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Joseph Chang
Executive Vice President & Chief Scientific Officer, NU SKIN ENTERPRISES -CL A

IWR - The Science of Anti-Aging: Why Your Supplements Aren't Working (Dr. Joe Chang) - 5 15 26

📅 May 15, 2026 Phaitoon Sarujikamjorn 33 MIN 60 VIEWS 126 SEGMENTS · 2 SPEAKERS
Is your body repairing itself as fast as it's breaking down? Dr. Joe Chang reveals the "Seesaw" theory of aging and how a major breakthrough in micronutrient science is changing how we stay young. Value Bullets: The fundamental difference between tissue damage and tissue repair. Why the "Recommended Daily Allowance" (RDA) is not enough for optimal health. The truth about "Methylation" and why some people can't absorb standard vitamins. How to break the cycle of chronic stress and "Beauty Sleep" sabotage. Using the PRISM scanner to get a "Report Card" for your internal health. Timestamps...

What Joseph Chang said

Written from the verified transcript and checked against it. Every figure links to the moment it was said.

Joseph Chang, Executive Vice President and Chief Scientific Officer at Nu Skin, discussed the science of aging and the launch of the new Life Pack. He described aging as a balance between tissue damage and repair, and positioned Life Pack as a micronutrient supplement that goes beyond recommended daily allowances to provide additional benefits. Chang highlighted the new tablet form, which is smaller and requires one tablet per day instead of two packets. He noted that the new formulation includes methylated vitamins like vitamin K2 to help those who cannot convert inactive forms, aiming to cover nearly 100% of consumers. He addressed the micronutrient needs of GLP-1 drug users and bariatric surgery patients, linking deficiencies to sarcopenia. Chang also discussed the role of sleep and stress in aging, and introduced the Prism as a nutritional health monitor that uses data from the S3 scanner to provide real-time feedback. He emphasized Nu Skin's identity as an anti-aging company, with Prism as the latest manifestation.

Key takeaways

  1. New Life Pack is now one small tablet per day instead of two packets, making it easier for customers to take.
  2. Life Pack is formulated with methylated vitamins like vitamin K2 to help those who cannot convert inactive forms, covering nearly 100% of consumers.
  3. Life Pack provides micronutrients above recommended daily allowances to offer additional health benefits.
  4. GLP-1 drug users and bariatric surgery patients are at risk of micronutrient deficiencies, which can lead to sarcopenia.
  5. Prism is a nutritional health monitor that translates S3 scanner data into a score to help users see their nutritional status and change behavior.

Numbers and commitments

FigureWhat it refers toTypeAt
90-95% of consumers who can benefit from previous Life Pack metric 9:41
100% of consumers covered by new Life Pack formulation metric 9:41

Chapters

  1. 0:00Life Pack launch and new form
  2. 2:01Aging as tissue damage and repair
  3. 3:35Micronutrients and Life Pack's role
  4. 8:14Methylated vitamins for better absorption
  5. 9:55GLP-1 users and micronutrient needs
  6. 15:15Sleep and tissue repair
  7. 17:41Stress and chronic stress effects
  8. 22:01Prism as nutritional health monitor
  9. 28:33Nu Skin's anti-aging future

