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Steve Nugent
Chief Science & Health Officer and Chairman of Scientific Advisory Board, MANNATECH INC

Product Focus: Glycan-4fx™ with Dr. Steve Nugent

🎥 Jun 09, 2026 📺 Mannatech ⏱ 10m 👁 60 views
🌱 Welcome to Mannatech! At Mannatech, we believe Glycans Are Life. For over 30 years, we've been pioneering Real Food Technology® solutions that support your wellness journey from the inside out. ✨ ABOUT MANNATECH: We're a global wellness company dedicated to transforming lives through innovative, science-backed nutritional supplements. Our products harness the power of glyconutrients and other natural compounds to support your body's optimal function. 🛒 SHOP OUR PRODUCTS: Explore our full range of wellness solutions at https://usa.mannatech.com/shop 🎯 FEATURED PRODUCTS: • Ambrotose LIFE...
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About Steve Nugent

Steve Nugent, Mannatech's Chief Science & Health Officer, has been promoting the company's new product Glycan-4fx in recent appearances. He stated that the product uses a proteoglycan extracted from fish collagen, which he said provides joint cushioning by helping retain fluid in the joints. Nugent claimed that in placebo-controlled human tests, a majority of participants reported significant mobility results within four days when proteoglycan was combined with phosphatidyl serine. He described the product as "patent pending" and emphasized its exclusivity as a business advantage for Mannatech associates, stating that "you don't want to sell something that anyone else can sell." In an April 2026 health and wellness call, Nugent asserted that Mannatech has spent "well over 50 million" dollars on research and called the company "the absolute king of glycans." He stated that supplementation is "a necessity" for optimal health and that "virtually no function in the human body does not involve glycans." Nugent also said that as people age, their systems become less efficient and require more supplementation, regardless of how well they feel.

Source: AI-verified profile updated from Steve Nugent's recent appearances. Browse all interviews →

