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Lisa Su
Chair, President & Chief Executive Officer, Advanced Micro Devices

Building the Next Era of AI Infrastructure

📅 Oct 13, 2026 Open Compute Project 27 MIN 335 VIEWS 45 SEGMENTS · 1 SPEAKERS
Dr. Lisa Su Chair and Chief Executive Officer - AMD.Uh actually this is uh AMD has been a long-standing supporter of OCP but this is actually my first time at the OCP um global ...

What Lisa Su said

Written from the verified transcript and checked against it. Every figure links to the moment it was said.

Lisa Su, CEO of AMD, spoke at the OCP Global Summit about the rapid evolution of AI infrastructure. She highlighted the shift to inference, noting a 95x increase in tokens per month over two years and that inference now represents about 60% of the market. Su discussed AMD's Helios rack, launched in July 2026, which uses the OCP Open Rack Wide standard and is co-engineered with Meta. She reported Helios is in production, with systems installed at OpenAI, Meta, Microsoft, Oracle, and Anthropic. Su also introduced the new Helion Agentic AI rack, designed for agentic workloads, and announced new EPYC Verano silicon, optimized for low power, with production expected in the first half of 2027. She emphasized AMD's commitment to open ecosystems and collaboration.

Key takeaways

  1. Inference now represents about 60% of the AI market in 2026, with agentic traffic growing 14x this year.
  2. Helios rack, launched July 2026, is in production with first systems at OpenAI, Meta, Microsoft, Oracle, and Anthropic.
  3. New Helion Agentic AI rack offers up to 32,000+ Zen 6 cores, 40% more than competitive racks, available from November 26.
  4. New EPYC Verano CPU, optimized for low power, will be in production in the first half of 2027.
  5. AMD raised its CPU TAM estimate three times in nine months, now expecting over $200 billion by 2030.

Numbers and commitments

FigureWhat it refers toTypeAt
95x increase in tokens per month over past two years metric 3:41
60% share of AI market that is inference in 2026 metric 4:53
14x growth in agentic traffic this year metric 5:24
$200 billion CPU TAM by 2030 guidance 6:47
72 GPUs in Helios rack working as single accelerator metric 10:45
18,000 GPU compute units in Helios rack metric 10:45
4,600 Zen 6 cores in Helios rack metric 10:45
30% more tokens per dollar with Helios metric 15:19
32,000 Zen 6 cores in Helion rack metric 22:13

