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Anish Acharya
General Partner, Andreessen Horowitz

Will OpenAI or Anthropic kill your startup? : Anish Acharya a16z

📅 Oct 22, 2026 Venture Europe 20 MIN 4 VIEWS 51 SEGMENTS · 3 SPEAKERS
Anish Acharya, General Partner at Andreessen Horowitz, joins the show to discuss the shifting landscape of modern business. We explore how AI advancements have lowered the barrier to entry for developers and founders, making it easier than ever to bring ideas to life. Subscribe for weekly conversations with the founders and investors building the next generation of businesses. This interview was a side event organised by ⁨@a16z⁩ during the Wave by Vento conference in Turin October 7-9 2026 ⁨@vento_ventures⁩ ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ ❤️ SUPPORT THE SHOW — OUR SPONSORS Leapsome: The Age...

What Anish Acharya said

Written from the verified transcript and checked against it. Every figure links to the moment it was said.

Anish Acharya, general partner at Andreessen Horowitz, said that having a pitch without a prototype is no longer acceptable; founders must come with a product that can't be ignored and ideally be in market. He argued that the risk of OpenAI or Anthropic copying a startup's feature is overestimated, citing that a venture firm missed all of tech in the 2000s thinking Google would win it all. Acharya advised being extremely ambitious long-term but narrow short-term, monopolizing a small niche like Facebook did at Harvard. He estimated only 10 million people are responsible for all AI consumption worldwide, illustrating how early we are. He said coding is now an industry with a dozen winners, not a market with one. He recommended reading Seven Powers for moats and cited Cursor as an example of a moat emerging over time. He encouraged founders to be on X and look for an 'earned secret' showing intentionality. He also said moats can't be designed on day one.

Key takeaways

  1. Only 10 million people are responsible for all AI consumption worldwide, showing how early the market is.
  2. Coding is now an industry with a dozen winners, not a market with one winner.
  3. Monopolize a small niche, like Facebook at Harvard, before expanding to adjacencies.
  4. Moats cannot be designed on day one; they emerge over time, as with Cursor.

Numbers and commitments

FigureWhat it refers toTypeAt
10 million People responsible for all AI consumption worldwide metric 9:39
$500 Example price to test willingness to pay price 12:00
1% Share of market that is hard to get in a horizontal market metric 7:39
80% Share of a small market to aim for metric 7:39
50% Share of technology market IBM had in its heyday metric 10:50
60 billion Exit valuation of Cursor metric 13:29
Christmas 2009 When the company added a million users timeline 16:57

Chapters

  1. 0:00Pitch requires a prototype
  2. 1:50AI as human technology
  3. 2:46Toys as early signals
  4. 4:38Embarrassment and Canadian storytelling
  5. 6:36Pre-seed metrics and market focus
  6. 9:39How early is AI adoption
  7. 10:50Feature copied by OpenAI or Anthropic
  8. 12:00Moats and Seven Powers
  9. 13:29Cursor example of emerging moat
  10. 15:53Creativity as bottleneck

