the keynote, responsibly, our data centers are 0 water waste. So you know, they, they use less water than a restaurant does in an annual year. And you k”

“People often ask me like what about water consumption? It's about 20 houses worth of water to fill the data center. So 20 American homes. So in the grand scheme of things, it's not a lot of water. And then once we fill the data center, we will not replace the water for at least six years. So there's no evaporation. There's no water loss. It's continuously recirculated, working like a radiator system in a car. It's a ”

“The new Fairwater data centers that we're building, and we're building some in Atlanta and Wisconsin, are two areas that we've both kind of disclosed, and there's lots of other sites around the US and the world that we're doing stuff to. They are the densest concentration of GPU power in the world. And by densest I mean the most GPUs and then the most GB Grace Blackwell GPUs, the latest, all liquid cooled, which mean”

“I think we definitely are not nearly at the point at which there is too much AI infrastructure given I think the number of AI workloads that are coming for the world. And I think we're seeing over the last couple years as people use AI they get value they use it more the models get better and people then use it even more for new use cases and I think at this point across the industry with AI we're still more supply c”

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The summary and quote tags on this profile are produced with AI assistance from verified, first-person interview transcripts, then checked by our team to confirm the speaker's identity and the accuracy of every quote. See how we verify →