Chapters

  1. 0:00Opening and OCP collaboration
  2. 3:05AI market demand and inference growth
  3. 6:12TAM projections for accelerators and CPUs
  4. 9:35Helios rack architecture and launch
  5. 13:25Networking and software ecosystem
  6. 16:46Helios production and customer adoption
  7. 18:04Agentic infrastructure and Helion rack
  8. 24:40New EPYC Verano silicon
  9. 26:25Closing remarks on open ecosystem
Lisa Su 0:03 ↗
All right, good afternoon everyone. How is everyone doing? I have heard that this is the place to be. Actually, AMD has been a long-standing supporter of OCP, but this is actually my first time at the OCP Global Summit, and I have to say I'm just blown away by the scale of what we have here. So I want to congratulate George and really the entire organizing committee for putting together just a fantastic event.
So today, what I'd like to do is maybe talk a little bit about what we see at AMD in terms of what's happening in the market. I can say for sure it's the fastest moving market that I've ever seen. So much change, so much innovation, so much collaboration. And maybe from an overarching standpoint, I would say, you know, for all of us at AMD, we wake up every day thinking that our job is to really push the boundaries of high performance computing so that we can solve some of the most important challenges and problems in the world.
And to do this actually requires intense collaboration because I'm a big believer in there is no one company that has every answer to every solution. And frankly, the more we can bring the best of our companies together, the better we're going to do as an industry. And so AMD has open as a foundation of our principles. It's one of the things that we think about when we develop technology. It's one of the things that we think about when we develop our roadmap. And when you look at the last 15 years of what OCP has really done, it's really been a huge part of our development roadmap going forward.
First on our open server platforms from our very first platform that we did with Naples back in 2017. That was a very close collaboration with our partner Microsoft, but together we brought it to OCP. When you look at, you know, over the last few years, a lot of work has come together on the networking side with the Ultra Ethernet Consortium, with the work that we're doing around, you know, UALink and UALink Ethernet. All of those are really important things for interoperability.
I'm excited to talk about Helios, so we're going to talk a little bit about Helios today and the progress on that rack scale solution, which is again based on OCP standards. And then looking forward, I think we have lots more opportunities to collaborate together, and these also become, whether you're talking about MRC or OCP, these are also areas where there's just a tremendous opportunity for us to come together as an ecosystem. And with the notion of when we come together as an open ecosystem, we will actually accelerate the pace of innovation and get better solutions for our joint customers.
So, a little bit about the market. I think you guys know very well the AI market is truly transforming every part of the world, every industry that we're in, whether you're talking about healthcare or manufacturing or science. We're seeing much, much more capability come across. I like to say that we're in a world where computing equates to intelligence. And if you have the chance to be more intelligent, why wouldn't you try to get more capability? And that's really what we're trying to do in terms of bringing all of that into the ecosystem.
And just a few of the demand numbers that you see, every time I look at these charts, they tend to keep going up and to the right. And people are always asking, well, you know, are we sure that we're doing productive work with all of the AI compute that we're putting on board? And the answer is absolutely yes. I mean, we are doing a tremendous amount of work. We're getting more and more productive each time. You kind of look at some of these demand numbers and you see like a 95x increase in tokens per month over the past two years. We're now at some number like almost 40 quadrillion inference tokens a month.
When you think about what that means in terms of useful AI, we get a lot of different data, but I think the data that's most important to me is what do I see when I talk to customers and when I spend time with the largest users. You know, clearly training continues to be extremely important and we're going to continue to need the largest training clusters in the world and we're going to continue to push the envelope on capability, let's call it, you know, 5x increase every year since 2020. And that doesn't look like that's going to change. That's going to continue going on.
But we've always thought that where AI really pays off is when inference overtakes training. And when you look at the numbers over the last few years, especially this year in 2026, this year is really the year of inference. This is the year where we believe inference is now about 60% of the market going forward. And it's not just inference, it's really the agentic workloads that have really taken off.
So you look at some of these numbers. This is some new data from OpenRouter, which routes requests across many models. And what you see is that the amount of human traffic has gone up steadily. But what's really grown is the amount of agentic traffic. And we're seeing a 14x growth just this year in the amount of agentic traffic that is going through. And that kind of tells you the power of AI working. We're training better models. We now have the opportunity not just to do inference, but we have the opportunity to solve problems. And with that, we're seeing a lot more opportunity for growth and, you know, really productive growth going forward.