Questions asked in this interview

12
  1. 0:02So do you think that now that it's very easy to build with AI, that creativity is the bottleneck?
  2. 0:29How do you look at that?
  3. 0:48What's one thing that they should be doing differently Monday morning?
  4. 1:33Yeah, I was wondering, what is the background of that? What made you write that?
  5. 3:50What would be like your advice for, you know, maybe founders in this room that kind of feel this shame and embarrassment, that they don't know what to do, because everything kind of looks like a play or like a toy?
  6. 6:20How do you assess team, product, traction?
  7. 7:12How do you look at the market?
  8. 9:04You know, how early or how too late are we?
  9. 13:16Do you have some examples of entrepreneurs, of companies that you've seen recently that managed, let's say, to create this really great workflow on top of a model in a niche that had high willingness to pay?
  10. 14:17When I think about a toy, what do you think the toys in AI will be?
  11. 16:29How many people in the room are founders?
  12. 18:07How should they think about the storyline and narrative?
Anish Acharya 0:00 ↗
Having a pitch without a prototype is no longer acceptable.
Caroline 0:02 ↗
So do you think that now that it's very easy to build with AI, that creativity is the bottleneck?
Anish Acharya 0:09 ↗
I mean, to some extent, ambition, creativity, resilience. It's really funny because we always lionize the people that did two things: that wrote code and that made movies or did creative work. We always said, 'Wow, if only I could do those things, I would do them.' And now three years later, we have these models and anyone can do it, and yet it's the exact same people that are doing those things.
Caroline 0:29 ↗
Do you actually sometimes think, is this a feature that can be copied by OpenAI or Anthropic? How do you look at that?
Anish Acharya 0:35 ↗
No, I think we overestimate the probability of that. You know, there's a sort of venture firm that I won't name, but they famously missed all of tech in the 2000s because they thought that Google was just going to win it all. And I think this mistake gets made over and over again.
Caroline 0:48 ↗
What's one thing that they should be doing differently Monday morning?
Anish Acharya 0:52 ↗
Oh, you have the wand. You got to build a thing that can't be ignored, that gets to scale, that follows some of the patterns that I described. And I promise, like, you don't have to email me — I'll be emailing you.
Caroline 1:03 ↗
Yeah. Yeah. Yeah.
And together this evening, I have with me Anish. He is a general partner at a16z, focusing on investing in AI-native companies. He's actually a serial entrepreneur. I know that a lot of people think that they're serial entrepreneurs, but you have founded SocialDeck, sold it to Google also. So you have founded Snowball, sold it to Credit Karma.
Anish Acharya 1:24 ↗
That's right.
Caroline 1:25 ↗
Congrats.
Anish Acharya 1:26 ↗
Thank you.
Caroline 1:27 ↗
So they have like a proper founder.
Anish Acharya 1:29 ↗
I mean, the story — it feels a lot better when you read it on LinkedIn than living it, you know.
Caroline 1:33 ↗
We can start actually with a recent article that you have posted. It kind of gained, I think, like a million views — like, that AI is one of the most human technology ever made. Yeah, I was wondering, what is the background of that? What made you write that?
Anish Acharya 1:50 ↗
I mean, honestly, it's a little bit exhausting, like all of you, that every article I read about AI, especially in the mainstream media, is about jobs, right? Are we gaining them, are we losing them? And whether we are or we aren't, just so boring to constantly read about the same thing over and over. I think for so many of us that grew up loving software, for us, software was a medium for self-expression, right? If you're building a game for yourself, if you're tinkering on something, so many of these things were not about economic importance, right? Economic importance was like a nice side effect. So I think that's the thing that's being discussed about AI, which is like, hey, the skill is being divorced from the ambition. If you want to make it, you can. And that's a pretty cool thing for, you know, just for human self-expression and flourishing. So that's really what inspired me to write the post.
Caroline 2:35 ↗
This kind of touches a little bit about, you know, like the next big company is going to look like a toy in the beginning. What do you think — what looks like a toy now in the AI world?
Anish Acharya 2:46 ↗
Yeah, so this is a famous Chris Dixon-ism. If you haven't all read his posts, you definitely should. He's sort of, you know, he's upstream of a lot of our thinking at the firm, and really in the industry is one of the best consumer investors. And, you know, when he famously said that some of the best businesses start out looking like toys, I mean, look at Discord, look at Oculus, look at, you know, a lot of the big social products — they were dismissed as silly or non-serious.
And so I think this is a very important thing for all of us to embrace, which is, as you guys know, being a founder is a highly embarrassing exercise, right? Your friends and family don't know what you do, your parents — you can't really explain it to them. People secretly worry that you were fired from your job, or at least they did for me. But I think that's actually where a lot of the alpha is. So the things that interest us most, which are often things that feel like toys, are signals to us about kind of demand and intuition. And when we try to build serious things with a capital S that, you know, maybe would make for a good MBA case study, those things never tend to work out. But that's been my kind of empirical observation.
Caroline 3:50 ↗