Questions asked in this interview

12
  1. 1:19You know, it's much smaller than a capsule, isn't it, Buck?
  2. 1:28Like what causes aging in the body?
  3. 3:23So how does Life Pack then help with balance of tissue damage and tissue repair or even the Life Pack family?
  4. 12:07If you lack those micronutrients what are some of the ways that that manifests?
  5. 15:16How does sleep work into that whole formula of tissue?
  6. 15:52No, you have a hangover almost, right?
  7. 17:26And so how does stress impact that whole aging process?
  8. 21:26So, are there other areas that have a big impact on aging?
  9. 21:44Are there other, we talk about nutrition, right?
  10. 21:49Are there any things like that that we should be addressing?
  11. 27:43Where do you see us going?
  12. 31:51So stay tuned for more of those transformations you guys. But Joe, any closing remarks?
Joseph Chang 0:00 ↗
I'm just going to emphasize some of the really exciting things that you should take into account when we talk about stuff like that. So Buck and I talked and we just launched Life Pack.
Buck McMurray 0:15 ↗
Have we not? Yeah.
Joseph Chang 0:16 ↗
And you may not realize that Life Pack, we haven't really reformulated, that's not even the right word, reformulated Life Pack for a long time. And that's because we were waiting for the science to mature and because we knew the science was coming but we just didn't have the data yet. So now that we had, we are finally able to launch this Life Pack.
And just to remind you, what we have done, so many of you might have already gotten a box of it and you took the sachet. It's still the sachet. It's very good. And you see they're tablets now. Okay. They're very little tablets. It's almost like a mint if you will.
So, and one of the reasons that we wanted to go into that dosage form, I call it, is because I think you'll find it is much easier for your new customers and whoever to take that particular natural supplement.
Buck McMurray 1:19 ↗
You know, it's much smaller than a capsule, isn't it, Buck?
Joseph Chang 1:22 ↗
It is. It's much smaller and fewer to take and there's one a day instead of two packets a day.
Buck McMurray 1:28 ↗
So, it's a great upgrade in my opinion. Now, I want to back up a little bit. And you know, we've got your book here. And this is the updated version of it. And so, I wanted to hear from you your perspective on why do we age? Like what causes aging in the body?
Joseph Chang 1:50 ↗
Okay. And let's talk about that first and then talk about how Life Pack helps support an aging body.
Buck McMurray 1:59 ↗
Yeah. No, that's a great question, Buck.
Joseph Chang 2:01 ↗
And simply put, when I look at aging, right, and obviously there have been a lot of science done on it and so on to understand how we age. And there are lots of experiments, lots of different investigators conducting studies on it. But fundamentally when I distill all these things down, I'm a simple kind of guy, I like to know what is it driving at. Essentially aging is a simple balance. I almost look at it as a seesaw. You know, a seesaw rests on the fulcrum in the middle, right? And if they're perfectly balanced then it's great. So if I put aging in the middle, it's called a fulcrum, and when it gets out of balance on one side is tissue repair. Your body is constantly breaking down.
It's, I mean even when you exercise it's all good for us but you didn't realize in order for your muscles to get stronger and so on, it gets damaged. During exercise, you know, you don't see it but there is damage there. And then on the other side is the body has this capacity to repair. So when you look at aging, just think about it as tissue damage, tissue repair. And if you have both of those processes working optimally, you have balance.
Buck McMurray 3:23 ↗
Okay. So how does Life Pack then help with balance of tissue damage and tissue repair or even the Life Pack family?
Joseph Chang 3:35 ↗
Well, how does your body get healthy? What is it that really keeps your body healthy when you think about it? It's the food that we eat, isn't it? And what is food? Then I'll break that down for you. There are only two things in food. There is the macronutrients, the carbs, the proteins, the fats. That's your basic macronutrients. And then on the other side are those things that you don't feel. Those are called the micronutrients. The vitamins, the minerals, and so on. There are lots of other things too. Okay? So you need both.
If you don't have both, and once again it's about balance. Now when you take too much of the macronutrients, you know what happens? I don't have to go into that and we might talk about that a bit later. In other words, you add on weight.
Buck McMurray 4:25 ↗
Don't you? Yeah. Right.
Joseph Chang 4:27 ↗
So, but you have to eat a very nourishing meal. And that nourishment also comes from the micronutrients. That's what Life Pack is. You know, essentially we say look, the food is pretty obvious and all that, but these micronutrients sometimes it's missing from our diet.
Buck McMurray 4:49 ↗
