Michel Del Buono

Operating Partner & Chief Investment Officer, a16z Perennial, Andreessen Horowitz

Search every verified Michel Del Buono interview, podcast appearance, and on-the-record quote — each transcript cross-checked by AI and human review to confirm speaker identity. Michel Del Buono, Chief Investment Officer of a16z Perennial, the multi-family office associated with Andreessen Horowitz, discussed wealth management strategies for high-net-worth individuals in two podcast appearances in early 2026. He described Perennial as a multi-family office serving the firm's principals and various founders, built in response to what he characterized as shortcomings in traditional wealth management and institutional asset management for taxable individuals. He emphasized the importance of professional guidance in portfolio construction, comparing the need for decisive advice to medical treatment. Del Buono addressed tax and estate planning for founders facing potential liquidity events, such as a rumored SpaceX IPO. He noted that founders with a zero cost basis face long-term capital gains taxes that can reach upwards of 35% depending on the state, and he highlighted the Qualified Small Business Stock (QSBS) benefit, which can exempt up to $15 million of proceeds from stock sales for early founders. He also discussed the active secondary market for shares in private companies like Anthropic, OpenAI, Stripe, and Anduril, noting the structural challenges employees face in transferring stock and the importance of understanding different investment vehicles. He stated his goal is to educate people on these complex topics.