I remember I just talked with a founder and he was about to go on stage, and I was like, 'Oh my god, like, wonderful. You're doing so great.' And he's like, 'Look, Caroline, like, the first five years I looked very stupid. No one believed it. And now, like, the last five years I look like a genius.' Yeah. There's no, like, in between. And you also, you kind of mentioned the embarrassing fact. I know there is actually a big difference between, let's say, Europe and the US when it comes to shame. In the US, if you try to build a business and it kind of doesn't work out, it's still — you're appreciated. Whereas, like, in Europe, maybe if you fail, that type of embarrassment maybe has like a different nuance. What would be like your advice for, you know, maybe founders in this room that kind of feel this shame and embarrassment, that they don't know what to do, because everything kind of looks like a play or like a toy?
Anish Acharya 4:38 ↗
Well, I think a lot of this is self-perception, but I understand the culture because I built my first company in Canada. I love Canada. I'm a proud Canadian, but it's a different environment. You know, it's a cautious environment. It's an environment in which it's impolite to, you know, to be too bold sometimes. And I noticed actually when I came to Silicon Valley, when I was pitching, I got this advice from another Canadian founder who'd been very successful. And he said, 'You're pitching this company like a Canadian would, which is you're telling me everything that you're definitely going to do, and I believe you, but when I hear it, it sounds unambitious.' He's like, 'Look, this is how Americans tell their story: they tell you something that feels insane, and then they try like hell to make it happen.' And that's the sort of style of storytelling that Silicon Valley investors expect. And that's not delusion, right? That actually has to be grounded in some reality, some belief, some kind of a tangible plan. So I think there are these sort of social norms and cautions, but a lot of it is in our own heads, because if you go on X and you post about whatever you worked on that didn't work in an earnest way, I bet you'll get more positive comments than negative ones.
Narrator 5:40 ↗
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Caroline 6:20 ↗
And also, you guys invest from pre-seed, or you particularly like to invest from pre-seed up to Series A and Series B. What does a pre-seed round look like now in the age of AI? Like, what are the metrics? What do you look at? How do you assess team, product, traction?
Anish Acharya 6:36 ↗
I think the number one thing is like, you know, having a pitch without a prototype is no longer acceptable. You know, I mean, maybe if you're building a chip, maybe, but now it's just so trivial to be able to build things, and the best form of storytelling is through product. Well, that's what we all know. So I think you just — you have to come with a product, and ideally you're in market. You know, it may be early and there may be caveats, but it's so much easier for me to extrapolate from some sort of a, you know, small but still statistically significant sample than it is for me to kind of dream a dream alongside a founder. So I just think the kind of expectation of progress is pretty far ahead of what it was three years ago.
Caroline 7:12 ↗
Absolutely. Okay. And also, like, when you look at the market, because let's say you do something with Lovable or with Replit or other tools, and then you go into the market, you find a couple of customers, you do get traction. I guess for you guys as an investor, you want to see that this can get big enough, but at such an early stage, at pre-seed, you don't always know. So maybe the founders will have to pivot, maybe they will have to increase the market size. How do you look at the market?
Anish Acharya 7:39 ↗
Yeah. You know, there's almost two opposing ideas you have to hold in your head. But I often find this, and this is not the only way to illustrate the story, but I think being extremely ambitious in terms of where you want to go long-term, but being almost narrow in how you get there short-term. Like, I think the most common pattern for success is monopolization of a seemingly very small niche. And the question that you almost want to get is, 'Isn't that too small?' I think if you can get 80% market share in something that feels too small, you're going to start to discover the adjacencies around it. Versus when you try to compete in something that's highly competed and very horizontal, and, you know, the greatest lie we tell ourselves is, 'If I only get 1% of the market' — like, it's very hard to get 1% of the market because it's highly competed. So I'd say the alpha is where you can monopolize and dominate something even if it feels too small, and that is a great stepping stone in the sort of interest of doing something very, very large. I mean, like, famously Mark Zuckerberg, that you guys invested very early on, right? He was asked, like, how big did you want Facebook to be, and he was like, 'I wanted everyone at Harvard to use it.'

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APA

Acharya, A. (2026, October 22). Will OpenAI or Anthropic kill your startup? : Anish Acharya a16z [Interview transcript]. Venture Europe. CEOInterviews.AI. https://ceointerviews.ai/interview/3112856/

MLA

Anish Acharya. "Will OpenAI or Anthropic kill your startup? : Anish Acharya a16z." Venture Europe, 22 Oct. 2026. Transcript, CEOInterviews.AI, https://ceointerviews.ai/interview/3112856/.

BibTeX
@misc{acharya2026_3112856,
  author       = {Anish Acharya},
  title        = {Will OpenAI or Anthropic kill your startup? : Anish Acharya a16z},
  howpublished = {Interview transcript, Venture Europe. CEOInterviews.AI},
  year         = {2026},
  month        = {oct},
  url          = {https://ceointerviews.ai/interview/3112856/},
  note         = {Speaker-attributed transcript with timestamps}
}