Yeah, you know, it's because of a variety of reasons, including how we grow and process our foods now. They're not really very nourishing.
Joseph Chang 4:58 ↗
And also I would assume culturally the foods that we're eating in our fast-paced lives, they don't have the micronutrients.
Buck McMurray 5:06 ↗
No, Life Pack is not addressing the macronutrients. You're not getting the fats, carbohydrates, or the protein. It's addressing the lack of the micronutrients that we have in our diet and our lifestyles.
Joseph Chang 5:19 ↗
Absolutely. And what is the uniqueness that we do here at Nu Skin and that we also take into account is that we also know from science that those so-called recommended daily allowances, you might want and need to take even more benefits that you can get out of these micronutrients. And that's why we take into account with our Life Pack when we formulate it is to make sure the amount that we put in is more than you need, not just to satisfy the RDAs, the recommended daily allowances, but also to provide you with those additional benefits.
Buck McMurray 7:48 ↗
Okay, so just to recap, so we've got new form factor. It's in tablets, smaller and fewer to take, but we're also, one of the other benefits that we have of Life Pack is that we're not following RDA. We're actually putting in more. And I would assume this is all based off of when you're looking at the research of the ingredients, this is all based off of the science.
Joseph Chang 8:10 ↗
Absolutely.
Buck McMurray 8:10 ↗
Where you get a therapeutic benefit from the ingredients that you have in there.
Joseph Chang 8:14 ↗
Yeah. Okay. And there's a third one but you might want to remember that. So there are certain, albeit small but nonetheless there is a significant percentage of folks who are unable to process some of these vitamins into an active form. I call it, when you take it in a form usually you are taking it, for these people it's an inactive form.
Buck McMurray 8:40 ↗
Yeah.
Joseph Chang 8:40 ↗
Okay. For most of us, we have no problem to convert that to the active form because we have all the enzymes and all the necessary biochemistry in our body to do that. Some folks don't have that.
Buck McMurray 8:51 ↗
Yeah.
Joseph Chang 8:51 ↗
Well, we have overcome that now with the new Life Pack. Vitamin K, for example, we're doing it with vitamin K2 specifically.
Buck McMurray 9:00 ↗
And now everybody can get the benefits that you can get from a vitamin K nutrient. So it's not that these individuals they aren't able to absorb it, they absorb less.
Joseph Chang 9:13 ↗
They absorb less.
Buck McMurray 9:14 ↗
So when we have, they convert less.
Joseph Chang 9:16 ↗
They convert less. So if you've got a vitamin K2 or we talk about some of the B vitamins.
Buck McMurray 9:22 ↗
Exactly.
Joseph Chang 9:23 ↗
These are formulated in a way, and some of you might have heard the word or the buzzword methylation.
Buck McMurray 9:29 ↗
Uh-huh.
Joseph Chang 9:30 ↗
And so these are methylated to make sure that everybody is getting, they're able to convert them.
Buck McMurray 9:37 ↗
Yep.
Joseph Chang 9:39 ↗
And use them more efficiently.
Buck McMurray 9:41 ↗
Absolutely.
Joseph Chang 9:41 ↗
Okay. So we were able to handle well maybe 90, 95% if you will of every consumer who takes the Life Pack. But now we're pretty close 100% with the new Life Pack.
Buck McMurray 9:55 ↗
Okay. So, it sounds like we could go broad and we can say that everybody based off of the common diet and based off of how we're growing fruits and vegetables that they need this. But my marketing mind goes to like if we try to sell to everyone, we sell to no one. And so, you have to start looking at niches and understanding the needs and need states to be able to tell their story to them to market effectively. One of the demographics that we see right now in North America and is where I see that there is a potential need and I want to hear your take on this is we've got this weight loss phenomenon in North America where individuals are using a drug called GLP-1s to reduce appetite. They're eating less. So in eating less they're getting less of those macronutrients, the fats, the carbohydrates, the proteins, but at the same time they're getting less of the micronutrients.
Joseph Chang 10:58 ↗
Absolutely right about that.
Buck McMurray 11:00 ↗
And I've heard anecdotally that people that are on those they are scanning lower as well. So how, I mean I'm sure we have, I don't know. We haven't done any studies. I haven't seen any studies that show the impact of micronutrients or the Life Pack, the impact that it would have on somebody using one of those but it seems like there is definite need with this group of individuals that are using this.
Joseph Chang 11:29 ↗
Oh, absolutely, Buck. I mean, not just this group, there are certain other folks that we know that studies have been conducted, right? And that would be, you probably heard of a type of surgery for weight loss called bariatric, stomach stapling and all that kind of stuff. They also had a decrease in the amount of food that they take, right? Because the stomach is smaller now. So well unfortunately they don't compensate for that by taking or supplementing their food with a vitamin mineral or some micronutrient supplement.