Now George showed some numbers about the TAM as it relates to the infrastructure. This is some information on the TAM as it relates to the silicon and the systems, which is what, you know, we're focused on. And we're seeing a couple things, right? First of all, we're seeing the data center AI accelerator TAM grow to close to one and a half trillion by the time we get to 2030, which is a fantastically large number. That's why there's so much excitement and innovation in this area.
But we've also seen that with agentic workloads, we've seen a very significant increase in what was known as the traditional CPU TAM. If you were to look at this number, you know, let's call it even a year ago, you know, people would have said, hey, the CPU market is probably a 20 billion market growing, you know, single digits over the next few years. And we have actually raised the TAM on this three times in the last nine months because we've seen that much growth in the overall CPU demand, which we now believe will grow at approximately 50% CAGR over the next four or five years to over a $200 billion TAM by the time you get to 2030.
And that has implications on how you want to build systems. The fact is, you know, there's no one-size-fits-all when it comes to compute. You actually need the right compute for the right workload. And that's across CPUs and GPUs and ASICs and FPGAs and all of the mix in between. And that's a foundation of how we have, you know, really focused at AMD.
So when you think about, you know, the three things that we think are most important, the first and foremost is we're a compute company. Compute equals intelligence. We need to have compute leadership, and that compute leadership is across every aspect of that, you know, CPU, GPU, ASIC, all of those capabilities because we need the right compute for each application.
We also believe that you're going to see AI everywhere. So we're going to spend a lot of time over the next few days probably talking about the big iron in the cloud, hyperscale, and enterprise. We're a big believer in the fact that you're going to see AI infused through every aspect of the edge as well as the client in the ecosystem. And the more that we can get the standards across those different form factors to be the same, the more that we can get the software to work across all of those systems, the better off we're going to be to provide productivity to the end users of these systems.
And then the middle point is the point that's most relevant for today. Open is a foundation of what we do at AMD. We are big, big believers, as I said, in the idea that open platforms enable collaboration. Collaboration enables the best of each company to bring to the table so that we have better overall solutions. And the fact is, you know, AI at scale is a team sport. It is an area where we want to bring the best of the industry together.
So I'll talk a little bit today about the work that we're doing on rack scale innovation because it's been a very, very exciting year for us, and then a little bit about what we see going forward in terms of the agentic infrastructure. So, you know, first and foremost, I think all of you guys know this, but, you know, this has been a principle: frontier AI has higher and higher demands on what all of us do.
You know, our job is to bring a solution to the market that allows our end users to use the technology as fast as possible, as efficiently as possible, with as little friction as possible to get the best tokens per dollar, to get the best tokens per outcome. And to do that, you need all of these pieces. You need to have leadership compute. You need to have an open rack architecture. You need to have a fabric that allows you to scale across the systems. We also need to care about things like efficiency and serviceability as well as, you know, overall turnkey solutions.
So you need all of these things, and I have to say all of these things were critical when we decided to bring out the Helios architecture. We launched Helios in July of this year, just a couple of months ago. I will say, you know, our view is that this is the highest performance AI rack in the industry. 72 GPUs working together as a single accelerator. More than 18,000 GPU compute units, 4,600 Zen 6 cores. Each compute tray is just a little bit heavy at 160 pounds, and the total rack is nearly 7,000 pounds. So, it's a little bit of a machine.
I think George said something like everyone gets a little wider as the years pass. I don't want to say that about our racks, but I would say we made a very deliberate choice with Helios to use the OCP Open Rack Wide standard. It is one of the most ambitious engineering feats that I've ever had a chance to be part of in my career. This was co-engineered with Meta, our partner. I know you're going to hear from Santosh a little bit later on. I have to say it has been a tremendous partnership.
And, you know, we started with the notion of, look, there are going to be a lot of accelerators out there. It is not one-size-fits-all. It's not, you know, one company has all the best parts. What we want to do is make it really easy for a heterogeneous data center environment because there's a firm belief in that you're going to need a mix of CPUs, GPUs, purpose-built ASICs. They're going to want to be in a similar data center environment. You're not going to want to switch out every component every time you change an accelerator. You're really going to try to standardize as much as you can so that you are differentiating on the things that make the most difference.
And that's exactly what we've done with the Helios platform together with Meta. I think what we see here is a tremendous opportunity to bring the ecosystem together. So lots and lots of partners are needed to make Helios happen, but it includes the open architecture on the rack standpoint, open power shelves, open networking, and the overall management system. So we're very happy with how Helios has come along.
