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Alex Rampell

General Partner, Andreessen Horowitz

Verified interview transcripts, podcast appearances, and direct quotes from Alex Rampell, General Partner at Andreessen Horowitz. AI-verified speaker identity with full-text searchable transcripts.

Recent appearances

  • Why a $1M Startup Wasn’t Worth Building in the Age of AI

    October 19, 2026 · 📺 a16z

    Jean-Denis Greze was CTO of Plaid. His next startup, an AI tax product for small businesses, made nearly $1M in its first year and was on track for $2.5M to $3M. He shut it down anyway. The reason: in the age of AI, it was never going to be venture scale. Incumbents could use the same technology to automate tax prep for their existing customers faster than a startup could win market share. Tax is also sold once a year, so he had about a one-month window to pivot before the door closed. The pivot became Town, an AI assistant that works from your email and calendar. It found product-market fit…

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  • What Happens When AI Agents Can Spend Your Money?

    October 15, 2026 · 📺 a16z

    What happens when AI agents start spending your money? VGS' Terry Angelos argues that agentic commerce will need new payment infrastructure that gives AI the ability to transact without sacrificing the protections consumers expect. Terry joins a16z General Partner Alex Rampell to discuss the emerging wallet wars, how agentic tokens could enable secure purchases, and what happens when an AI buys the wrong thing. They also explore why merchants may resist agentic commerce, how AI could change credit card rewards and subscriptions, and who controls the customer relationship when agents make pur…

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  • Why the Next Generation of Enterprise Software Looks Nothing Like Salesforce

    September 16, 2026 · 📺 a16z

    a16z’s Alex Rampell and Joe Schmidt sit down with Lightfield co-founder and CEO Keith Peiris to discuss what it takes to rethink the CRM for an AI-native world, and the unusual pivot that got him there. Keith previously built Tome to 25 million users, but eventually walked away from the product after concluding that the underlying technology couldn’t capture enough context about a presenter, their audience, and the relationship between them. Starting again, his team followed customers from AI presentations into sales workflows and eventually found a harder problem: making sense of the fragmen…

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  • Why AI Agents Could Finally Reinvent the Credit Card

    September 03, 2026 · 📺 a16z

    Erik Torenberg is joined by a16z General Partner Alex Rampell and Affirm Co-Founder and CEO Max Levchin for a conversation on 25 years of fintech, from the early days of digital payments to the origins of Affirm and the next generation of agentic commerce. Max and Alex revisit what surprised them most about how payments evolved, why the card interface has been so difficult to displace, and why even the smallest corners of payments can become enormous markets. They also trace the early idea maze behind Affirm, from "pay with your identity" and the pajama problem to the realization that install…

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  • “Every small business should run itself” | Lassie with a16z

    July 30, 2026 · 📺 a16z

    Alex Rampell and Olivia Moore speak with Lassie cofounders Steijn Pelle and Frédéric Renken about bringing AI to one of the most overlooked parts of the economy: small businesses. Inspired by time spent working inside dental practices, Pelle and Renken set out to automate the administrative work that keeps healthcare providers away from patients. They discuss how AI agents are changing billing, insurance claims, patient payments, and other operational workflows, allowing practices to spend less time on paperwork and more time delivering care. The conversation explores AI agents, software tha…

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  • Atlassian CEO on the SaaS Apocalypse, AI Agents & What Comes Next

    March 06, 2026 · 📺 a16z

    Alex Rampell and Erik Torenberg speak with Mike Cannon-Brookes, cofounder and CEO of Atlassian, about how to make sense of the SaaS selloff, why not all software companies face the same AI-driven risks, and how Atlassian is thinking about the shift from records to processes. They also examine the real design challenge of getting everyday users to trust and benefit from AI agents in enterprise workflows. Timestamps: 00:00 — Introduction 03:16 — Risk Level Has Gone Up 06:44 — Three Types of SaaS Companies 11:07 — Vibe Coding Is Preposterous 14:23 — Businesses Are a Set of Processes 31:25 — AI C…

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  • Alex Rampell: The Best Founders Materialise Capital, Customers & Labour | The Future of Venture

    January 12, 2026 · 📺 20VC with Harry Stebbings

    Alex Rampell is a General Partner at Andressen Horowitz, where he leads their $1.7BN apps fund. Just last week, a16z announced they had raised $15BN for their latest funds, over 20% of all capital raised by venture firms. At a16z, Alex has led deals into Plaid, Mercury and OpenDoor to name a few. ----------------------------------------------- Timestamps: 00:00 Intro 01:26 How to Do 5x on a $15BN Fund Pool? 04:15 What Two Groups of Funds Will Win the Next Decade in VC? 15:13 What Three Things Are the Best Founders Able to Do? 20:35 The Best Companies Have Hostages, Not Customers 32:15 The Tw…

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