Buck McMurray 12:07 ↗
So they suffer the same issue. If you are in one of those camps and I guess this could go for anybody. If you lack those micronutrients what are some of the ways that that manifests?
Joseph Chang 12:21 ↗
Uh you get, well one of the most evident one if I go back to the GLP-1 types of drugs and so on would be a condition called where the muscle doesn't stay as strong as it should.
Buck McMurray 12:39 ↗
Okay so that muscle degradation we call it.
Joseph Chang 12:43 ↗
Sarcopenia.
Buck McMurray 12:44 ↗
Sarcopenia, right. And that's sarco meaning muscle, penia is like reduction in muscle.
Joseph Chang 12:52 ↗
It's like osteopenia is reduction of bone mass. So sarcopenia reduction in muscle mass.
Buck McMurray 12:59 ↗
And if they have the right macronutrients that help support maintaining that muscle mass.
Joseph Chang 13:05 ↗
Absolutely. You see, your body is a chemical engine running all the time. Right. I would call it a biochemical engine. In order for your body to function, the chemistry has to happen in every cell, not just in the bone, not just in the muscle, every tissue literally will require these vitamins and minerals to act as what we call co-factors to run that engine. It's almost like an additive that you put onto your gas for your car to make it, you know, to get it up to a high octane or whatever to drive the engine. It's the same thing, right? It doesn't provide the energy but it's actually a very important accelerant for energy production in the body. Okay. So if you look at it from that perspective you can imagine all these folks they will require a micronutrient supplement. There's no doubt.
Buck McMurray 14:01 ↗
Yeah.
Joseph Chang 14:01 ↗
There's absolutely no doubt. It's almost in a way I would say maybe it's an unintended consequence of the success of these particular drugs. This is a godsend to the supplement folks or at least to the micronutrient supplements such as Life Pack. Every one of them would need it.
Buck McMurray 14:21 ↗
So everybody needs Life Pack in our day and age because of how we're growing our fruits and vegetables but also our diets. But there are some segments of the population that need them even more.
Joseph Chang 14:34 ↗
Absolutely.
Buck McMurray 14:36 ↗
Okay. So, let's dive into some of the other products that we have, scanner certified products. Or the Prism certified products. One of the questions that I wanted to ask you because we're talking micronutrients. And the need of micronutrients and you talked about that teeter-totter, the seesaw and the fulcrum. So one was tissue repair and tissue damage.
Joseph Chang 15:02 ↗
Yes.
Buck McMurray 15:03 ↗
So there's a lot of behaviors that help us, you know, repair our bodies. Right. And obviously eating the right types of macronutrients are going to help with that. Let's talk about sleep.
Joseph Chang 15:15 ↗
Yes.
Buck McMurray 15:16 ↗
How does sleep work into that whole formula of tissue? I would imagine it's tissue repair.
Joseph Chang 15:23 ↗
Absolutely. Somehow the body, you know, I've always wondered why do we sleep? Frankly, why do we need sleep? I think a lot of research nowadays would point towards the intended result of that if you have good and quality sleep is that it allows the body to repair. That's fundamentally what sleep does. You guys experience it, right? Don't you? If you don't have a good night's sleep, you don't feel good.
Buck McMurray 15:52 ↗
No, you have a hangover almost, right? When you wake up, you're yawning all day. And if you go and try to work out or exercise, you're not able to push as hard, you know.
Joseph Chang 16:01 ↗
Yeah. Because your body is active throughout the day. And in order to be active, every cell in your body is metabolizing in a way, right? And it's not 100% efficient. You are going to generate some byproducts that you need to get rid of. Okay? And the only time that you're really effective in getting rid of that is when you sleep.

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APA

Chang, J. (2026, May 15). IWR - The Science of Anti-Aging: Why Your Supplements Aren't Working (Dr. Joe Chang) - 5 15 26 [Interview transcript]. Phaitoon Sarujikamjorn. CEOInterviews.AI. https://ceointerviews.ai/interview/928201/

MLA

Joseph Chang. "IWR - The Science of Anti-Aging: Why Your Supplements Aren't Working (Dr. Joe Chang) - 5 15 26." Phaitoon Sarujikamjorn, 15 May. 2026. Transcript, CEOInterviews.AI, https://ceointerviews.ai/interview/928201/.

BibTeX
@misc{chang2026_928201,
  author       = {Joseph Chang},
  title        = {IWR - The Science of Anti-Aging: Why Your Supplements Aren't Working (Dr. Joe Chang) -   5 15 26},
  howpublished = {Interview transcript, Phaitoon Sarujikamjorn. CEOInterviews.AI},
  year         = {2026},
  month        = {may},
  url          = {https://ceointerviews.ai/interview/928201/},
  note         = {Speaker-attributed transcript with timestamps}
}