As part of this, networking is a huge piece of this ecosystem. I would say that we've spent quite a bit of time internally, you know, Forrest Norrod, who runs the data center solutions for us, in terms of architecting this whole thing coming together. But our principle is we wanted to use the best solution that was available, and the best solution that would be available would mean bringing in the leading networking partners in the world. We're doing tremendous work with Broadcom, Cisco, Arista, HPE, DriveNets, and the idea is to have leading front-end solutions, leading scale-up solution with UALink over Ethernet as well as UEC, and then leading scale-out solutions as well that are ahead of the industry. And all of this is delivered through the OCP open ecosystem.
And all of this openness extends to software as well. So the idea of software is, you know, we need to make sure that it's super easy for our customers to bring new workloads onto our accelerators. And to do that, you want to have, let's call it, the leading open communities running natively. We have the top 15 open AI communities that are supporting AMD natively. We have seen significant benefit.
Perhaps this is one of the largest benefits that we've seen of AI. This is a case where, you know, agentic AI can actually continue to make the performance of the hardware better over time. Just to give you one statistic, Hyperloom is our agentic AI solution, and we've had it running continuously running for the Hugging Face models. So over 14,000 models on Hugging Face with no humans in the loop. We've seen almost a 40% improvement in performance just having the agentic AI run.
So the key is open ecosystems on hardware and software bring the opportunity to get significant performance capability to our end users. So if you take a look at all of those pieces, what does that mean to the end user? The Helios rack delivers the highest compute in the industry, the highest memory capacity, the highest memory bandwidth, and the highest networking capacity or capability across the industry. And to give you some idea of the numbers, we believe that we're translating into 30% more tokens per dollar using the Helios solution. Now, all of PowerPoint sounds great. It's probably better to see a few pictures. So, let me show you a little bit here.
People told me that rack scale solutions would be the hardest thing that we've ever done. I think they were absolutely right. Helios is absolutely the most sophisticated and complex system that we have built at AMD together with our partners. But I'm very happy to say that Helios is in production today. We started shipping production in September. The first systems are installed at our leading customers: OpenAI, Meta, Microsoft, Oracle, Anthropic, and we continue to see just tremendous learnings when we bring all of these pieces together.
So our production will continue to ramp through the fourth quarter into the first half of next year. But what we did is, you know, with the OCP standard working together with our partners was just fantastic engineering overall. I'm happy to say there's significant growing adoption of Helios, not only the largest model companies, but in addition a number of AI-native companies, a number of the overall ecosystem ODMs, OEMs, I know a bunch of you are in the audience today, NeoClouds. Thank you. Thank you for all of the collaboration on Helios. We're going to continue to broaden this going forward as we, you know, think about, you know, the next few quarters.
So with that, maybe I'll transition a little bit to agentic infrastructure, and I would say that this is probably the place where there's been the most activity over the last, let's call it, six months or so. There's been a lot of talk about agents. I would say the excitement is real. I think we've all seen just tremendous productivity, whether in personal use cases or in the enterprise use cases, and it's moving much faster than we thought.
So kind of some of the examples out there that are pretty interesting. You know, MetaMuse has kind of recaptured the imagination as to what AI can do for the consumer. This number of 5 million downloads of MetaMuse was as of the end of September. So that was like the first, you know, couple weeks. I'm sure Santosh will talk about it more. I think I read this morning in the Wall Street Journal that they're now up to 9 million downloads of MetaMuse in, you know, just the first month or so.
You know, OpenAI has talked about using 10,000 agents to solve some of the most difficult math problems in history that haven't, you know, really seen the full solution. Anthropic talks about using R&D agents to really get a claw working. All of these say that agentic usage is real. I can tell you within AMD, we're actively using agents both on our silicon development as well as on our software development. I gave you the example of Hyperloom.
So you say, okay, everyone talks about agents, but what do you actually need for agents? And I think the most important thing to realize is that agents actually are not one thing. You know, agents, like people, there are lots of different types of agents. You need the right agents for the right application, and for that, you actually need the right compute.
So when you're talking about personal agents, you probably want the densest agents possible. These are simpler tasks, and you want them to be, you know, very efficient. You want them to be maximum number of agents per watt, so you are saving your power correctly. You know, that's one class of agents. You talk about enterprise agents where you're doing a lot of different types of activities, and so you want them to be pretty balanced. Or you're talking about some of the hardest compute problems out there. These technical compute agents, you're going to want them to be bleeding edge performance, kind of the best of the best.