Transcript (4 segments)
✨ AI-enhanced transcript with speaker attribution
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Steve Nugent0:00
Well, this new product Gan 4FX is really a step forward in terms of mobility. It's a different kind of approach than we've done before. I like the science, I like the ingredients, and I like the results. I like the really quick results with this. It's really pretty impressive. It's good science. It's been studied for quite a long time. So what we're doing now is we're using proteoglycan which is extracted from fish collagen. So you do have the collagen structural benefit there. But the proteoglycan, although proteoglycans do give you some amount of structural benefit, the really exciting thing about it is the fact that this is more for cushioning. And I know that sounds really good. If you've been having mobility problems, you're thinking, yeah, some cushion would be kind of good there. Well, we're talking about being able to retain the right kind of fluid in the right places in your joints so you have a lot more cushion. Now, the cushion obviously is going to make you feel better and it's going to allow you to be more mobile and hopefully more active as well as a result of feeling that sort of cushion in your step, if you will.
So think of glycan as the big umbrella. Okay, a glycan is the big thing under which everything else falls. One of those things would be proteoglycans. So a proteoglycan is a glycan also, but it's different in its structure. The proteoglycan by itself has some really strong properties to help with mobility. And by itself, it's a very good mobility ingredient. What could make it better? Well, there have been two studies and these are good studies. These are placebo-controlled studies. And in the studies, they tried to have people just on the proteoglycan alone, the exact same one that we're using. And then they also had a group that had the proteoglycan combined with something called phosphatidylserine. Now you may see this listed in a lot of literature simply as PS, just the letters PS. So phosphatidylserine, what is it normally used for? Well, if you were going to look it up on the internet, and inevitably everyone will, you're going to find lots of references to brain function, memory function, cognitive function, and all of that's true. And that's what phosphatidylserine has been studied for the most. But everything in nutrition, so many people don't realize this, but everything in nutrition has at least one co-actor that makes it work better. So, what you want to do is find out what's that co-actor that you want to combine to ingredient A to get the maximum possible results from ingredient A. Well, as the studies went on, they found that what we want is phosphatidylserine or PS. So when you combine phosphatidylserine with this very special proteoglycan which is extracted from fish collagen, when you combine those two, the results go from good to great. You start as an example, proteoglycan alone, decent mobility results in about 30 days. Proteoglycan combined with phosphatidylserine, really significant results in four days. The majority of the people studied, not 100%, nothing's ever 100%. But the majority of the people studied, significant results in only four days. That's astounding. I mean, that's amazing.
So, this has got me pretty excited just because these results are so fast. And you know, in our industry, what really helps is if people can say, 'I feel the difference.' And the faster you feel the difference, the more likely you are to call up your friend, your coworker, your neighbor, and say, you know what, I really feel a difference with this stuff. In fact, I felt the difference with this in just a few days. So that makes it an even better product. Now, of course, as a healthcare practitioner, I'm very, very concerned about how does it function? How does it perform to help people with their health? And this clearly does. But on the other side of that, on the business side of that, feel-good products really help you build your business. There's no question about that. And there's no amount of literature, there's no amount of video that you can watch from some scientist like myself that will be as good as somebody calling up their friend and saying, 'You know what? Four days I felt terrific. You got to try this stuff. I don't know how it works. Who cares? It works.' So, that's what people will be saying when they use this product. Now, to be fair, they tested this product. They did the first test for results at four days and then at seven days and then at 14 days and then again at 30 days. And they saw different results as they moved up the scale. But the result of having the majority of people feeling the difference in their joints in only four days, that's astounding. I mean, that's something I've never heard of before.
Now, the Manapol in it, because we know, you know, I've been working with Manapol since 1995. I have so much confidence in that product because I've seen what it can do for all these years. If you want anything to work better, well, combine some Ambrotose or Manapol with it. If you want anything to have the full potential to function the way it was designed to function, you add Ambrotose or Manapol to it. That's what I've seen repeatedly for all of these decades. It's amazing stuff. So, what a combination. By the way, this is patent pending. And of course, exclusivity is something that for the business builders, they have to love that. You want exclusivity. You don't want to sell something that anyone else can sell. That's boring and that's not a good way to build a business. But exclusivity, ah, science that nobody else has. Yes, that's what you want. That's the story. That's the way to tell people what you have. And it can be exciting for them, not just for me as a science guy. So, this is a great product, Glycan 4FX. It's just a super product for mobility. Realistically, people of probably over 40 are going to be saying, 'This is my product because I needed help with my mobility.' And of course, the older you go, the more people are going to say that. But I'm telling everyone, if you're smart, you should be doing this at a much younger age. Get a head start. It's going to be worth your while as you get older. It's hard to convince anybody of that if they're not older yet. But trust me on this. I'm an expert in this area. And of course, I am unfortunately older. And I have felt the difference. I can tell you the difference in my personal mobility that has changed from when I was 30, 40, and of course where I am now in my early 70s. Heck, I was a US Marine. There wasn't pretty much anything I couldn't do physically. Not really the case anymore. Now I do need some mobility assistance and this is a great product for that. I'm loving this product. I've been taking it myself. This has been tested, as I say, in placebo-controlled human tests, two of them. We are very confident about how this product functions and very confident about this combination of ingredients with this special exclusive proteoglycan and phosphatidylserine and Manapol all combined. So this is, I don't know, I can't say enough positive about this. I love the science. I love the combination of ingredients. I love the function. I love the way it functions. And I love, especially for our business, that it's a feel-good product. You cannot go wrong with a feel-good product. Anybody who says, 'Oh, well, you know, I have trouble. I've been talking to my friend or my neighbor and they don't want to listen to me.' And how about if you just say, 'You know what? I know that you've been having some mobility issues. Here, here's a bottle of this great product from Mannatech. Give it a try. In fact, give me a call in four or five days. Let me know how you feel.' You talk about an easy sale. Oh my gosh, it is so easy. And I'm looking forward to this for all of our Mannatech associates, not just for all the people that I want to see improve their health because they've improved their mobility.