And so each of these agents needs a different type of compute. And what we believe is each of these agents also need the right type of rack. And that means you're going to see a certain type of rack in hyperscale environments where you might have disaggregated CPU and GPU racks, whereas in enterprise you might want to see more all-in-one racks going forward.
So I'm happy to say this morning we announced the AMD Helion Agentic AI rack. Helion is the cousin to Helios, and it's really focused on the agentic AI compute aspect of it. What we're trying to do here is frankly do what is easiest in terms of bringing all of the pieces of the open compute infrastructure together so that we can get the most efficient CPU racks. So that is, you can use a combination of CPUs and GPUs.
We're also integrating it with a token router. I think everyone is talking about how can you most efficiently route your overall AI usage. I know that within our own IT infrastructure, the idea is you don't need the same model for every question. You don't need the same compute for every question. You want to be able to route the right model and the right compute for the right application. And that's a key piece of this as well as the overall open environment.
So, a few of the things about our Helion Agentic AI rack. The nice thing about Helion is we've used practically everything that we could through OCC OCP specs with the idea of it's a standard 21-inch rack. It can be liquid or air cooled. It is up to 32,000 plus Zen 6 cores, which is 40% more than the other competitive racks. It's the highest compute density in the industry. It also can hold up to 32 Instinct MI350X GPUs as well as a tremendous amount of networking capability. So it's all coming together in an open compute standard.
And when you look at how we expect these to be used, when you start in a hyperscale configuration, given the density of compute in hyperscale, you would imagine that you would have significant, you know, GPU racks in one, you know, portion of the data center or one part of the deployment, but you can have your agentic CPU racks, you know, really sitting side by side, and you can mix and match the type of CPU nodes in it. So whether you're looking at personal agents or enterprise agents or technical agents, you can pick the right compute for the right workload.
And in the enterprise configuration, you can actually add another piece of this, which is, you know, a lot of enterprises are probably, you know, not running the most advanced foundational model, at least when they're running them on-prem. They could be actually wanting to have the ability to have both CPUs and GPUs in the same rack optimized for their particular workload. And so that is what we can do with the Helion rack.
And I'm happy to say that there's been tremendously positive response to our agentic rack. So, you know, two pieces: one is we have a rich ecosystem that are offering the Helion rack starting November 26, and all of this is going to be contributed to OCP. So, you know, very excited for that.
Okay, so in the final few minutes, I thought I would just give you an update on our silicon. We are always pushing the bleeding edge of silicon. As I said, in July we talked about our Venice portfolio and our Venice family. We believe these are the best server portfolio for agentic racks because we have the ability to really mix and match for the right workload. We talked about the various flavors of Venice, including our workhorse for our agentic CPU servers, the Venice 256-core, our general-purpose CPU servers, as well as our CPUs for host nodes, the Venice high frequency.
And all of that is great, but when I saw you in July, I showed you four pieces of silicon. And we have some new silicon to show you today. So, let me show you. Here we go. This is our new EPYC Verano.
Verano is based on the Venice family of CPU cores. This guy is actually optimized for the lowest system power. So it actually has six CCDs, or six CPU core dies, that have 32 cores each, up to 192 cores. And with that, we've also updated the CPU to GPU bandwidth, which makes it exceptionally good for head node solutions as well. So Verano looks fantastic. There's a lot of excitement about Verano as well as the rest of the Venice family, and we will be in production in the first half of 2027.
So with that, let me conclude and say, look, we love OCP. We love the open ecosystem. Open is a foundation for what we care about at AMD. It is open on every level. It's open on the hardware level. It's open with specs. It's working with our partners. It's open on the software level, working with all of the software vendors to ensure that we are bringing that together, and it's open on the ecosystem side as well.
So I'm very happy to say a lot of our partners are here at OCP this week. I think it's fantastic all of the work that's coming together and all of the learnings that we will get from bringing the teams together. So again, I want to say a big thank you to OCP for really bringing together this, what I would call, collaboration at scale. It's an opportunity for each of us to innovate on the things that we're best at, and also for each of us to bring together all of the components across the industry so that we can get solutions to the market faster. So with that, thank you very much. Have a great OCP.

Cite this transcript

APA, MLA, BibTeX
APA

Su, L. (2026, October 13). Building the Next Era of AI Infrastructure [Interview transcript]. Open Compute Project. CEOInterviews.AI. https://ceointerviews.ai/interview/3051249/

MLA

Lisa Su. "Building the Next Era of AI Infrastructure." Open Compute Project, 13 Oct. 2026. Transcript, CEOInterviews.AI, https://ceointerviews.ai/interview/3051249/.

BibTeX
@misc{su2026_3051249,
  author       = {Lisa Su},
  title        = {Building the Next Era of AI Infrastructure},
  howpublished = {Interview transcript, Open Compute Project. CEOInterviews.AI},
  year         = {2026},
  month        = {oct},
  url          = {https://ceointerviews.ai/interview/3051249/},
  note         = {Speaker-attributed transcript with timestamps}
}